Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marius T. Wenz"'
Autor:
Guiyang Yao, Simone Kosol, Marius T. Wenz, Elisabeth Irran, Bettina G. Keller, Oliver Trapp, Roderich D. Süssmuth
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
The occurrence of isomers of the bicyclic octapeptide α-amanitin, which presents a macrolactam with a tryptathionine cross-link forming a handle, has been reported under the term of atropoisomers. Here, the authors synthesize its analogs and analyse
Externí odkaz:
https://doaj.org/article/ffa6050476a7482bbc3dca488bc7c362
Amatoxins are strong inhibitors of RNA polymerase II, and cause cell death. Because of their cytotoxicity they are candidates for anti-cancer drugs, and understanding their structure-activity relationship is crucial. Amatoxins have a rigid bicyclic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d01a9fca1fc5819615bb0c181d6d7b4
https://doi.org/10.1101/2022.12.21.521444
https://doi.org/10.1101/2022.12.21.521444
Autor:
Bettina G. Keller, Hendrik Gruß, Guiyang Yao, Andreas Pahl, Marius T. Wenz, Simone Kosol, Caroline H. Knittel, Torsten Hechler, Alexandra Braun, Roderich D. Süssmuth, Christian Lutz
Publikováno v:
Journal of the American Chemical Society. 143:14322-14331
Synthetic methods on the macrocyclization of peptides are of high interest since they facilitate the synthesis of various types of potentially bioactive compounds, e.g. addressing targets like protein-protein-interactions. Herein, we report on an eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea3c528059bc7ff978e0918406aab84
https://doi.org/10.1021/jacs.1c06565
https://doi.org/10.1021/jacs.1c06565
Autor:
Stevan Aleksić, Jana Sticht, Bettina G. Keller, Marius T. Wenz, Miriam Bertazzon, Christian Freund, Daniela Gjorgjevikj
Publikováno v:
Journal of chemical information and modeling. 62(24)
Protein-protein interactions often rely on specialized recognition domains, such as WW domains, which bind to specific proline-rich sequences. The specificity of these protein-protein interactions can be increased by tandem repeats, i.e. two WW domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637e1a040acfc99045b524c3028b0baf
https://pubmed.ncbi.nlm.nih.gov/35347992
https://pubmed.ncbi.nlm.nih.gov/35347992