Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marit Ledsaak"'
Autor:
Roza Berhanu Lemma, Thomas Fleischer, Emily Martinsen, Marit Ledsaak, Vessela Kristensen, Ragnhild Eskeland, Odd Stokke Gabrielsen, Anthony Mathelier
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-19 (2022)
Abstract Methylation of cytosines on DNA is a prominent modification associated with gene expression regulation. Aberrant DNA methylation patterns have recurrently been linked to dysregulation of the regulatory program in cancer cells. To shed light
Externí odkaz:
https://doaj.org/article/466cc2aaf5ba4b33ae516078661b0b78
Autor:
Roza B. Lemma, Marit Ledsaak, Bettina M. Fuglerud, Geir Kjetil Sandve, Ragnhild Eskeland, Odd S. Gabrielsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much
Externí odkaz:
https://doaj.org/article/aff4d035089f405cb2b6a55119ff4841
Publikováno v:
FEBS Open Bio, Vol 10, Iss 11, Pp 2329-2342 (2020)
Transcription factors use a DNA‐binding domain to localize their action and a transactivation domain (tAD) to stimulate activation of the associated gene. Recent work has renewed interest in how tADs activate genes, which remains poorly understood.
Externí odkaz:
https://doaj.org/article/1cac13089d3c4a71b63ea4d984bd5591
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and differentiation. However, the precise molecular mechanism underlying pioneer fact
Externí odkaz:
https://doaj.org/article/517c5a6b37424159a06ae7037d383c04
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 10, Iss 11, Pp 2329-2342 (2020)
FEBS Open Bio, Vol 10, Iss 11, Pp 2329-2342 (2020)
Genes are activated by transcription factors through their transactivation domains (tADs); disordered regions that have been poorly understood. New models for tADs have recently been proposed. Here, these models were assessed through a mutational ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d41ae16b1fba18a4a80fded5225e52d
https://doi.org/10.1002/2211-5463.12978
https://doi.org/10.1002/2211-5463.12978
Autor:
Roza Berhanu Lemma, Thomas Fleischer, Emily Martinsen, Marit Ledsaak, Vessela Kristensen, Ragnhild Eskeland, Odd Stokke Gabrielsen, Anthony Mathelier
Publikováno v:
Epigeneticschromatin. 15(1)
Methylation of cytosines on DNA is a prominent modification associated with gene expression regulation. Aberrant DNA methylation patterns have recurrently been linked to dysregulation of the regulatory program in cancer cells. To shed light on the un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f75d72fdcd1c5596f37a30a3b0e46c2
https://pubmed.ncbi.nlm.nih.gov/35440061
https://pubmed.ncbi.nlm.nih.gov/35440061
Autor:
Marit Ledsaak, Roza Berhanu Lemma, Odd S. Gabrielsen, Bettina M. Fuglerud, Ragnhild Eskeland, Geir Kjetil Sandve
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much accumulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176d294cfefeeb56410cb22bf99af4ac
http://europepmc.org/articles/PMC8076236
http://europepmc.org/articles/PMC8076236
Autor:
Mads Bengtsen, Marit Ledsaak, Odd S. Gabrielsen, Lisa Marie Moen, Fernando Rodríguez-Castañeda, Ragnhild Eskeland, Ignacio Cuervo, Roza Berhanu Lemma
Publikováno v:
Journal of Biological Chemistry. 293:15439-15454
The small ubiquitin-like modifier (SUMO) post-translationally modifies lysine residues of transcription factors and co-regulators and thereby contributes to an important layer of control of the activities of these transcriptional regulators. Likewise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435ee9ff3a3ee0166db6034e82e4d003
https://doi.org/10.1074/jbc.ra118.002844
https://doi.org/10.1074/jbc.ra118.002844
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and differentiation. However, the precise molecular mechanism underlying pioneer factor activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8b7728b9437ca7cdca2220393904c4
https://doi.org/10.1186/s13072-018-0208-y
https://doi.org/10.1186/s13072-018-0208-y
Autor:
Vilborg Matre, Mads Bengtsen, Marit Ledsaak, Linda Therese Sørensen, Linn Ingeborg Aabel, Odd S. Gabrielsen
LIM-domain proteins, containing multiple cysteine-rich zinc finger-like motifs, have been shown to play diverse roles in several cellular processes. A common theme is that they mediate important protein-protein interactions that are key to their func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975e8844ef02c9732aee393d28055656
http://hdl.handle.net/10852/64170
http://hdl.handle.net/10852/64170
