Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Marius, Widerøe"'
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225788 (2019)
Melatonin has potential neuroprotective capabilities after neonatal hypoxia-ischemia (HI), but long-term effects have not been investigated. We hypothesized that melatonin treatment directly after HI could protect against early and delayed brain inju
Externí odkaz:
https://doaj.org/article/ab6c142a1ffd4226b45684173574af2e
Autor:
Hester Rijkje Berger, Axel K G Nyman, Tora Sund Morken, Riyas Vettukattil, Ann-Mari Brubakk, Marius Widerøe
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185202 (2017)
Melatonin is a promising neuroprotective agent after perinatal hypoxic-ischemic (HI) brain injury. We used in-vivo 1H magnetic resonance spectroscopy to investigate effects of melatonin treatment on brain metabolism after HI. Postnatal day 7 Sprague-
Externí odkaz:
https://doaj.org/article/e733552ead4045c7b9d3706b7d00e37f
Autor:
Francis, Mpambani, Andreas K O, Åslund, Frederic, Lerouge, Sofie, Nyström, Nina, Reitan, Else Marie, Huuse, Marius, Widerøe, Frederic, Chaput, Cyrille, Monnereau, Chantal, Andraud, Marc, Lecouvey, Susann, Handrick, Stefan, Prokop, Frank L, Heppner, Peter, Nilsson, Per, Hammarström, Mikael, Lindgren, Stephane, Parola
Publikováno v:
ACS applied bio materials. 1(2)
Real time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e5f5ce683d7996bd5b3dd3e48844e19
https://pubmed.ncbi.nlm.nih.gov/35016367
https://pubmed.ncbi.nlm.nih.gov/35016367
Autor:
Tora Sund Morken, Axel Karl Gottfrid Nyman, Ioanna Sandvig, Sverre Helge Torp, Jon Skranes, Pål Erik Goa, Ann-Mari Brubakk, Marius Widerøe
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/f01c8e8011b446b1bb91763e083a28e4
Autor:
Tora Sund Morken, Axel Karl Gottfrid Nyman, Ioanna Sandvig, Sverre Helge Torp, Jon Skranes, Pål Erik Goa, Ann-Mari Brubakk, Marius Widerøe
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84109 (2013)
Neonatal intermittent hyperoxia-hypoxia (IHH) is involved in the pathogenesis of retinopathy of prematurity. Whether similar oxygen fluctuations will create pathological changes in the grey and white matter of the brain is unknown.From birth until po
Externí odkaz:
https://doaj.org/article/f400f786d3524aa0b267142258929637
Autor:
Cláudia S F Queiroga, Simone Tomasi, Marius Widerøe, Paula M Alves, Alessandro Vercelli, Helena L A Vieira
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42632 (2012)
Perinatal hypoxia-ischemia is a major cause of acute mortality in newborns and cognitive and motor impairments in children. Cerebral hypoxia-ischemia leads to excitotoxicity and necrotic and apoptotic cell death, in which mitochondria play a major ro
Externí odkaz:
https://doaj.org/article/f24a17968855478fad5cf716ded0a8fe
Autor:
Einar Sulheim, Catharina de Lange Davies, Steinar Lundgren, Jana Kim, Marius Widerøe, David J. Waxman, Eugene Kim, Annemieke van Wamel, Sofie Snipstad, Ingeborg Hovde Grimstad, Sverre H. Torp, Igor Vidic
Publikováno v:
Journal of Controlled Release
King's College London
King's College London
Preclinical research has demonstrated that nanoparticles and macromolecules can accumulate in solid tumors due to the enhanced permeability and retention effect. However, drug loaded nanoparticles often fail to show increased efficacy in clinical tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d408bf863ce373019178cd0d90cd8466
https://doi.org/10.1016/j.jconrel.2018.04.026
https://doi.org/10.1016/j.jconrel.2018.04.026
Publikováno v:
Developmental Neuroscience. 39:36-48
Perinatal hypoxic-ischemic brain injury is a major health problem. Adjuvant treatments that improve the neuroprotective effect of the current treatment, therapeutic hypothermia, are urgently needed. The growing knowledge about the complex pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0609f28c9d385d86ccd09bdd0bebaf
https://doi.org/10.1159/000472709
https://doi.org/10.1159/000472709
Publikováno v:
Neurochemical Research. 42:115-132
Neonatal hypoxia-ischemia (HI) and the delayed injury cascade that follows involve excitotoxicity, oxidative stress and mitochondrial failure. The susceptibility to excitotoxicity of the neonatal brain may be related to the capacity of astrocytes for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d62488296e5f287c97d9de060c3f045
https://doi.org/10.1007/s11064-016-2149-9
https://doi.org/10.1007/s11064-016-2149-9
Autor:
Marius Widerøe, Sjoerd Hak, Axel Karl Gottfrid Nyman, Kåre Andre Kristiansen, Alexandros Marios Sofias, Alicja Molska
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 152
Melatonin is a neurohormone with potenial therapeutic effects in many diseases including neonatal hypoxic-ischemic (HI) brain injury. Due to limited solubility in water there is currently no clinically available melatonin formulation for parenteral u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66dfbb58f168aa2702b4498b30199e59
https://pubmed.ncbi.nlm.nih.gov/32439308
https://pubmed.ncbi.nlm.nih.gov/32439308