Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marius Costel Alupei"'
Autor:
Marius Costel Alupei, Pallab Maity, Philipp Ralf Esser, Ioanna Krikki, Francesca Tuorto, Rosanna Parlato, Marianna Penzo, Adrian Schelling, Vincent Laugel, Lorenzo Montanaro, Karin Scharffetter-Kochanek, Sebastian Iben
Publikováno v:
Cell Reports, Vol 23, Iss 6, Pp 1612-1619 (2018)
Summary: Retarded growth and neurodegeneration are hallmarks of the premature aging disease Cockayne syndrome (CS). Cockayne syndrome proteins take part in the key step of ribosomal biogenesis, transcription of RNA polymerase I. Here, we identify a m
Externí odkaz:
https://doaj.org/article/98f1ad7eb84b485e8b920342542da1cf
Autor:
Robin Assfalg, Marius Costel Alupei, Maximilian Wagner, Sylvia Koch, Omar Garcia Gonzalez, Adrian Schelling, Karin Scharffetter-Kochanek, Sebastian Iben
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179843 (2017)
The nucleolus has long been considered to be a pure ribosome factory. However, over the last two decades it became clear that the nucleolus is involved in numerous other functions besides ribosome biogenesis. Our experiments indicate that the activit
Externí odkaz:
https://doaj.org/article/591eb3bbe4ea4ff1a21513df0458c341
Publikováno v:
Cancer Letters. 356:946-952
ABS T RA C T Statins possess antitumor actions at doses 100- to 500-fold higher than those needed to lower cholesterol levels. Thus, the antitumor efficacy of statins could be improved greatly by using tumor-targeted delivery systems. Therefore the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae24c1d43655f8cb2ef9afa759706ce5
https://doi.org/10.1016/j.canlet.2014.11.010
https://doi.org/10.1016/j.canlet.2014.11.010
Autor:
Anke Witting, Sarah Jesse, Karmveer Singh, Sebastian Iben, Silke Malmsheimer, Patrick Weydt, Uwe Schumann, Francesca Tuorto, Martina Zügel, Karin Scharffetter-Kochanek, Albert C. Ludolph, Jürgen M. Steinacker, Hanna Bayer, Marius Costel Alupei, Medhanie A. Mulaw
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
PGC-1α is a versatile inducer of mitochondrial biogenesis and responsive to the changing energy demands of the cell. As mitochondrial ATP production requires proteins that derive from translation products of cytosolic ribosomes, we asked whether PGC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c295d4bdb9d95fc3739dd3fbf77e41
https://doi.org/10.1038/s41598-017-09148-7
https://doi.org/10.1038/s41598-017-09148-7
Autor:
Marius Costel Alupei, Maximilian Wagner, Omar Garcia Gonzalez, Robin Assfalg, Adrian Schelling, Sebastian Iben, Sylvia Koch, Karin Scharffetter-Kochanek
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179843 (2017)
PLoS ONE
PLoS ONE
The nucleolus has long been considered to be a pure ribosome factory. However, over the last two decades it became clear that the nucleolus is involved in numerous other functions besides ribosome biogenesis. Our experiments indicate that the activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c41e36f17f96176f85ee537b8344335
http://europepmc.org/articles/PMC5479586?pdf=render
http://europepmc.org/articles/PMC5479586?pdf=render
Autor:
Lavinia Luca, Emilia Licarete, Marius Costel Alupei, Manuela Banciu, Ioan Tomuta, Marcela Achim, Alina Porfire, Laurian Vlase, Dana Muntean
Publikováno v:
Journal of Liposome Research. 25:261-269
Simvastatin (SIM) is a lipophilic statin that has potential benefits for prevention and treatment of several types of malignancies. However, its low water solubility and the toxicity associated with administration of high doses recommend it for encap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d403e321979d40d8c28598a711cbcab0
https://doi.org/10.3109/08982104.2014.987787
https://doi.org/10.3109/08982104.2014.987787
Publikováno v:
Anti-Cancer Drugs. 25:393-405
Statins, as inhibitors of de-novo synthesis of cholesterol, exert cytotoxic actions on tumor cells. Despite the increasing data on the antitumoral activities of statins, their complete mechanisms of action still remain obscure. Therefore, the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc9d030d310e4c39a5178bb6164fd80
https://doi.org/10.1097/cad.0000000000000065
https://doi.org/10.1097/cad.0000000000000065
Autor:
Karin Scharffetter-Kochanek, Marius Costel Alupei, Sebastian Iben, T. Phan, F. Khalid, Pallab Maity
Publikováno v:
Journal of Investigative Dermatology. 139:S269
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a594a2c83d8ba99acb5693daa5c8907
https://doi.org/10.1016/j.jid.2019.07.319
https://doi.org/10.1016/j.jid.2019.07.319
Autor:
Alina Sesarman, Alina Porfire, Dana-Maria Muntean, Lavinia Lupuţ, Laurian Vlase, Bianca Sylvester, Ioan Tomuţă, Manuela Banciu, Marius Costel Alupei, Emilia Licarete, Marcela Achim
Publikováno v:
ResearcherID
Quality by design principles (QbD) were used to assist the formulation of prednisolone-loaded long-circulating liposomes (LCL-PLP) in order to gain a more comprehensive understanding of the preparation process. This approach enables us to improve the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0859ecea58d68037373233847cf653de
https://pubmed.ncbi.nlm.nih.gov/27788618
https://pubmed.ncbi.nlm.nih.gov/27788618
Autor:
Laura Patras, Lavinia Luput, Emilia Licarete, Alina Sesarman, Marius Costel Alupei, Manuela Banciu
Publikováno v:
Oncology reports. 37(4)
The role of tumor-associated macrophages (TAMs) in the development of colon carcinoma is still controversial. Therefore, the present study aimed to investigate the TAM‑driven processes that may affect colon cancer cell proliferation. To achieve thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb57d4626dc74d212f0f339a47412fd7
https://pubmed.ncbi.nlm.nih.gov/28260079
https://pubmed.ncbi.nlm.nih.gov/28260079