Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marissa K. Oram"'
Autor:
Ryan M. Baxley, Wendy Leung, Megan M. Schmit, Jacob Peter Matson, Lulu Yin, Marissa K. Oram, Liangjun Wang, John Taylor, Jack Hedberg, Colette B. Rogers, Adam J. Harvey, Debashree Basu, Jenny C. Taylor, Alistair T. Pagnamenta, Helene Dreau, Jude Craft, Elizabeth Ormondroyd, Hugh Watkins, Eric A. Hendrickson, Emily M. Mace, Jordan S. Orange, Hideki Aihara, Grant S. Stewart, Edward Blair, Jeanette Gowen Cook, Anja-Katrin Bielinsky
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Minichromosome maintenance protein 10 (MCM10) is critical for eukaryotic DNA replication. Here, by modelling MCM10 variants in human cell lines, the authors reveal a mechanism of MCM10-associated disease, finding that loss of MCM10 function constrain
Externí odkaz:
https://doaj.org/article/fcda6dd35e9949f888622bfe0a813011
Autor:
William E. Smith, Yen Yi Ho, Pramod Upadhyaya, Silvia Balbo, Donna Seabloom, Marissa K. Oram, Alessia Stornetta, Karin R. Vevang, Lisa A. Peterson, Stephen S. Hecht, M. Gerard O'Sullivan, Timothy S. Wiedmann, Andrew C. Floeder, Lin Zhang, Monica Flavin
Publikováno v:
Chemical Research in Toxicology. 34:723-732
Tobacco smoke is a complex mixture of chemicals, many of which are toxic and carcinogenic. Hazard assessments of tobacco smoke exposure have predominantly focused on either single chemical exposures or the more complex mixtures of tobacco smoke or it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3233272bd08a224c958268ddca7781a
https://doi.org/10.1021/acs.chemrestox.0c00350
https://doi.org/10.1021/acs.chemrestox.0c00350
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5391, p 5391 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 5391, p 5391 (2021)
Small ubiquitin-like modifier (SUMO)-targeted E3 ubiquitin ligases (STUbLs) are specialized enzymes that recognize SUMOylated proteins and attach ubiquitin to them. They therefore connect the cellular SUMOylation and ubiquitination circuits. STUbLs p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606ca7b617515ee0ec69f17168db4a2d
https://pubmed.ncbi.nlm.nih.gov/34065507
https://pubmed.ncbi.nlm.nih.gov/34065507
Autor:
Adam J. Harvey, Lulu Yin, Jacob Peter Matson, Jack Hedberg, Debashree Basu, John Taylor, Megan Schmit, Liangjun Wang, Jenny C. Taylor, Elizabeth Ormondroyd, Jordan S. Orange, Hideki Aihara, Edward Blair, Colette B. Rogers, Eric A. Hendrickson, Jeanette Gowen Cook, Ryan M. Baxley, Emily M. Mace, Alistair T. Pagnamenta, Anja Katrin Bielinsky, Wendy Leung, Hugh Watkins, Helene Dreau, Jude Craft, Marissa K. Oram, Grant S. Stewart
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Minichromosome maintenance protein 10 (MCM10) is essential for eukaryotic DNA replication. Here, we describe compound heterozygous MCM10 variants in patients with distinctive, but overlapping, clinical phenotypes: natural killer (NK) cell deficiency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c892fb3cd5e6fd2562c7cef29c0b5672
https://doi.org/10.1038/s41467-021-21878-x
https://doi.org/10.1038/s41467-021-21878-x
Autor:
Elizabeth Ormondroyd, Hideki Aihara, Emily M. Mace, Anja Katrin Bielinsky, James Taylor, Judith Craft, Alistair T. Pagnamenta, Ryan M. Baxley, Ed Blair, Helene Dreau, Jacob Peter Matson, Wendy Leung, Debashree Basu, Jenny C. Taylor, Grant S. Stewart, Megan Schmit, Jack Hedberg, Hugh Watkins, Adam J. Harvey, Lynn Wang, Colette B. Rogers, Eric A. Hendrickson, Lulu Yin, Cook Jg, Marissa K. Oram, Jordan S. Orange
Minichromosome maintenance protein 10 (Mcm10) is essential for eukaryotic DNA replication. Here, we describe compound heterozygous MCM10 mutations in patients with distinctive but overlapping clinical phenotypes – natural killer (NK) cell deficienc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c950e29951ab73bbca61c278674d00
https://doi.org/10.1101/844498
https://doi.org/10.1101/844498
Autor:
John A. Cidlowski, Amy R. Dwyer, Carol A. Lange, Tarah M. Regan Anderson, Branden A. Smeester, Carlos Perez Kerkvliet, Marissa K. Oram, Tiffany N. Seagroves
Publikováno v:
Journal of the Endocrine Society
Triple negative breast cancer (TNBC) is the most metastatic and deadliest breast cancer (BC) subtype, accounting for 20-30% of all BCs. There is a critical need to identify molecular targets that could be exploited as new biomarkers of TNBC prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a052e3e0cb281d4a6d8f83135df45
https://doi.org/10.1210/js.2019-sun-008
https://doi.org/10.1210/js.2019-sun-008
Autor:
Alessia Stornetta, Ingrid Cornax, Alexandru Flaviu Tăbăran, Timothy S. Wiedmann, Lisa A. Peterson, Donna Seabloom, Pramod Upadhyaya, Silvia Balbo, Lin Zhang, Marissa K. Oram, Stephen S. Hecht, M. Gerard O'Sullivan, Karin R. Vevang, William E. Smith, Monica Flavin
Publikováno v:
Cancer Prevention Research. 13:A19-A19
Tobacco is a complex chemical mixture, containing many toxicants and carcinogens. Most rodent risk assessment studies have focused on single chemicals or the complicated mixtures of tobacco smoke or its fractions. There are few studies evaluating how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f48d3a33bf923ba2addf2b3a5c19490
https://doi.org/10.1158/1940-6215.envcaprev19-a19
https://doi.org/10.1158/1940-6215.envcaprev19-a19