Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

Autor: Rogelio Hernández-Pando, Olivier Neyrolles, Geanncarlo Lugo-Villarino, José Antonio Enciso-Moreno, Céline Cougoule, Mariana Haydee García-Hernández, Monica Alejandra Valtierra-Alvarado, Marisela Rubio-Caceres, Julio Enrique Castañeda-Delgado, Carmen J. Serrano, Bruno Rivas-Santiago, Nallely Lopez-Lopez, Ana Gabriela Ramos Martinez

Publikováno v: Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz, Instituto Oswaldo Cruz, Ministério da Saúde, 2018, 113 (4), ⟨10.1590/0074-02760170326⟩
Memórias do Instituto Oswaldo Cruz, Volume: 113, Issue: 4, Article number: e170326, Published: 19 FEB 2018
Memórias do Instituto Oswaldo Cruz.
Memórias do Instituto Oswaldo Cruz., Instituto Oswaldo Cruz, Ministério da Saúde, 2018, 113 (4), ⟨10.1590/0074-02760170326⟩
Memórias do Instituto Oswaldo Cruz., Vol 113, Iss 4 (2018)

BACKGROUND Type 2 diabetes (T2D) is a risk factor for the development of tuberculosis (TB), although the associated mechanisms are not known. OBJECTIVES To study the association between T2D and the basal phenotype of macrophages, and their immune res

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https://hal.archives-ouvertes.fr/hal-02348497