Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Marius J Giphart"'
Autor:
A Salvador Peña, J Bart A Crusuis, Marco Oudkerk Pool, Mercedes Gracia Casanova, Gerard Pals, Stephan GM Meuwissen, Marius J Giphart
Publikováno v:
Canadian Journal of Gastroenterology, Vol 7, Iss 2, Pp 71-75 (1993)
Externí odkaz:
https://doaj.org/article/097ea40b89ed410fb0f4e625ffb0edc8
Autor:
Mara v.d. Bijl, Marja C. J. A. Eggermond, J. D'Amaro, Fei Hongming, Marius J. Giphart, Geziena M.Th. Schreuder, René R. P. Vries, Marcel G. J. Tilanus
Publikováno v:
Tissue Antigens. 28:218-227
HLA-D/DR alleles as defined by cellular and serological typing can also be identified by biochemical methods. The Southern blot technique provides an additional typing facility which can be applied to DNA obtained from any source of nucleated cells.
Autor:
R. E. Bontrop, Marius J. Giphart, R. T. Miltenburg, Geziena M.Th. Schreuder, E. M. A. Mikulski
Publikováno v:
Tissue Antigens. 27:22-31
We have analyzed the HLA class II gene products from HLA-DRw6 homozygous cells. Epstein-Barr virus-transformed B-cell lines were internally labeled with [35S]-methionine. An NP-40 lysate of the cells was subjected to immunoprecipitation, first with a
Publikováno v:
Tissue Antigens. 28:129-135
The polymorphism of the HLA system has been defined by alloantisera, monoclonal antibodies, MLC reactivity, protein chemistry and RFLP patterns in DNA analysis. Typing for the alleles of HLA-DR at the DNA level as an additional typing technique is us
Autor:
Bart O. Roep, P. Eerligh, A. R. Van Der Slik, B. P. C. Koeleman, I. Van Den Eng, Marius J. Giphart, Ilias I.N. Doxiadis
Publikováno v:
Tissue Antigens. 69:348-353
The extended major histocompatibility complex (xMHC) has been studied intensively with regard to type 1 diabetes (T1D) predisposition. So far, little attention has been given to the subregion centromeric of MHC class II. We selected five single nucle
Autor:
Bart O. Roep, Erik Thorsby, Dag E. Undlien, Frank Dudbridge, Bobby P. C. Koeleman, Francesco Cucca, Benedicte A. Lie, John A. Todd, Rindert R. P. De Vries, Marius J. Giphart
Publikováno v:
GENES AND IMMUNITY, 5(5), 381-388. Nature Publishing Group
Alleles of HLA class II genes DQB1, DQA1, and DRB1 in the MHC region are major determinants of genetic predisposition to type 1 diabetes (T1D). Several alleles of each of these three loci are associated with susceptibility or protection from disease.
Autor:
Frank Dudbridge, G. Jan Bruining, Marius J. Giphart, P. Eerligh, B. P. C. Koeleman, Bart O. Roep
Publikováno v:
Genes & Immunity. 5:36-40
Genetic association with type 1 diabetes (T1D) has been established for two chromosomal regions: HLA DQ/DR (IDDM1) and INS VNTR (IDDM2). To identify additional genetic markers, we tested polymorphisms in regulatory regions of several cytokine and imp
Autor:
Bart O. Roep, Arno R. van der Slik, G. Jan Bruining, Willem Verduijn, Bobby P. C. Koeleman, Marius J. Giphart
Publikováno v:
Diabetes. 52:2639-2642
Killer cell immunoglobulin-like receptors (KIRs) modulate natural killer cell and T-cell function by interacting with HLA class 1 ligands on target cells. Both KIR and HLA are highly polymorphic. We studied the influence of KIR and HLA class 1 genes
Publikováno v:
Immunogenetics, 55(4), 203-209. SPRINGER
Loss of expression of human leukocyte antigen (HLA) class II molecules on tumor cells affects the onset and modulation of the immune response through lack of activation of CD4(+) T lymphocytes. Previously, we showed that the frequent loss of expressi
Autor:
Bob J. van Hilten, Bart O. Roep, Arno R. van der Slik, Marius J. Giphart, Willem‐Johan T. van de Beek
Publikováno v:
Pain. 103:93-97
An association between HLA-DR13 and patients with complex regional pain syndrome (CRPS) who progressed towards multifocal or generalized tonic dystonia was recently reported. We now report on a new locus, centromeric in HLA-class I, which was signifi