Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Marita, Cohn"'
Publikováno v:
eLife, Vol 11 (2022)
Rap1 is the main protein that binds double-stranded telomeric DNA in Saccharomyces cerevisiae. Examination of the telomere functions of Rap1 is complicated by the fact that it also acts as a transcriptional regulator of hundreds of genes and is encod
Externí odkaz:
https://doaj.org/article/b91212b501214980ad575916b57b23ca
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 10, Pp 3345-3358 (2019)
The enzyme telomerase ensures the integrity of linear chromosomes by maintaining telomere length. As a hallmark of cancer, cell immortalization and unlimited proliferation is gained by reactivation of telomerase. However, a significant fraction of ca
Externí odkaz:
https://doaj.org/article/f1bcd6566b8f44cab7d61b4292e14ee2
Rap1 and Cdc13 have complementary roles in preventing exonucleolytic degradation of telomere 5′ ends
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Telomere DNA ends with a single-stranded 3′ overhang. Long 3′ overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated se
Externí odkaz:
https://doaj.org/article/ea94b149eb7b4623a8c3eeb2d766981c
Publikováno v:
eLife. ELIFE SCIENCES PUBLICATIONS LTD
eLife, Vol 11 (2022)
eLife, Vol 11 (2022)
Rap1 is the main protein that binds double-stranded telomeric DNA in Saccharomyces cerevisiae. Examination of the telomere functions of Rap1 is complicated by the fact that it also acts as a transcriptional regulator of hundreds of genes and is encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9b864d91a33c2fda9bd8cc9901f750
https://doi.org/10.7554/elife.74090
https://doi.org/10.7554/elife.74090
Autor:
Fernando Rodrigo, Rosas Bringas, Sonia, Stinus, Pien, de Zoeten, Marita, Cohn, Michael, Chang
Publikováno v:
eLife
Rap1 is the main protein that binds double-stranded telomeric DNA in Saccharomyces cerevisiae. Examination of the telomere functions of Rap1 is complicated by the fact that it also acts as a transcriptional regulator of hundreds of genes and is encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d59f230269cce4799ceb91faefa76ea8
https://pubmed.ncbi.nlm.nih.gov/35044907
https://pubmed.ncbi.nlm.nih.gov/35044907
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Telomeres, the DNA-protein structures capping the ends of linear chromosomes, are important for regulating replicative senescence and maintaining genome stability. Telomeres consist of G-rich repetitive sequences that end in a G-rich single-stranded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5482876ea7ef4d7ea21357ea6eea600a
http://europepmc.org/articles/PMC6915718
http://europepmc.org/articles/PMC6915718
Autor:
Ahu Karademir Andersson, Marita Cohn
Publikováno v:
Yeast. 34:95-109
Naumovozyma castellii (Saccharomyces castellii) is a member of the budding yeast family Saccharomycetaceae. It has been extensively used as a model organism for telomere biology research and has gained an increasing interest as a budding yeast model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4e4841c045704c7e316f382c6c8d730
https://doi.org/10.1002/yea.3218
https://doi.org/10.1002/yea.3218
Publikováno v:
Yeast. 33:633-646
The budding yeast Naumovozyma castellii (syn. Saccharomyces castellii) has been included in comparative genomics studies, functional analyses of centromere DNA elements, and was shown to possess beneficial traits for telomere biology research. To pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85bb0bc2c566c518190148e9eac8cedd
https://doi.org/10.1002/yea.3213
https://doi.org/10.1002/yea.3213
Publikováno v:
Journal of molecular biology. 429(14)
Telomerase maintains telomere length and chromosome integrity by adding short tandem repeats of single-stranded DNA to the 3' ends, via reverse transcription of a defined template region of its RNA subunit. To further understand the telomerase elonga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c31fe2c2362ba884d4d55e5645321ab
https://pubmed.ncbi.nlm.nih.gov/28483647
https://pubmed.ncbi.nlm.nih.gov/28483647