Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Marisan Mejillano"'
Publikováno v:
Journal of Biological Chemistry. 275:27746-27752
Gelsolin is activated by Ca(2+) to sever actin filaments. Ca(2+) regulation is conferred on the N-terminal half by the C-terminal half. This paper seeks to understand how Ca(2+) regulates gelsolin by testing the "tail helix latch hypothesis," which i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d94808301de74fbe9a31327a7ab997b
https://doi.org/10.1074/jbc.m003732200
https://doi.org/10.1074/jbc.m003732200
Autor:
Leslie D. Burtnick, Helen L. Yin, Senyon Choe, Vincent Le, Robert Robinson, Marisan Mejillano
Publikováno v:
Science. 286:1939-1942
The actin-binding protein gelsolin is involved in remodeling the actin cytoskeleton during growth-factor signaling, apoptosis, cytokinesis, and cell movement. Calcium-activated gelsolin severs and caps actin filaments. The 3.4 angstrom x-ray structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a19a03ffa49c9c7e4a311fb7176ba42
https://doi.org/10.1126/science.286.5446.1939
https://doi.org/10.1126/science.286.5446.1939
Publikováno v:
Journal of molecular biology. 324(4)
Gelsolin participates in the reorganization of the actin cytoskeleton that is required during such phenomena as cell movement, cytokinesis, and apoptosis. It consists of six structurally similar domains, G1-G6, which are arranged at resting intracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a853a558cc343f1f1bed4d5320c7522
https://pubmed.ncbi.nlm.nih.gov/12460571
https://pubmed.ncbi.nlm.nih.gov/12460571
Publikováno v:
Biochemistry. 40(4)
Gelsolin, an actin and phosphoinositide binding protein, was photoaffinity labeled using a variety of benzophenone-containing phosphoinositide polyphosphate analogues. The N-terminal half and the C-terminal half of gelsolin showed synergy in the bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6a6bcb048de82327001a60c63849b4
https://pubmed.ncbi.nlm.nih.gov/11170411
https://pubmed.ncbi.nlm.nih.gov/11170411
Autor:
Xiaodong Wang, Hui Qiao Sun, Marisan Mejillano, Helen L. Yin, Andrew L. Rozelle, Masaya Yamamoto
Publikováno v:
The Journal of biological chemistry. 276(3)
Phosphoinositides such as phosphatidylinositol 3,4,5-trisphosphate and phosphatidylinositol 3,4-bisphosphate promote cell survival and protect against apoptosis by activating Akt/PKB, which phosphorylates components of the apoptotic machinery. We now
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2475f86fadb0d4b1d819630dc936b3d
https://pubmed.ncbi.nlm.nih.gov/11042212
https://pubmed.ncbi.nlm.nih.gov/11042212
Publikováno v:
The Journal of biological chemistry. 274(47)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8294eaddd15172d611cabe2830f7879
https://pubmed.ncbi.nlm.nih.gov/10559185
https://pubmed.ncbi.nlm.nih.gov/10559185