Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maristella, Colombo"'
Autor:
Daniele Donati, Andrea Lombardi Borgia, Ettore Perrone, Lucio Ceriani, Chiara Marchionni, Paolo Orsini, Marcella Nesi, Luisa Rusconi, Paola Magnaghi, Marina Fasolini, Nilla Avanzi, G. Canevari, Arturo Galvani, Maristella Colombo, Patrizia Banfi, Elena Ardini, Laura Buffa, Antonella Isacchi, Christian Orrenius, Roberto Bossi, Maria Beatrice Saccardo, Ermes Vanotti, Claudio Fiorelli, Francesco Fiorentini, Maria Menichincheri, Achille Panzeri, Luca Corti, Enrico Pesenti, Eduard R. Felder
Publikováno v:
Journal of Medicinal Chemistry. 59:3392-3408
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase responsible for the development of different tumor types. Despite the remarkable clinical activity of crizotinib (Xalkori), the first ALK inhibitor approved in 2011, the emergence of resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc806429f7d1f3155f365de5d16bf20
https://doi.org/10.1021/acs.jmedchem.6b00064
https://doi.org/10.1021/acs.jmedchem.6b00064
Autor:
Silvia, Pezzola, Giovanni, Antonini, Cristina, Geroni, Italo, Beria, Maristella, Colombo, Massimo, Broggini, Sergio, Marchini, Nicola, Mongelli, Loris, Leboffe, Robert, MacArthur, Alessia Francesca, Mozzi, Giorgio, Federici, Anna Maria, Caccuri
Publikováno v:
Biochemistry. 49:226-235
Brostallicin is a novel and unique glutathione transferase-activated pro-drug with promising anticancer activity, currently in phase I and II clinical evaluation. In this work, we show that, in comparison with the parental cell line showing low GST l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551619c23702171c412c9b997d576ee
https://doi.org/10.1021/bi901689s
https://doi.org/10.1021/bi901689s
Autor:
Giulio Vistoli, Giancarlo Aldini, Nicoletta Colombo, Jan Malyszko, Maristella Colombo, Federico Riccardi Sirtori, Roberto D'Alessio
Publikováno v:
ChemMedChem. 7:1112-1122
Postreplicative mismatch repair (MMR) is a cellular system involved in the recognition and correction of DNA polymerase errors that escape detection in proofreading. Of the various mismatched bases, T:G pairing in DNA is one of the more common mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e8f92119d891aa8365b146901ae7b9
https://doi.org/10.1002/cmdc.201100526
https://doi.org/10.1002/cmdc.201100526
Autor:
Heike Schäfer, Christiane Lohaus, Helmut E. Meyer, Katrin Marcus, Hans Bilke, Knut Wagner, Mario Arangio, Federico Riccardi Sirtori, Katia Marcucci, Giuseppe Razzano, Maristella Colombo, Roberto Biancardi, Vincenzo Rizzo
Publikováno v:
HPLC richtig optimiert. :651-726
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec23da247d31df9b7f2651fa72cc3929
https://doi.org/10.1002/9783527623525.ch5
https://doi.org/10.1002/9783527623525.ch5
Autor:
Claudio Dalvit, Carlo Visco, Federico Riccardi Sirtori, Gianpaolo Fogliatto, Maristella Colombo, Dannica Caronni, Mauro Paolucci, Luca Regazzoni
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 76
ESI-MS is a well established technique for the study of biopolymers (nucleic acids, proteins) and their non covalent adducts, due to its capacity to detect ligand-target complexes in the gas phase and allows inference of ligand-target binding in solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0a89cf077d0a41dd556e31b4cdcc2a
https://pubmed.ncbi.nlm.nih.gov/25952103
https://pubmed.ncbi.nlm.nih.gov/25952103
Autor:
Nilla Avanzi, Sabrina Cribioli, Paola Gnocchi, Jay Bertrand, Danilo Mirizzi, Daniele Casero, Arturo Galvani, Paola Vianello, Maristella Colombo, Eduard R. Felder, Gabriele Fachin, Achille Panzeri, Lucio Ceriani, G. Canevari, Franco Della Vedova, Dario Ballinari, Cinzia Cristiani, Enrico Pesenti, Marcella Nesi, Tiziano Bandiera, Marina Ciomei, Alessandra Cirla, Maria Gabriella Brasca, Antonella Isacchi, Daniele Donati, Ilaria Motto, Simona Bindi, Marina Fasolini, Davide Carenzi
Publikováno v:
Bioorganicmedicinal chemistry. 22(17)
We report herein the discovery, structure guided design, synthesis and biological evaluation of a novel class of JAK2 inhibitors. Optimization of the series led to the identification of the potent and orally bioavailable JAK2 inhibitor 28 (NMS-P953).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0c075da4c4b914848e8b7a2755d219
https://pubmed.ncbi.nlm.nih.gov/25009002
https://pubmed.ncbi.nlm.nih.gov/25009002
Autor:
Vittorio Pinciroli, Vincenzo Rizzo, Roberto Biancardi, and Maristella Colombo, Nicoletta Colombo
Publikováno v:
Journal of Combinatorial Chemistry. 3:434-440
A novel silane standard, 1,4-bis(trimethylsilyl)benzene (BTMSB), is introduced for the generic quantitation of small organic molecules in DMSO-d(6) solution by (1)H NMR. This standard is an easily weighable solid and is stable for at least 1 month in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18edf3f2c1c264dc3032e8f03225f889
https://doi.org/10.1021/cc000101t
https://doi.org/10.1021/cc000101t
Autor:
Maristella Colombo, E. Arlandini, Maria Menichincheri, Vittorio Pinciroli, Walter Ceccarelli, Nicola Mongelli, Ermes Vanotti, Domenico Fusar-Bassini, L Franzoi
Publikováno v:
Tetrahedron Letters. 38:3301-3304
Upon treatment of 7-triethylsilyl-10, 13-dideoxy-13-imino baccatin III ( 2 ) subsequently with diazomethane and m-chloroperbenzoic acid a few novel derivatives, namely methylimine 3 and oximes 4 and 5 , were obtained. Interestingly, 4 is characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13876959ebf810408e32e647d40c38fe
https://doi.org/10.1016/s0040-4039(97)00591-1
https://doi.org/10.1016/s0040-4039(97)00591-1
Publikováno v:
Phytochemical Analysis. 6:196-202
The determination of six different isoquinoline alkaloids from Chelidonium majus (leaves and roots) using capillary electrophoresis is described. Analyses were performed on fused silica capillaries with 66 mM phosphate buffer at pH 2.4 containing 40%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076e572960bd2acc8a56d34dba665e07
https://doi.org/10.1002/pca.2800060404
https://doi.org/10.1002/pca.2800060404
Publikováno v:
Tetrahedron Letters. 36:949-952
Samarium diiodide-mediated cyclizations of aryl radicals carried out in the presence of several nitrogen ligands(triethylamine, 1,8-diazabyciclo[5.4.0]undec-7-ene and 1,1-3,3-Tetramethylguanidine) are described. The yields and the selectivities obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55f411420d08d002d567bfebf8ac0b57
https://doi.org/10.1016/0040-4039(94)02398-u
https://doi.org/10.1016/0040-4039(94)02398-u