Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Marit J. VAN GILS"'
Autor:
Steven W. de Taeye, Angela I. Schriek, Jeffrey C. Umotoy, Marloes Grobben, Judith A. Burger, Rogier W. Sanders, Gestur Vidarsson, Manfred Wuhrer, David Falck, Neeltje A. Kootstra, Marit J. van Gils
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) have the capacity to delay viral rebound when administered to people with HIV-1 (PWH) during anti-retroviral therapy (ART) interruption. To further enhan
Externí odkaz:
https://doaj.org/article/bd55cd58e2634a59b51fc88dc6c76b5f
Autor:
Daria Balashova, Barbera D. C. van Schaik, Maria Stratigopoulou, Jeroen E. J. Guikema, Tom G. Caniels, Mathieu Claireaux, Marit J. van Gils, Anne Musters, Dornatien C. Anang, Niek de Vries, Victor Greiff, Antoine H. C. van Kampen
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-22 (2024)
Abstract The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it responds to antigens. The BCR repertoire of an individual is formed throughout lif
Externí odkaz:
https://doaj.org/article/4721851a60424610a3e66446a8304cfe
Autor:
Mitch Brinkkemper, Meliawati Poniman, Esther Siteur-van Rijnstra, Widad Ait Iddouch, Tom P.L. Bijl, Denise Guerra, Khadija Tejjani, Marloes Grobben, Farien Bhoelan, Denzel Bemelman, Ronald Kempers, Marit J. van Gils, Kwinten Sliepen, Toon Stegmann, Yme U. van der Velden, Rogier W. Sanders
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109719- (2024)
Summary: Zoonotic events by sarbecoviruses have sparked an epidemic (severe acute respiratory syndrome coronavirus [SARS-CoV]) and a pandemic (SARS-CoV-2) in the past two decades. The continued risk of spillovers from animals to humans is an ongoing
Externí odkaz:
https://doaj.org/article/d7e94e034de54733ba21aac6f170e6e9
Autor:
Leanne P. M. van Leeuwen, Marloes Grobben, Corine H. GeurtsvanKessel, Pauline M. Ellerbroek, Godelieve J. de Bree, Judith Potjewijd, Abraham Rutgers, Hetty Jolink, Frank L. van de Veerdonk, Marit J. van Gils, Rory D. de Vries, Virgil A. S. H. Dalm, VACOPID Research Group, Eric C.M. van Gorp, Faye de Wilt, Susanne Bogers, Lennert Gommers, Daryl Geers, Marianne W. van der Ent, P. Martin van Hagen, Jelle W. van Haga, Bregtje A. Lemkes, Annelou van der Veen, Rogier W. Sanders, Karlijn van der Straten, Judith A. Burger, Jacqueline van Rijswijk, Khadija Tejjani, Joey H. Bouhuijs, Karina de Leeuw, Annick A.J.M. van de Ven, S.F.J. de Kruijf-Bazen, Pieter van Paassen, Lotte Wieten, Petra H. Verbeek-Menken, Annelies van Wengen, Anke H.W. Bruns, Helen L. Leavis, Stefan Nierkens
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposePrevious studies have demonstrated that the majority of patients with an inborn error of immunity (IEI) develop a spike (S)-specific IgG antibody and T-cell response after two doses of the mRNA-1273 COVID-19 vaccine, but little is known about
Externí odkaz:
https://doaj.org/article/f5f340a3b6454dfba93ece08a8ba7d1f
Autor:
Liridona Maliqi, Nikolas Friedrich, Matthias Glögl, Stefan Schmutz, Daniel Schmidt, Peter Rusert, Merle Schanz, Maryam Zaheri, Chloé Pasin, Cyrille Niklaus, Caio Foulkes, Thomas Reinberg, Birgit Dreier, Irene Abela, David Peterhoff, Alexandra Hauser, Roger D. Kouyos, Huldrych F. Günthard, Marit J. van Gils, Rogier W. Sanders, Ralf Wagner, Andreas Plückthun, Alexandra Trkola
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Understanding the balance between epitope shielding and accessibility on HIV-1 envelope (Env) trimers is essential to guide immunogen selection for broadly neutralizing antibody (bnAb) based vaccines. To investigate the antigenic space of En
Externí odkaz:
https://doaj.org/article/3c1b7ec8277b4efcb7d60e82c1710437
Autor:
Hongying Duan, Angela R. Corrigan, Cheng Cheng, Andrea Biju, Christopher A. Gonelli, Adam S. Olia, I-Ting Teng, Kai Xu, Sijy O’Dell, Sandeep Narpala, Mike Castro, Leonid Serebryannyy, Jennifer Wang, Danealle K. Parchment, Edward K. Sarfo, Jelle van Schooten, John-Paul Todd, Shuishu Wang, Darcy R. Harris, Hui Geng, Alexander J. Jafari, Ruth A. Woodward, Nicole A. Doria-Rose, Kathryn E. Foulds, Adrian B. McDermott, Marit J. van Gils, Richard A. Koup, Theodore C. Pierson, Peter D. Kwong, John R. Mascola
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108877- (2024)
Summary: Soluble ‘SOSIP’-stabilized HIV-1 envelope glycoprotein (Env) trimers elicit dominant antibody responses targeting their glycan-free base regions, potentially diminishing neutralizing responses. Previously, using a nonhuman primate model,
Externí odkaz:
https://doaj.org/article/bc8aa3b518694807a3c5228e93d29f17
Autor:
Joan Capella-Pujol, Marlon de Gast, Laura Radić, Ian Zon, Ana Chumbe, Sylvie Koekkoek, Wouter Olijhoek, Janke Schinkel, Marit J. van Gils, Rogier W. Sanders, Kwinten Sliepen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract An effective preventive vaccine for hepatitis C virus (HCV) remains a major unmet need. Antigenic region 3 (AR3) on the E1E2 envelope glycoprotein complex overlaps with the CD81 receptor binding site and represents an important epitope for b
Externí odkaz:
https://doaj.org/article/20fc85222ffc4339b25c15e9589db983
Autor:
Sanne J.M. Zilver, Christianne J.M. de Groot, Marloes Grobben, Sharon Remmelzwaal, Esmee Burgers, Daniela Nunez Velasco, Hannah G. Juncker, Britt J. van Keulen, Johannes B. van Goudoever, Robert A. de Leeuw, Marit J. van Gils, Carrie Ris-Stalpers, Elisabeth van Leeuwen
Publikováno v:
International Journal of Infectious Diseases, Vol 130, Iss , Pp 126-135 (2023)
Objectives: Preventive measures against COVID-19 are essential for pregnant women. Pregnant women are particularly vulnerable to emerging infectious pathogens due to alterations in their physiology. We aimed to determine the optimum timing of vaccina
Externí odkaz:
https://doaj.org/article/fd00055efb02450a8a7e1830e99d5223
Autor:
Rodrigo García-Valiente, Elena Merino Tejero, Maria Stratigopoulou, Daria Balashova, Aldo Jongejan, Danial Lashgari, Aurélien Pélissier, Tom G. Caniels, Mathieu A. F. Claireaux, Anne Musters, Marit J. van Gils, María Rodríguez Martínez, Niek de Vries, Michael Meyer-Hermann, Jeroen E. J. Guikema, Huub Hoefsloot, Antoine H. C. van Kampen
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Sequencing of B-cell and T-cell immune receptor repertoires helps us to understand the adaptive immune response, although it only provides information about the clonotypes (lineages) and their frequencies and not about, for example, their af
Externí odkaz:
https://doaj.org/article/44b6c99bb69541cc9cb23059ccbecc30
Autor:
Denise Guerra, Tim Beaumont, Laura Radić, Gius Kerster, Karlijn van der Straten, Meng Yuan, Jonathan L. Torres, Wen-Hsin Lee, Hejun Liu, Meliawati Poniman, Ilja Bontjer, Judith A. Burger, Mathieu Claireaux, Tom G. Caniels, Jonne L. Snitselaar, Tom P.L. Bijl, Sabine Kruijer, Gabriel Ozorowski, David Gideonse, Kwinten Sliepen, Andrew B. Ward, Dirk Eggink, Godelieve J. de Bree, Ian A. Wilson, Rogier W. Sanders, Marit J. van Gils
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108009- (2023)
Summary: The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has remained a medical threat due to the evolution of multiple variants that acquire resistance to vaccines and prior infection. Therefore, it is imperative
Externí odkaz:
https://doaj.org/article/3ad7176ab698474aa693e7f4597fd235