Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marius Walter"'
Autor:
Chris Carrico, Andrew Cruz, Marius Walter, Jesse Meyer, Cameron Wehrfritz, Samah Shah, Lei Wei, Birgit Schilling, Eric Verdin
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Lysine Nɛ-acylations, such as acetylation or succinylation, are post-translational modifications that regulate protein function. In mitochondria, lysine acylation is predominantly non-enzymatic, and only a specific subset of the proteome is
Externí odkaz:
https://doaj.org/article/b718fbde6dbd4edebb61ac04bfebc4d0
Autor:
Bjoern Meyer, Jeanne Chiaravalli, Stacy Gellenoncourt, Philip Brownridge, Dominic P. Bryne, Leonard A. Daly, Arturas Grauslys, Marius Walter, Fabrice Agou, Lisa A. Chakrabarti, Charles S. Craik, Claire E. Eyers, Patrick A. Eyers, Yann Gambin, Andrew R. Jones, Emma Sierecki, Eric Verdin, Marco Vignuzzi, Edward Emmott
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
During SARS-CoV-2 replication, viral and cellular proteases play crucial roles and have been shown to be promising anti-viral targets. Here, Meyer et al. apply mass spectrometry to characterize the proteolytic cleavage profile of viral and cellular p
Externí odkaz:
https://doaj.org/article/09cd9fa5dad54609b514710cffa2869d
Autor:
Marius Walter, Irene P Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L Lam, Jennifer M Hayashi, Andrew Cruz, Samah Shah, Frank W Soveg, John D Gross, Nevan J Krogan, Keith R Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010811 (2022)
SARS-CoV-2 non-structural protein Nsp14 is a highly conserved enzyme necessary for viral replication. Nsp14 forms a stable complex with non-structural protein Nsp10 and exhibits exoribonuclease and N7-methyltransferase activities. Protein-interactome
Externí odkaz:
https://doaj.org/article/19538024418c4582aee777208e569149
Autor:
Marius Walter, Eric Verdin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Current gene drive strategies are restricted to sexually reproducing species. Here the authors develop a gene drive in herpesviruses that allows the spread of an engineered trait through a viral population.
Externí odkaz:
https://doaj.org/article/50ab1c9b18a540458b8c1157bc4c41f5
Publikováno v:
eLife, Vol 8 (2019)
During early mammalian development, the chromatin landscape undergoes profound transitions. The Zdbf2 gene—involved in growth control—provides a valuable model to study this window: upon exit from naïve pluripotency and prior to tissue different
Externí odkaz:
https://doaj.org/article/afd19ac36c754f5ab0c7aa47ff94940a
Publikováno v:
eLife, Vol 5 (2016)
DNA methylation is extensively remodeled during mammalian gametogenesis and embryogenesis. Most transposons become hypomethylated, raising the question of their regulation in the absence of DNA methylation. To reproduce a rapid and extensive demethyl
Externí odkaz:
https://doaj.org/article/03ff8dec6c8743a786f298097cac8a09
Autor:
Clara Roidor, Laurène Syx, Emmanuelle Beyne, Dina Zielinski, Aurélie Teissandier, Caroline Lee, Marius Walter, Nicolas Servant, Karim Chebli, Déborah Bourc’his, M. Azim Surani, Maud Borensztein
Random X-chromosome inactivation (XCI) is a hallmark of female mammalian somatic cells. This epigenetic mechanism, mediated by the long non-coding RNAXist, occurs in the epiblast and is stably maintained to ensure proper dosage compensation of X-link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::567f489b5528b5640ca7fdbe7b48f52e
https://doi.org/10.1101/2023.04.25.532252
https://doi.org/10.1101/2023.04.25.532252
Autor:
Mathieu Schulz, Aurélie Teissandier, Elena de la Mata, Mélanie Armand, Julian Iranzo, Fatima El Marjou, Pierre Gestraud, Marius Walter, Sarah Kinston, Berthold Göttgens, Maxim V.C. Greenberg, Deborah Bourc’his
Somatic DNA methylation is established early during mammalian development, as embryonic cells transition from naive to primed pluripotency. This precedes the emergence of the three somatic germ layers, but also the segregation of the germline that un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e270597b91dc3acbd924daa8a569154
https://doi.org/10.1101/2022.10.22.513040
https://doi.org/10.1101/2022.10.22.513040
Autor:
Marius Walter, Ireneusz Habrylo, Kyle A. Raymond, Satish K. Pillai, Melanie Ott, Tugsan Tezil, Steven G. Deeks, Daniela Boehm, Philip A. Hull, Irene P. Chen, Albert Vallejo-Gracia, Andrew Cruz, Emilie Besnard, Karsten Krey, Eric Verdin, Rosalba Perrone, Emilie Battivelli
Publikováno v:
Nature microbiology
Nature microbiology, vol 5, iss 9
Nature microbiology, vol 5, iss 9
Quiescence is a hallmark of CD4+ T cells latently infected with human immunodeficiency virus 1 (HIV-1). While reversing this quiescence is an effective approach to reactivate latent HIV from T cells in culture, it can cause deleterious cytokine dysre
Autor:
Maxim V. C. Greenberg, Déborah Bourc'his, Daan Noordermeer, Aurélie Teissander, Marius Walter
SUMMARYDuring early mammalian development, the genome undergoes profound transitions in chromatin states, topological organization and recruitment ofcisregulatory factors involved in transcriptional control. How these three layers of gene regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f072a9c81b02317ba32c3f50f23c305
https://halshs.archives-ouvertes.fr/halshs-03437256
https://halshs.archives-ouvertes.fr/halshs-03437256