Výsledky vyhledávání - "Marissa DaSilva"

Fibroblast Response to Lanthanoid Metal Ion Stimulation: Potential Contribution to Fibrotic Tissue Injury

Autor: Muhammad Aslam, Patricia Perone, William Jenkins, Marissa DaSilva, Narasimharao Bhagavathula, James Varani, Kyle M. Walker, Michael K. Dame

Publikováno v: Biological Trace Element Research. 144:621-635

The purpose of this study was to compare each of the 14 naturally occurring lanthanoid metal ions for ability to stimulate pro-fibrotic responses in human dermal fibroblasts. When fibroblasts were exposed to individual lanthanoids over the concentrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a97334cb159f63da041e9b6bba4534b
https://doi.org/10.1007/s12011-011-9041-x

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Human colon tissue in organ culture: preservation of normal and neoplastic characteristics

Autor: Narasimharao Bhagavathula, Tejaswi Paruchuri, Marissa DaSilva, Michael K. Dame, Cohra C. Mankey, Muhammad Aslam, James Varani

Publikováno v: In Vitro Cellular & Developmental Biology - Animal. 46:114-122

Normal and neoplastic human colon tissue obtained at surgery was used to establish conditions for organ culture. Optimal conditions included an atmosphere of 5% CO2 and 95% O2; tissue partially submerged with mucosa at the gas interface; and serum-fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f1285b66ade73a5e870a388e18c7a4
https://doi.org/10.1007/s11626-009-9247-9

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A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin

Autor: Narasimharao Bhagavathula, Kent J. Johnson, Shannon D. McClintock, Marissa DaSilva, James Varani, Muhammad Aslam, Roscoe L. Warner, Adam G. Barron

Publikováno v: Wound Repair and Regeneration. 17:360-366

Hairless rats were topically treated with a combination of 10% curcumin and 3% ginger extract (or with each agent alone) for a 21-day period. Following this, the rats were treated topically with Temovate (corticosteroid) for an additional 15 days. At

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdcbb979e8de09e628fada9c6730bdbd
https://doi.org/10.1111/j.1524-475x.2009.00483.x

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Fibroblast Response to Gadolinium: Role for Platelet-Derived Growth Factor Receptor

Autor: Muhammad Aslam, Michael K. Dame, Marissa DaSilva, William Jenkins, Narasimharao Bhagavathula, James Varani, Patricia Perone

The purpose of this study was to assess the effects of gadolinium (Gd3+), provided as gadolinium chloride, on fibroblast function.Human dermal fibroblasts in monolayer culture and intact skin in organ culture were exposed to the lanthanide metal (1-2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b629be02ab76025edc877f9f835d0da4
https://europepmc.org/articles/PMC3164279/

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Responses of human skin in organ culture and human skin fibroblasts to a gadolinium-based MRI contrast agent: comparison of skin from patients with end-stage renal disease and skin from healthy subjects

Autor: Suzanne E.G. Fligiel, Kent J. Johnson, Michael K. Dame, James Varani, Monica OʼBrien Deming, Marissa DaSilva, Richard D. Swartz

Publikováno v: Investigative radiology. 45(11)

Nephrogenic systemic fibrosis is a clinical syndrome occurring in a small subset of patients with end-stage renal disease (ESRD). Exposure to certain of the gadolinium-based contrast agents during magnetic resonance imaging appears to be a trigger. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64728b45e58f3e108734f8a1b93e31f9
https://pubmed.ncbi.nlm.nih.gov/20661146

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Collagenolytic activity is suppressed in organ-cultured human skin exposed to a gadolinium-based MRI contrast agent

Autor: Kent J. Johnson, Narasimharao Bhagavathula, Marissa DaSilva, Patricia Perone, James Varani, Richard D. Swartz, Michael K. Dame, Muhammad Aslam, Tejaswi Paruchuri, Stephanie L. Weber

Publikováno v: Investigative radiology. 45(1)

Human skin produces increased amounts of matrix metalloproteinase-1 (MMP-1) when exposed in organ culture to Omniscan, one of the gadolinium-based MRI contrast agents (GBCA). MMP-1, by virtue of its ability to degrade structural collagen, contributes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409ca46aa0962b6e3dae0bf837b278c1
https://pubmed.ncbi.nlm.nih.gov/19996758

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A mineral-rich extract from the red marine algae Lithothamnion calcareum preserves bone structure and function in female mice on a Western-style diet

Autor: Narasimharao Bhagavathula, Muhammad Aslam, Ronald F. Zernicke, James Varani, Marissa DaSilva, Tejaswi Paruchuri, Steven A. Goldstein, Jaclynn M. Kreider

Publikováno v: Calcified tissue international. 86(4)

The purpose of this study was to determine whether a mineral-rich extract derived from the red marine algae Lithothamnion calcareum could be used as a dietary supplement for prevention of bone mineral loss. Sixty C57BL/6 mice were divided into three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd59e07f1bf75e93f94f8b27f38bbe9
https://pubmed.ncbi.nlm.nih.gov/20180099

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Regulation of Collagen Turnover in Human Skin Fibroblasts Exposed to a Gadolinium-Based Contrast Agent

Autor: Gary J. Fisher, James Varani, Yiru Xu, Kent J. Johnson, Muhammad Aslam, Marissa DaSilva, Roscoe L. Warner, Richard D. Swartz, Narasimharao Bhagavathula, Michael K. Dame

Objective: Nephrogenic systemic fibrosis is a clinical syndrome linked with exposure in renal failure patients to gadolinium-based contrast agents (GBCAs) during magnetic resonance imaging. Recently, we demonstrated that GBCA exposure led to increase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9371d6a6e6ecb5eb3b7dba9ad63d84
https://europepmc.org/articles/PMC2859439/

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The Göttingen minipig for assessment of retinoid efficacy in the skin: comparison of results from topically treated animals with results from organ-cultured skin

Autor: Tejaswi Paruchuri, James Varani, Marissa DaSilva, Narasimharao Bhagavathula, William Ridder, Michael K. Dame

Publikováno v: In vitro cellulardevelopmental biology. Animal. 45(9)

Göttingen minipigs were treated topically for 6 d with a novel retinoid (MDI 301) at concentrations ranging from 0.3% to 30% in cream vehicle. Treatment of the minipigs did not adversely affect their health (hematological and necropsy parameters) or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843f8fcc305b7a8a45a7143c4274b5f7
https://pubmed.ncbi.nlm.nih.gov/19536603

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