Zobrazeno 1 - 10
of 711
pro vyhledávání: '"Marius M, Hoeper"'
Autor:
Hunter Gillies, Murali M. Chakinala, Benjamin T. Dake, Jeremy P. Feldman, Marius M. Hoeper, Marc Humbert, Zhi‐Cheng Jing, Jonathan Langley, Vallerie V. McLaughlin, Ralph W. Niven, Stephan Rosenkranz, Xiaosha Zhang, Nicholas S. Hill
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract AV‐101 (imatinib) powder for inhalation, an investigational dry powder inhaled formulation of imatinib designed to target the underlying pathobiology of pulmonary arterial hypertension, was generally well tolerated in healthy adults in a p
Externí odkaz:
https://doaj.org/article/6cca6181d66a4a5aadc281acfa6b68ed
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-6 (2022)
Externí odkaz:
https://doaj.org/article/956b73a90d2b40ac9d0b985c891d5d98
Autor:
Vivienne Theobald, Ekkehard Grünig, Nicola Benjamin, Hans‐Jürgen Seyfarth, Michael Halank, Marc A. Schneider, Sarah Richtmann, Daniel Kazdal, Katrin Hinderhofer, Panagiota Xanthouli, Benjamin Egenlauf, Satenik Harutyunova, Marius M. Hoeper, Danny Jonigk, Richard Sparla, Martina U. Muckenthaler, Christina A. Eichstaedt
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Iron deficiency is common in idiopathic and heritable pulmonary arterial hypertension patients (I/HPAH). A previous report suggested a dysregulation of the iron hormone hepcidin, which is controlled by BMP/SMAD signaling involving the bone m
Externí odkaz:
https://doaj.org/article/06906adb9d074ed8bf1540d8e0c8f963
Autor:
Klaus Stahl, Philipp Wand, Benjamin Seeliger, Pedro David Wendel-Garcia, Julius J. Schmidt, Bernhard M. W. Schmidt, Andrea Sauer, Felix Lehmann, Ulrich Budde, Markus Busch, Olaf Wiesner, Tobias Welte, Hermann Haller, Heiner Wedemeyer, Christian Putensen, Marius M. Hoeper, Christian Bode, Sascha David
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background Recently, a randomized controlled trial (RCT) demonstrated rapid but individually variable hemodynamic improvement with therapeutic plasma exchange (TPE) in patients with septic shock. Prediction of clinical efficacy in specific s
Externí odkaz:
https://doaj.org/article/b74703fcb78a45b2863d0b269f550a81
Autor:
Nina Rittgerodt, Thorben Pape, Markus Busch, Lena S. Becker, Andrea Schneider, Heiner Wedemeyer, Benjamin Seeliger, Julius Schmidt, Anna Maria Hunkemöller, Jan Fuge, Wolfgang Knitsch, Christine Fegbeutel, Hans-Jörg Gillmann, Bernhard C. Meyer, Marius M. Hoeper, Jan B. Hinrichs, Sascha David, Klaus Stahl
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background Non-occlusive mesenteric ischemia (NOMI) is a life-threatening condition occurring in patients with shock and is characterized by vasoconstriction of the mesenteric arteries leading to intestinal ischemia and multi-organ failure.
Externí odkaz:
https://doaj.org/article/56038b50d1734f4daa97639702d28323
Autor:
Hunter Gillies, Ralph Niven, Benjamin T. Dake, Murali M. Chakinala, Jeremy P. Feldman, Nicholas S. Hill, Marius M. Hoeper, Marc Humbert, Vallerie V. McLaughlin, Martin Kankam
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background Oral imatinib has been shown to be effective, but poorly tolerated, in patients with advanced pulmonary arterial hypertension (PAH). To maintain efficacy while improving tolerability, AV-101, a dry powder inhaled formulation of imatinib, w
Externí odkaz:
https://doaj.org/article/6e8ff00f40604cb1bb338a1660e59c87
Autor:
J. Gerry Coghlan, Sean Gaine, Richard Channick, Kelly M. Chin, Camille du Roure, J. Simon R. Gibbs, Marius M. Hoeper, Irene M. Lang, Stephen C. Mathai, Vallerie V. McLaughlin, Lada Mitchell, Gérald Simonneau, Olivier Sitbon, Victor F. Tapson, Nazzareno Galiè
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Further understanding of when to initiate therapies in pulmonary arterial hypertension (PAH) is important to improve long-term outcomes. Post hoc analyses of GRIPHON (NCT01106014) and exploratory analyses of TRITON (NCT02558231) suggested benefit of
Externí odkaz:
https://doaj.org/article/cf357fc51af24a7796e8e8637b6468a1
Autor:
Christina A. Eichstaedt, Zoe Saßmannshausen, Memoona Shaukat, Ding Cao, Panagiota Xanthouli, Henning Gall, Natascha Sommer, Hossein-Ardeschir Ghofrani, Hans-Jürgen Seyfarth, Marianne Lerche, Michael Halank, Janina Kleymann, Nicola Benjamin, Satenik Harutyunova, Benjamin Egenlauf, Katrin Milger, Stephan Rosenkranz, Ralf Ewert, Hans Klose, Marius M. Hoeper, Karen M. Olsson, Mareike Lankeit, Tobias J. Lange, Katrin Hinderhofer, Ekkehard Grünig
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background A genetic predisposition can lead to the rare disease pulmonary arterial hypertension (PAH). Most mutations have been identified in the gene BMPR2 in heritable PAH. However, as of today 15 further PAH genes have been described. Th
Externí odkaz:
https://doaj.org/article/1de528004b62464999a9e805a210de5e
Autor:
Klaus Stahl, Uta Carola Hillebrand, Yulia Kiyan, Benjamin Seeliger, Julius J. Schmidt, Heiko Schenk, Thorben Pape, Bernhard M. W. Schmidt, Tobias Welte, Marius M. Hoeper, Agnes Sauer, Malgorzata Wygrecka, Christian Bode, Heiner Wedemeyer, Hermann Haller, Sascha David
Publikováno v:
Intensive Care Medicine Experimental, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract Background Disruption of the endothelial glycocalyx (eGC) is observed in septic patients and its injury is associated with multiple-organ failure and inferior outcomes. Besides this biomarker function, increased blood concentrations of shedd
Externí odkaz:
https://doaj.org/article/b78f2c9b0af84ac4b2fcd961d9816631
Autor:
Sabine K. Maschke, Thomas Werncke, Cornelia L. A. Dewald, Lena S. Becker, Timo C. Meine, Karen M. Olsson, Marius M. Hoeper, Frank K. Wacker, Bernhard C. Meyer, Jan B. Hinrichs
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract To evaluate mosaic perfusion patterns and vascular lesions in patients with chronic thromboembolic pulmonary hypertension (CTEPH) using C-Arm computed tomography (CACT) compared to computed tomography pulmonary angiography (CTPA). We include
Externí odkaz:
https://doaj.org/article/903cc25d212749cdbe99e769b426adc0