Výsledky vyhledávání - "Marissa A. Duckett"

Akademický článek

Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae

Autor: Kevin C. Ma, Tatum D. Mortimer, Marissa A. Duckett, Allison L. Hicks, Nicole E. Wheeler, Leonor Sánchez-Busó, Yonatan H. Grad

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

The mechanisms underlying resistance of Neisseria gonorrhoeae to the antibiotic azithromycin are incompletely understood. Here, Ma et al. conduct a conditional genome-wide association study to identify new resistance mutations and experimentally conf

Externí odkaz: https://doaj.org/article/f01d8464f9184f78b8e150f301aabff4

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Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae

Autor: Leonor Sánchez-Busó, Tatum D. Mortimer, Kevin C. Ma, Marissa A. Duckett, Allison L. Hicks, Nicole E. Wheeler, Yonatan H. Grad

Publikováno v: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

The emergence of resistance to azithromycin complicates treatment of Neisseria gonorrhoeae, the etiologic agent of gonorrhea. Substantial azithromycin resistance remains unexplained after accounting for known resistance mutations. Bacterial genome-wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cad1c83e47e0da54cc6e894e863ada
http://europepmc.org/articles/PMC7584619

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Increased power from bacterial genome-wide association conditional on known effects identifies Neisseria gonorrhoeae macrolide resistance mutations in the 50S ribosomal protein L4

Autor: Leonor Sánchez-Busó, Yonatan H. Grad, Marissa A. Duckett, Allison L. Hicks, Tatum D. Mortimer, Nicole E. Wheeler, Kevin C. Ma

The emergence of resistance to azithromycin complicates treatment of N. gonorrhoeae, the etiologic agent of gonorrhea. Population genomic analyses of clinical isolates have demonstrated that some azithromycin resistance remains unexplained after acco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906632d527b9c99da1ce5d00dcd8d9b9
https://doi.org/10.1101/2020.03.24.006650

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