Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marites T. Woon"'
Autor:
Marites T. Woon, Pamela A. Long, Louise Reilly, Jared M. Evans, Alexis M. Keefe, Martin R. Lea, Carl J. Beglinger, Ravi C. Balijepalli, Youngsook Lee, Timothy M. Olson, Timothy J. Kamp
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 3 (2018)
BackgroundGenetic causes of dilated cardiomyopathy (DCM) are incompletely understood. LRRC10 (leucine‐rich repeat–containing 10) is a cardiac‐specific protein of unknown function. Heterozygous mutations in LRRC10 have been suggested to cause DC
Externí odkaz:
https://doaj.org/article/52b0263920c94d91858af49967d63279
Autor:
Marites T Woon, Timothy J Kamp
Publikováno v:
eLife, Vol 6 (2017)
Personalized heart muscle cells made from stem cells in the laboratory could be used to check an individual’s response to potential new drugs before clinical trials.
Externí odkaz:
https://doaj.org/article/7e9be7164b3d46e8bd4dec14ab85eec2
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2436
Bioreactor technolology enables the expansion of mammalian cells, which can be translated to processes compatible with Current Good Manufacturing Practice (cGMP) regulations. Cells are introduced to the bioreactor vessel, wherein key parameters such
Autor:
Alexey V. Glukhov, Walatta T. Mesquitta, Jabe M. Best, Kevin P. Vincent, Marites T. Woon, Jason D. Foell, Andrew D. McCulloch, Timothy J. Kamp, Leonid Tyan, Di Lang, Ravi C. Balijepalli, Michael J. Ackerman
Publikováno v:
The Journal of Physiology. 597:1531-1551
Key points Mutations in the caveolae scaffolding protein, caveolin-3 (Cav3), have been linked to the long QT type 9 inherited arrhythmia syndrome (LQT9) and the cause of underlying action potential duration prolongation is incompletely understood. In
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620175
Bioreactor technolology enables the expansion of mammalian cells, which can be translated to processes compatible with Current Good Manufacturing Practice (cGMP) regulations. Cells are introduced to the bioreactor vessel, wherein key parameters such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c31f2ea40c2c715c7c16bebd7b1160
https://doi.org/10.1007/7651_2021_396
https://doi.org/10.1007/7651_2021_396
Autor:
Eytan Abraham, Inbar Friedrich Ben-Nun, Nicholas Uth, Puspa R. Pandey, Igor Ngabo, Yonatan Levinson, Haritha Vallabhaneni, Marites T. Woon, Amarel Tomney, Farjad Shafighi
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 1
Volume 21
Issue 1
Industrialization of stem-cell based therapies requires innovative solutions to close the gap between research and commercialization. Scalable cell production platforms are needed to reliably deliver the cell quantities needed during the various stag
Autor:
Wendy C. Crone, Adriana M. Rodriguez, Timothy J. Kamp, William J. Burlingham, Wenxuan Cai, Luke Profio, Mitch Biermann, Brett N. Napiwocki, Matthew E. Brown, Dona Greta Isai, Di Lang, Tianxiao Han, Ying Ge, Annie Shao, Marites T. Woon, Jack Hermsen, Alexey V. Glukhov, Timothy A. Hacker, Donglim Esther Park, Ying Zhou, Andras Czirok
Publikováno v:
Stem Cells
Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) exhibit a fetal phenotype that limits in vitro and therapeutic applications. Strategies to promote cardiomyocyte maturation have focused interventions on differentiated hPSC-CMs, but this
Autor:
Leonid, Tyan, Jason D, Foell, Kevin P, Vincent, Marites T, Woon, Walatta T, Mesquitta, Di, Lang, Jabe M, Best, Michael J, Ackerman, Andrew D, McCulloch, Alexey V, Glukhov, Ravi C, Balijepalli, Timothy J, Kamp
Publikováno v:
The Journal of physiology. 597(6)
KEY POINTS: Mutations in the caveolae scaffolding protein, caveolin‐3 (Cav3), have been linked to the long QT type 9 inherited arrhythmia syndrome (LQT9) and the cause of underlying action potential duration prolongation is incompletely understood.
Autor:
Ravi C. Balijepalli, Youngsook Lee, Marites T. Woon, Martin R. Lea, Jared M. Evans, Timothy M. Olson, Alexis M Keefe, Pamela A. Long, Louise Reilly, Carl J. Beglinger, Timothy J. Kamp
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Genetic causes of dilated cardiomyopathy (DCM) are incompletely understood. LRRC10 (leucine‐rich repeat–containing 10) is a cardiac‐specific protein of unknown function. Heterozygous mutations in LRRC10 have been suggested to cause D
Autor:
Marites T Woon, Pamela A Long, Louise Reilly, Jared M Evans, Alexis M Keefe, Martin R Lea, Carl J Beglinger, Ravi C Balijepalli, Youngsook Lee, Timothy M Olson, Timothy J Kamp
Publikováno v:
Circulation Research. 121
Leucine-rich repeat containing (LRR) proteins facilitate protein-protein interactions critical in a number of cellular functions including ion channel regulation. Leucine-rich repeat containing protein 10 (LRRC10), a cardiac-specific protein expresse