Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marisol Montolio"'
Autor:
Lidia Matias-Valiente, Cristina Sanchez-Fernandez, Lara Rodriguez-Outeiriño, Maria C. Ramos, Caridad Díaz, Gloria Crespo, Victor González-Menéndez, Olga Genilloud, Fernando Reyes, Marisol Montolio, Francisco Hernandez-Torres, Amelia Eva Aranega
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116056- (2024)
Duchenne muscular dystrophy (DMD) is a devastating degenerative disease of skeletal muscles caused by loss of dystrophin, a key protein that maintains muscle integrity, which leads to progressive muscle degeneration aggravated by chronic inflammation
Externí odkaz:
https://doaj.org/article/21c8acebe9544a4186d507eb2fc439d3
Autor:
Lara Rodriguez-Outeiriño, Francisco Hernandez-Torres, Felicitas Ramirez de Acuña, Alberto Rastrojo, Carlota Creus, Alejandra Carvajal, Luis Salmeron, Marisol Montolio, Patricia Soblechero-Martin, Virginia Arechavala-Gomeza, Diego Franco, Amelia Eva Aranega
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 769-786 (2022)
Satellite cells (SCs), muscle stem cells, display functional heterogeneity, and dramatic changes linked to their regenerative capabilities are associated with muscle-wasting diseases. SC behavior is related to endogenous expression of the myogenic tr
Externí odkaz:
https://doaj.org/article/e03b3b8ff3f848cdb79d4103a8b2c6f8
Autor:
Carolina Migliorelli, Meritxell Gómez-Martinez, Paula Subías-Beltrán, Mireia Claramunt-Molet, Sebastian Idelsohn-Zielonka, Eudald Mas-Hurtado, Felip Miralles, Marisol Montolio, Marina Roselló-Ruano, Julita Medina-Cantillo
Publikováno v:
Sensors, Vol 23, Iss 2, p 831 (2023)
(1) Background: Duchenne (DMD) is a rare neuromuscular disease that progressively weakens muscles, which severely impairs gait capacity. The Six Minute-Walk Test (6MWT), which is commonly used to evaluate and monitor the disease’s evolution, presen
Externí odkaz:
https://doaj.org/article/42383bd4a82e4a3194558b41e68dc925
Autor:
Suzan M Hammond, Annemieke Aartsma‐Rus, Sandra Alves, Sven E Borgos, Ronald A M Buijsen, Rob W J Collin, Giuseppina Covello, Michela A Denti, Lourdes R Desviat, Lucía Echevarría, Camilla Foged, Gisela Gaina, Alejandro Garanto, Aurelie T Goyenvalle, Magdalena Guzowska, Irina Holodnuka, David R Jones, Sabine Krause, Taavi Lehto, Marisol Montolio, Willeke Van Roon‐Mom, Virginia Arechavala‐Gomeza
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
Abstract Nucleic acid‐based therapeutics that regulate gene expression have been developed towards clinical use at a steady pace for several decades, but in recent years the field has been accelerating. To date, there are 11 marketed products based
Externí odkaz:
https://doaj.org/article/76e52486fd764de6bb07b4e5106b079a
Autor:
Anna Duarri, Miguel Lopez de Heredia, Xavier Capdevila-Nortes, Margreet C. Ridder, Marisol Montolio, Tania López-Hernández, Ilja Boor, Chun-Fu Lien, Tracy Hagemann, Albee Messing, Dariusz C. Gorecki, Gert C. Scheper, Albert Martínez, Virginia Nunes, Marjo S. van der Knaap, Raúl Estévez
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 1, Pp 228-238 (2011)
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy, in the majority of cases caused by mutations in the MLC1 gene. MRI from MLC patients shows diffuse cerebral white matter signal abnormality and swellin
Externí odkaz:
https://doaj.org/article/ab7e770a271145778d5dd3d5e8bc9908
Autor:
Marisol Montolio, Nicole A. Datson, Francesco Muntoni, Eric P. Hoffman, Judith C.T. van Deutekom, Pallavi Lonkar, Michael Binks, Jane Owens, Virginia Arechavala-Gomeza, Glenn E. Morris, V. Ashutosh Rao, Rahul Phadke, Hendrik Neubert, Annemieke Aartsma-Rus, Jennifer E. Morgan
Publikováno v:
Journal of Neuromuscular Diseases
Representatives of academia, patient organisations, industry and the United States Food and Drug Administration attended a workshop on dystrophin quantification methodology. The aims of the workshop were to provide an overview of methods used to quan
Autor:
Annemieke Aartsma-Rus, Marisol Montolio, Gisela Gaina, Camilla Foged, Suzan M. Hammond, Alejandro Garanto, David R. Jones, Lourdes R. Desviat, Giuseppina Covello, Sabine Krause, Magdalena Guzowska, Virginia Arechavala-Gomeza, Sven Even F. Borgos, Willeke M. C. van Roon-Mom, Taavi Lehto, Sandra Alves, Ronald A.M. Buijsen, Michela A. Denti, Aurélie Goyenvalle, Rob W.J. Collin, Irina Holodnuka, Lucia Echevarria
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2021, 13 (4), ⟨10.15252/emmm.202013243⟩
e13243
EMBO Molecular Medicine, 13
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Molecular Medicine, 13(4). WILEY
Hammond, S M, Aartsma-Rus, A, Alves, S, Borgos, S E, Buijsen, R A M, Collin, R W J, Covello, G, Denti, M A, Desviat, L R, Echevarría, L, Foged, C, Gaina, G, Garanto, A, Goyenvalle, A T, Guzowska, M, Holodnuka, I, Jones, D R, Krause, S, Lehto, T, Montolio, M, Van Roon-Mom, W & Arechavala-Gomeza, V 2021, ' Delivery of oligonucleotide-based therapeutics : challenges and opportunities ', EMBO Molecular Medicine, vol. 13, no. 4, e13243 . https://doi.org/10.15252/emmm.202013243
Biblos-e Archivo. Repositorio Institucional de la UAM
EMBO Molecular Medicine, 13, 4
EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2021, 13 (4), ⟨10.15252/emmm.202013243⟩
e13243
EMBO Molecular Medicine, 13
Digital.CSIC. Repositorio Institucional del CSIC
instname
EMBO Molecular Medicine, 13(4). WILEY
Hammond, S M, Aartsma-Rus, A, Alves, S, Borgos, S E, Buijsen, R A M, Collin, R W J, Covello, G, Denti, M A, Desviat, L R, Echevarría, L, Foged, C, Gaina, G, Garanto, A, Goyenvalle, A T, Guzowska, M, Holodnuka, I, Jones, D R, Krause, S, Lehto, T, Montolio, M, Van Roon-Mom, W & Arechavala-Gomeza, V 2021, ' Delivery of oligonucleotide-based therapeutics : challenges and opportunities ', EMBO Molecular Medicine, vol. 13, no. 4, e13243 . https://doi.org/10.15252/emmm.202013243
Biblos-e Archivo. Repositorio Institucional de la UAM
EMBO Molecular Medicine, 13, 4
Nucleic acid‐based therapeutics that regulate gene expression have been developed towards clinical use at a steady pace for several decades, but in recent years the field has been accelerating. To date, there are 11 marketed products based on antis
Autor:
Manuel Gómez, Cristina Belén García, Feliciano J. Ramos, Marisol Montolio, María Pilar Ribate, David Flores
Publikováno v:
The European journal of health economics : HEPAC : health economics in prevention and care. 21(7)
To establish the potential economic burden in caregivers to patients with DMD and the potential causative factors.Caregivers to patients with DMD were recruited through the DMD patients Register and questioned about several economic aspects using "ad
Autor:
Marta Alonso-Gardón, Marisol Montolio, Xavier Capdevila-Nortes, Virginia Nunes, Xabier Elorza-Vidal, Héctor Gaitán-Peñas, Anna Duarri, Oscar Teijido, Tania López-Hernández, Efren Xicoy-Espaulella, Carla Pérez-Rius, Tanit Arnedo, Manuel Palacín, Mercedes Armand-Ugón, Raúl Estévez, Alejandro Barrallo-Gimeno, Sònia Sirisi
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy characterized by dysfunction of the role of glial cells in controlling brain fluid and ion homeostasis. Patients affected by MLC present macrocephaly, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eb301a1550a96b0ac3b809f390ffa6
http://hdl.handle.net/2445/199002
http://hdl.handle.net/2445/199002
Publikováno v:
Journal of Medicinal Chemistry. 55:9838-9846
Aberrant activation of signaling pathways plays a pivotal role in central nervous system disorders, such as Alzheimer's disease (AD). Using a combination of virtual screening and experimental testing, novel small molecule inhibitors of tPA-mediated e