Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Maritza Puray-Chavez"'
Autor:
Maritza Puray-Chavez, Jenna E. Eschbach, Ming Xia, Kyle M. LaPak, Qianzi Zhou, Ria Jasuja, Jiehong Pan, Jian Xu, Zixiang Zhou, Shawn Mohammed, Qibo Wang, Dana Q. Lawson, Sanja Djokic, Gaopeng Hou, Siyuan Ding, Steven L. Brody, Michael B. Major, Dennis Goldfarb, Sebla B. Kutluay
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Host factors that define the cellular tropism of SARS-CoV-2 beyond the cognate ACE2 receptor are poorly defined. Here we report that SARS-CoV-2 replication is restricted at a post-entry step in a number of ACE2-positive airway-derived cell l
Externí odkaz:
https://doaj.org/article/941914b9381f4ed29c36d7cbcb886821
Autor:
Jenna E. Eschbach, Maritza Puray-Chavez, Shawn Mohammed, Qiankun Wang, Ming Xia, Lin-Chen Huang, Liang Shan, Sebla B. Kutluay
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTA critical determinant for early post-entry events, the HIV-1 capsid (CA) protein forms the conical core when it rearranges around the dimeric RNA genome and associated viral proteins. Although mutations in CA have been reported to alter inna
Externí odkaz:
https://doaj.org/article/2257f061331a49e299f19ee799a0d2dc
Autor:
Qiru Zeng, Avan Antia, Luis Alberto Casorla-Perez, Maritza Puray-Chavez, Sebla B. Kutluay, Matthew A. Ciorba, Siyuan Ding
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, much effort has been dedicated to identifying effective antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A number of calpain inhibitors
Externí odkaz:
https://doaj.org/article/ea4945db2bf6456cb0f9f479f9a0b715
Autor:
Maritza Puray-Chavez, Nakyung Lee, Kasyap Tenneti, Yiqing Wang, Hung R. Vuong, Yating Liu, Amjad Horani, Tao Huang, Sean P. Gunsten, James B. Case, Wei Yang, Michael S. Diamond, Steven L. Brody, Joseph Dougherty, Sebla B. Kutluay
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes a number of strategies to modulate viral and host mRNA translation. Here, we used ribosome profiling in SARS-CoV-2-infected model cell lines and primary airway cells grown
Externí odkaz:
https://doaj.org/article/676d5a8350f546c5baeaa34cae4b2506
Autor:
Maritza Puray-Chavez, Kyle M. LaPak, Travis P. Schrank, Jennifer L. Elliott, Dhaval P. Bhatt, Megan J. Agajanian, Ria Jasuja, Dana Q. Lawson, Keanu Davis, Paul W. Rothlauf, Zhuoming Liu, Heejoon Jo, Nakyung Lee, Kasyap Tenneti, Jenna E. Eschbach, Christian Shema Mugisha, Emily M. Cousins, Erica W. Cloer, Hung R. Vuong, Laura A. VanBlargan, Adam L. Bailey, Pavlo Gilchuk, James E. Crowe, Jr., Michael S. Diamond, D. Neil Hayes, Sean P.J. Whelan, Amjad Horani, Steven L. Brody, Dennis Goldfarb, M. Ben Major, Sebla B. Kutluay
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109364- (2021)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) variants govern transmissibility, responsiveness to vaccination, and disease severity. In a screen for new models of SARS-CoV-2 infection, we identify human H522 lung ade
Externí odkaz:
https://doaj.org/article/fd7ca3003b0d4b6e81dd2ed8d532da99
Autor:
Alicia Martinez-Lopez, Mirjana Persaud, Maritza Puray Chavez, Hongjie Zhang, Lijun Rong, Shufeng Liu, Tony T. Wang, Stefan G. Sarafianos, Felipe Diaz-Griffero
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 269-283 (2019)
Background: Flaviviruses such as Zika cause sporadic pandemic outbreaks worldwide. There is an urgent need for anti-Zika virus (ZIKV) drugs to prevent mother-to-child transmission of ZIKV, new infections in high-risk populations, and the infection of
Externí odkaz:
https://doaj.org/article/c501f0f7912b4b21a318e5ad574195a1
Autor:
Christian Shema Mugisha, Hung R. Vuong, Maritza Puray-Chavez, Adam L. Bailey, Julie M. Fox, Rita E. Chen, Alex W. Wessel, Jason M. Scott, Houda H. Harastani, Adrianus C. M. Boon, Haina Shin, Sebla B. Kutluay
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected millions within just a few months, causing severe respiratory disease and mortality. Assays to monitor SARS-CoV-2 growth in vitro depend on time-consuming and costly R
Externí odkaz:
https://doaj.org/article/5fa8bcf9f0bd472e90df2dc12e6e4f5e
Autor:
Jennifer L Elliott, Jenna E Eschbach, Pratibha C Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q Lawson, Alan N Engelman, Mamuka Kvaratskhelia, Sebla B Kutluay
Publikováno v:
eLife, Vol 9 (2020)
A large number of human immunodeficiency virus 1 (HIV-1) integrase (IN) alterations, referred to as class II substitutions, exhibit pleiotropic effects during virus replication. However, the underlying mechanism for the class II phenotype is not know
Externí odkaz:
https://doaj.org/article/fc785895057f4094b8a248a31422ab37
Autor:
Maritza Puray-Chavez, Philip R. Tedbury, Andrew D. Huber, Obiaara B. Ukah, Vincent Yapo, Dandan Liu, Juan Ji, Jennifer J. Wolf, Alan N. Engelman, Stefan G. Sarafianos
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Technical limitations in simultaneous microscopic visualization of HIV transcription from individual integration sites have curtailed progress in the field. Here the authors report a branched DNA in situ hybridization method for direct single-cell vi
Externí odkaz:
https://doaj.org/article/1c1971c8f6e44462b70f027522cf0fa9
Autor:
Isabella T. Whitworth, Rachel A. Knoener, Maritza Puray-Chavez, Peter Halfmann, Sofia Romero, M’bark Baddouh, Mark Scalf, Yoshihiro Kawaoka, Sebla B. Kutluay, Lloyd M. Smith, Nathan M. Sherer
Publikováno v:
bioRxiv
Host RNA binding proteins recognize viral RNA and play key roles in virus replication and antiviral defense mechanisms. SARS-CoV-2 generates a series of tiered subgenomic RNAs (sgRNAs), each encoding distinct viral protein(s) that regulate different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d44edf73bf5141068a6f3782e7c5c45a
https://europepmc.org/articles/PMC10245570/
https://europepmc.org/articles/PMC10245570/
