Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marita J. Walmsley"'
Autor:
Tyler Jacks, Victor L.J. Tybulewicz, Anthony J. Capobianco, David A. Tuveson, Matthew S. Eckman, Alejandro Sweet-Cordero, Carla F. Bender Kim, Kevin M. Haigis, Linda Hanlon, Marita J. Walmsley, Joseph L. Kissil
Supplementary Figure 1 from Requirement for Rac1 in a K-ras–Induced Lung Cancer in the Mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1f9d983ad257e8734f8ca39a8407f6
https://doi.org/10.1158/0008-5472.22367508.v1
https://doi.org/10.1158/0008-5472.22367508.v1
Autor:
Tyler Jacks, Victor L.J. Tybulewicz, Anthony J. Capobianco, David A. Tuveson, Matthew S. Eckman, Alejandro Sweet-Cordero, Carla F. Bender Kim, Kevin M. Haigis, Linda Hanlon, Marita J. Walmsley, Joseph L. Kissil
Given the prevalence of Ras mutations in human cancer, it is critical to understand the effector pathways downstream of oncogenic Ras leading to transformation. To directly assess the requirement for Rac1 in K-ras–induced tumorigenesis, we employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a64da1874672719bc39d1f484f7a46
https://doi.org/10.1158/0008-5472.c.6495576
https://doi.org/10.1158/0008-5472.c.6495576
Autor:
Sebastian Amigorena, Victor L. J. Tybulewicz, Federica Benvenuti, Michel R. Popoff, Sandra Ruf, Luc Fetler, Stéphanie Hugues, Marita J. Walmsley
Publikováno v:
Science. 305:1150-1153
Upon maturation, dendritic cells (DCs) acquire the unique ability to activate naïve T cells. We used time-lapse video microscopy and two-photon imaging of intact lymph nodes to showthat after establishing initial contact between their dendrites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7e4e9f94d8067bc25f1fe153cb9753
https://doi.org/10.1126/science.1099159
https://doi.org/10.1126/science.1099159
Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration
Publikováno v:
Journal of Cell Science. 117:1259-1268
Rac GTPases are activated by extracellular stimuli and contribute to cellular responses including cytoskeletal changes and cell migration. Dominant-negative Rac1 has been used to implicate Rac GTPases in these responses, but which of the three mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9c35f693916435bc94830280c510da
https://doi.org/10.1242/jcs.00997
https://doi.org/10.1242/jcs.00997
Autor:
Steen K.T. Ooi, David A. Williams, Lesley Vanes, Susan Harless Smith, Michael P. Cancro, Lucinda F. Reynolds, Anne Mathiot, Victor L. J. Tybulewicz, Sandra Ruf, Marita J. Walmsley
Publikováno v:
Science. 302:459-462
The Rac1 guanosine triphosphatase (GTPase) has been implicated in multiple cellular functions, including actin dynamics, proliferation, apoptosis, adhesion, and migration resulting from signaling by multiple receptors, including the B cell antigen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b44b6639763efac56d99d1bdfbea97f
https://doi.org/10.1126/science.1089709
https://doi.org/10.1126/science.1089709
Autor:
Matthew S. Eckman, Victor L. J. Tybulewicz, Kevin M. Haigis, Tyler Jacks, Anthony J. Capobianco, Joseph L. Kissil, Marita J. Walmsley, Alejandro Sweet-Cordero, David A. Tuveson, Linda Hanlon, Carla F. Kim
Publikováno v:
Cancer research. 67(17)
Given the prevalence of Ras mutations in human cancer, it is critical to understand the effector pathways downstream of oncogenic Ras leading to transformation. To directly assess the requirement for Rac1 in K-ras–induced tumorigenesis, we employed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd7c817e0d4db550e82767fb5513c7e
https://pubmed.ncbi.nlm.nih.gov/17804720
https://pubmed.ncbi.nlm.nih.gov/17804720