Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marius Gedgaudas"'
Autor:
Jaka Dernovšek, Živa Zajec, Goran Poje, Dunja Urbančič, Caterina Sturtzel, Tjaša Goričan, Sarah Grissenberger, Krzesimir Ciura, Mateusz Woziński, Marius Gedgaudas, Asta Zubrienė, Simona Golič Grdadolnik, Irena Mlinarič-Raščan, Zrinka Rajić, Andrej Emanuel Cotman, Nace Zidar, Martin Distel, Tihomir Tomašič
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 116941- (2024)
The development of new anticancer agents is one of the most urgent topics in drug discovery. Inhibition of molecular chaperone Hsp90 stands out as an approach that affects various oncogenic proteins in different types of cancer. These proteins rely o
Externí odkaz:
https://doaj.org/article/483114562b034ad18b22bbfe461393c1
Autor:
Martynas Bagdonas, Kamilė Čerepenkaitė, Aurelija Mickevičiūtė, Rūta Kananavičiūtė, Birutė Grybaitė, Kazimieras Anusevičius, Audronė Rukšėnaitė, Tautvydas Kojis, Marius Gedgaudas, Vytautas Mickevičius, Daumantas Matulis, Asta Zubrienė, Jurgita Matulienė
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13491 (2023)
The severe acute respiratory syndrome-causing coronavirus 2 (SARS-CoV-2) papain-like protease (PLpro) and main protease (Mpro) play an important role in viral replication events and are important targets for anti-coronavirus drug discovery. In search
Externí odkaz:
https://doaj.org/article/34030b2d3c184dfc9e91c78da7b6d12a
Publikováno v:
Drug Discovery Today. 27:2076-2079
The thermal shift assay is one of the most universal techniques to determine protein-ligand affinities ranging from millimolar to picomolar levels in a single ligand dosing experiment. However, the complexity of thermodynamic data analysis leads to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d2579f640ba0a87ba7dd1d4af89198
https://doi.org/10.1016/j.drudis.2022.05.008
https://doi.org/10.1016/j.drudis.2022.05.008
Autor:
David D. Timm, Jelena Jachno, Saulius Gražulis, Vaida Linkuvienė, Lina Baranauskienė, Asta Zubrienė, Alexey Smirnov, Jurgita Revuckienė, Abdul Waheed, Vilma Michailovienė, Aurelija Mickevičiūtė, Enrico Di Cera, Edita Čapkauskaitė, William S. Sly, Zhiwei Chen, Elena Manakova, Daumantas Matulis, Marius Gedgaudas, Jurgita Matulienė
Publikováno v:
European Biophysics Journal. 47:271-290
Membrane-associated carbonic anhydrase (CA) isoform IV participates in carbon metabolism and pH homeostasis and is implicated in the development of eye diseases such as retinitis pigmentosa and glaucoma. A series of substituted benzenesulfonamides we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d90593a6085f4596ef71e4104dbf64
https://doi.org/10.1007/s00249-017-1256-0
https://doi.org/10.1007/s00249-017-1256-0