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Publikováno v:
Journal of Pharmaceutical Sciences. 78:393-398
High-affinity (Ka = 3.0 X 10(8) M-1) monoclonal antidigoxin antibodies were covalently coupled to Sepharose CL-6B, Bio Gel A5m, Affi-gel 15, and agarose:polyacrolein microsphere (APAM) beads. Antibody immobilized to these supports was characterized i
Autor:
Marius Brizgys, Douglas E. Rollins
Publikováno v:
Annals of emergency medicine. 15(9)
The use of antibodies in the diagnosis and treatment of drug poisoning is becoming an important aspect of emergency medicine. Digoxin-specific antibodies selectively inhibit the pharmacologic and toxic effects of the digitalis glycosides. Digoxin-spe