Glycocalyx-mediated Cell Adhesion and Migration

Autor: Peter Friedl, Dirk Lefeber, Stephan Kissler, Lorenz Rognoni, Bettina Weigelin, Marina Krause-Vortmeyer, Luisa Bracci, Mietske Wijers-Rouw, Veronika te te Boekhorst, Mariska te Lindert, Joost te Riet, Samuel Schmidt, Jack A.M. Fransen, Anthea J. Messent, Kay-Eberhard Gottschalk, Barbara Lelli, Martin J. Humphries

SummaryCell migration is a force-dependent adaptive process mediated by integrin-dependent adhesion as well as other yet poorly defined interactions to the extracellular matrix. Using enzymatic multi-targeted digestion of sugar moieties on the surfac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::184c55122f084abbd3a57ea925ae5ab7
https://doi.org/10.1101/2020.06.12.149096

Cell migration through three-dimensional confining pores: speed accelerations by deformation and recoil of the nucleus

Autor: Anotida Madzvamuse, Philipp Isermann, Jan Schepens, Mariska te Lindert, Chandrasekhar Venkataraman, Feng Wei Yang, Wiljan Hendriks, Joost te Riet, Ralph J. A. Maas, Marina Krause, Katarina Wolf, Jan Lammerding

Publikováno v: Philosophical Transactions-Royal Society. Biological Sciences, 374
Philosophical Transactions of the Royal Society B: Biological Sciences
Philosophical Transactions-Royal Society. Biological Sciences, 374, 1779

Directional cell migration in dense three-dimensional (3D) environments critically depends upon shape adaptation and is impeded depending on the size and rigidity of the nucleus. Accordingly, the nucleus is primarily understood as a physical obstacle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e87bb3c2f6c52b950a9394029ee4ca
http://hdl.handle.net/2066/206046

Deregulation of focal adhesion formation and cytoskeletal tension due to loss of A-type lamins

Autor: Kris Gevaert, Jonathan Vandenbussche, Danahe Mohammed, Tom Sieprath, Winnok H. De Vos, Sylvain Gabriele, Katarina Wolf, Tobias Corne, Mariska te Lindert

Publikováno v: Cell adhesion & migration
Cell Adhesion & Migration, 11, 447-463
Cell Adhesion & Migration, 11, 5-6, pp. 447-463

Contains fulltext : 182727.pdf (Publisher’s version ) (Open Access) The nuclear lamina mechanically integrates the nucleus with the cytoskeleton and extracellular environment and regulates gene expression. These functions are exerted through direct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8a08b04c820c0202630187cc211b1a
https://hdl.handle.net/10067/1387550151162165141

The interaction of PTP-BL PDZ domains with RIL: An enigmatic role for the RIL LIM domain

Autor: Lieke C. J. van den Berk, Wiljan Hendriks, Geerten W. Vuister, Mariska te Lindert, Marco van Ham, Tine Walma, Jan Aelen

Publikováno v: ResearcherID

PDZ domains are protein-protein interaction modules that are crucial for the assembly of structural and signaling complexes. PDZ domains specifically bind short carboxyl-terminal peptides and occasionally internal sequences that structurally resemble

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081e5f53fdb2056c7c3bb23d8d136bf8
https://doi.org/10.1007/s11033-005-1407-8

Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype

Autor: Helma Pluk, Marieke Willemse, Amy L. Smift, Ad J.C. de Groof, Mariska te Lindert, Frank Oerlemans, Mike Winer, Jack A.M. Fransen, Bé Wieringa, Michiel M. T. van Dommelen, Min Wu

Publikováno v: Molecular Cancer, Vol 8, Iss 1, p 54 (2009)
Molecular Cancer

BackgroundThe Warburg phenotype in cancer cells has been long recognized, but there is still limited insight in the consecutive metabolic alterations that characterize its establishment. We obtained better understanding of the coupling between metabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5290cd65849004bd1b4aa16e9f343ac
https://doi.org/10.1186/1476-4598-8-54