Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Marissa Wisman"'
1
Akademický článek
Dysregulated cross-talk between alveolar epithelial cells and stromal cells in idiopathic pulmonary fibrosis reduces epithelial regenerative capacity
Autor: Marissa Wisman, Mehmet Nizamoglu, Jacobien A. Noordhoek, Wim Timens, Janette K. Burgess, Irene H. Heijink
Publikováno v: Frontiers in Medicine, Vol 10 (2023)
In idiopathic pulmonary fibrosis (IPF) constant epithelial micro-injury and aberrant interactions within the stromal micro-environment lead to abnormal alveolar repair and fibrosis. We hypothesized that alveolar epithelial regenerative responses in I
Externí odkaz: https://doaj.org/article/cd370063ba214204a627d9caa69cbadd
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2
Akademický článek
Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells
Autor: Dennis M. L. W. Kruk, Marissa Wisman, Jacobien A. Noordhoek, Mehmet Nizamoglu, Marnix R. Jonker, Harold G. de Bruin, Karla Arevalo Gomez, Nick H. T. ten Hacken, Simon D. Pouwels, Irene H. Heijink
Publikováno v: Cells, Vol 10, Iss 11, p 2860 (2021)
COPD is characterized by irreversible lung tissue damage. We hypothesized that lung-derived mesenchymal stromal cells (LMSCs) reduce alveolar epithelial damage via paracrine processes, and may thus be suitable for cell-based strategies in COPD. We ai
Externí odkaz: https://doaj.org/article/c260538f10634f8fb47eb09a8a7cee22
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3
Th2 high and mast cell gene signatures are associated with corticosteroid sensitivity in COPD
Autor: Alen Faiz, Stelios Pavlidis, Chih-Hsi Kuo, Anthony Rowe, Pieter S Hiemstra, Wim Timens, Marijn Berg, Marissa Wisman, Yi-Ke Guo, Ratko Djukanović, Peter Sterk, Kerstin B Meyer, Martijn C Nawijn, Ian Adcock, Kian Fan Chung, Maarten van den Berge
Publikováno v: Thorax, 78:217736, 335-343. BMJ PUBLISHING GROUP
Thorax. BMJ PUBLISHING GROUP
Thorax
Thorax. BMJ Publishing Group
RationaleSevere asthma and chronic obstructive pulmonary disease (COPD) share common pathophysiological traits such as relative corticosteroid insensitivity. We recently published three transcriptome-associated clusters (TACs) using hierarchical anal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9659e5c1de14cf2701639381476a77eb
https://hdl.handle.net/1887/3565018
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4
Abnormalities in reparative function of lung-derived mesenchymal stromal cells in emphysema
Autor: Dennis Kruk, Harold G. de Bruin, Nick H. T. ten Hacken, Irene H. Heijink, Marissa Wisman, Toin H. van Kuppevelt, Janette K. Burgess, Wim Timens, Monique E. Lodewijk, Theo Borghuis, Danique J. Hof, Willeke F. Daamen
Publikováno v: American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, 5, pp. L832-L844
American Journal of Physiology-Lung Cellular and Molecular Physiology, 320(5), L832-L844. AMER PHYSIOLOGICAL SOC
American Journal of Physiology : Lung Cellular and Molecular Physiology, 320, L832-L844
Mesenchymal stromal cells (MSCs) may provide crucial support in the regeneration of destructed alveolar tissue (emphysema) in chronic obstructive pulmonary disease (COPD). We hypothesized that lung-derived MSCs (LMSCs) from patients with emphysema ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83274e106e727ec3401c6bf08967d530
https://research.rug.nl/en/publications/ab66799e-cdf9-4fd3-b58c-27e4ac91cd27
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6
Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells
Autor: Mehmet Nizamoglu, Marnix R. Jonker, Harold G. de Bruin, Simon D. Pouwels, Dennis M L W Kruk, Karla F. Arevalo Gomez, Marissa Wisman, Jacobien A. Noordhoek, Nick H. T. ten Hacken, Irene H. Heijink
Publikováno v: Cells
Volume 10
Issue 11
Cells, 10(11):2860. MDPI AG
Cells, Vol 10, Iss 2860, p 2860 (2021)
COPD is characterized by irreversible lung tissue damage. We hypothesized that lung-derived mesenchymal stromal cells (LMSCs) reduce alveolar epithelial damage via paracrine processes, and may thus be suitable for cell-based strategies in COPD. We ai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb2b21d393440b2a43f058165f183036
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7
Novel Type 2-high gene clusters associated with corticosteroid sensitivity in COPD
Autor: Chih-Hsi Scott Kuo, W. Timens, Marissa Wisman, P. J. Sterk, van den Berge M, Martijn C. Nawijn, K.F. Chung, Pieter S. Hiemstra, Anthony Rowe, Alen Faiz, Yike Guo, Ratko Djukanovic, Stelios Pavlidis, Maarten P. van den Berg, I.M. Adcock
RationaleSevere asthma and COPD share common pathophysiologic traits such as relative corticosteroid insensitivity. We recently published three transcriptome-associated clusters (TACs) using hierarchical analysis of the sputum transcriptome in asthma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8a54f618b257ac3486b083cfa8aa97
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9
Late Breaking Abstract - Functional investigation of the corticosteroid resistance candidate FKBP5 using a CRISPR-Cas9 knockout model
Autor: Gerard H. Koppelman, Maarten van den Berge, Pieter S. Hiemstra, Marissa Wisman, Stephanie A. Christenson, Prescott G. Woodruff, Wim Timens, Alen Faiz, Irene H. Heijink
Publikováno v: European Respiratory Journal, 50. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Introduction: Corticosteroids are known for their anti-inflammatory effects in asthma and COPD. Severe asthma and COPD share common pathophysiologic traits such as airflow obstruction and corticosteroid insensitivity. Aim: To investigate genes upregu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146a9379187cb6d9c9e8b3091482412f
https://doi.org/10.1183/1393003.congress-2017.PA372
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