Výsledky vyhledávání - "Marita Wasner"

Physicochemical and Biochemical Properties of 2‘,5‘-Linked RNA and 2‘,5‘-RNA:3‘,5‘-RNA 'Hybrid' Duplexes

Autor: Michael A. Parniak, Marita Wasner, Anne M. Noronha, Masad J. Damha, Gadi Borkow, Dominique Arion, Andre H. Uddin

Publikováno v: Biochemistry. 37:7478-7486

In recent publications, oligonucleotides joined by 2',5'-linkages were found to bind to complementary single-stranded RNA but to bind weakly, or not at all, to single-stranded DNA [e.g., P. A. Giannaris and M. J. Damha (1993) Nucleic Acids Res. 21, 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b276b09525ddf8bbc14d34c372952be2
https://doi.org/10.1021/bi980160b

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Nucleotides. Part LIII. 6-Aminohexanoyl-linked conjugates of monomeric and trimeric cordycepin

Autor: Ning Kon, Susan E. Horvath, Earl E. Henderson, Marita Wasner, Wolfgang Pfleiderer, Mingxu Guan, Robert J. Suhadolnik, Martin E. Adelson

Publikováno v: Helvetica Chimica Acta. 80:1061-1072

To improve cell permeability, monomeric 3′-deoxyadenosine (cordycepin) and antivirally active trimeric 3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenosine (2′–5′)d3 (A-A-A); (cordycepin-trimer core) were modi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3b747f804891d0f9ed18769a56d58c2
https://doi.org/10.1002/hlca.19970800405

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Nucleotides. Part IL. Synthesis and Characterization of Cordycepin-Trimer-Vitamin and -Lipid Conjugates Potential Inhibitors of HIV-1 Replication

Autor: Marita Wasner, Wolfgang Pfleiderer, Robert J. Suhadolnik, Susan E. Horvath, Ning Kon, Ming-Xu Guan, Earl E. Henderson, Martin E. Adelson

Publikováno v: Helvetica Chimica Acta. 79:619-633

The syntheses of biodegradable 2′- and 5′ -ester and 2′- and 5′ -carbonate conjugates of the antivirally active 3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenosine (cordycepin-trimer core) with the vitamins,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90c383e78f0816cc24b328bee3b38746
https://doi.org/10.1002/hlca.19960790305

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Nucleosides. Part LX. Synthesis and Characterization of Monomeric Cordycepin-Vitamin and Cordycepin-Lipid Conjugates Model Substances for Biodegradable Ester and Carbonate Linkages in Conjugates and Potential Inhibitors of HIV-1 Replication

Autor: Marita Wasner, Wolfgang Pfleiderer, Robert J. Suhadolnik, Susan E. Horvath, Ning Kon, Ming-Xu Guan, Earl E. Henderson, Martin E. Adelson

Publikováno v: Helvetica Chimica Acta. 79:609-618

Monomeric 3′-deoxyadenosine (cordycepin) was modified at the 2′-O- (13–18) and 5′-O-position (25–29) by the vitamins E, D2, and A and by the two lipids 1,2-di-O-palmitoylglycerol and 1,2-di-O-hexadecylglycerol via succinate or carbonate lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96441e405d184ce439059a6152bf29f2
https://doi.org/10.1002/hlca.19960790304

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Synthesis of Trimeric Cordycepin-Vitamin Conjugates as Improved Antiviral Agents

Autor: Wolfgang Pfleiderer, Marita Wasner

Publikováno v: Nucleosides, Nucleotides and Nucleic Acids. 14:1101-1104

The chemical syntheses of various cordycepin trimers carrying vitamin E, D2 and A via a succinate linker at the 2′-O- and 5′-O-position are described. The conjugates were characterized by physical means and used for biological investigations.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::985ed6db5ddd58b8a2e3081bc2bd2a13
https://doi.org/10.1080/15257779508012544

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Nucleotides. Part XLIV. Synthesis, characterization, and biological activity of monomeric and trimeric cordycepin-cholesterol conjugates and inhibition of HIV-1 replication

Autor: Marita Wasner, Earl E. Henderson, Robert J. Suhadolnik, Wolfgang Pfleiderer

Publikováno v: Helvetica Chimica Acta. 77:1757-1767

The antivirally active 3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenylyl-(2′–5′)-3′-deoxyadenosine (cordycepin trimer core) was modified at the 2′- or 5′-terminus, by attachment of cholesterol via a carbonate bond ( 15) or a succinate l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df4e5d538327444e528b2fee11e68bad
https://doi.org/10.1002/hlca.19940770707

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Syntheses and characterization of cholesteryl conjugates in 2'-O- and 5'-O-position of cordycepin trimer

Autor: Marita Wasner, Wolfgang Pfleiderer

Publikováno v: Collection of Czechoslovak Chemical Communications. 58:146-149

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4441bc72fa87e44f073d6366972feec6
https://doi.org/10.1135/cccc1993s146

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ChemInform Abstract: Nucleotides. Part 44. Synthesis, Characterization, and Biological Activity of Monomeric and Trimeric Cordycepin-Cholesterol Conjugates and Inhibition of HIV-1 Replication

Autor: R. J. Suhadolnik, E. E. Henderson, Wolfgang Pfleiderer, Marita Wasner

Publikováno v: ChemInform. 26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::251a32baf1334f224fe04b937e83be37
https://doi.org/10.1002/chin.199514287

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ChemInform Abstract: Nucleotides. Part 53. 6-Aminohexanoyl-Linked Conjugates of Monomeric and Trimeric Cordycepin

Autor: N. Kon, R. J. Suhadolnik, Marita Wasner, M.‐X. Guan, Wolfgang Pfleiderer, E. E. Henderson, S. E. Horvath, M. E. Adelson

Publikováno v: ChemInform. 28

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c69e298cc6d53262b92a46895398d7b2
https://doi.org/10.1002/chin.199737256

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