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Autor:
Alexandra Gerogianni, Laura M. Baas, Dick J. Sjöström, Nicole C. A. J. van de Kar, Marit Pullen, Siem J. van de Peppel, Per H. Nilsson, Lambertus P. van den Heuvel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Factor I (FI) is an essential regulator of the complement system. Together with co-factors, FI degrades C3b, which inhibits further complement activation. Genetic mutations in FI are associated with pathological conditions like age-related macular de
Externí odkaz:
https://doaj.org/article/8c1fc88df0f24e1aa4fbde43618f12be