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pro vyhledávání: '"Marisa Wong, Medina"'
Autor:
Marisa Wong Medina, Feng Gao, Devesh Naidoo, Lawrence L Rudel, Ryan E Temel, Allison L McDaniel, Stephanie M Marshall, Ronald M Krauss
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19420 (2011)
Genes involved in cholesterol biosynthesis and uptake are transcriptionally regulated in response to cellular sterol content in a coordinated manner. A number of these genes, including 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) and LDL r
Externí odkaz:
https://doaj.org/article/af36ab043a404bcfbb0dd11a4616be38
Autor:
Dan M. Roden, Julie A. Johnson, Stephen E. Kimmel, Ronald M. Krauss, Marisa Wong Medina, Alan Shuldiner, Russell A. Wilke
Publikováno v:
Circulation research. 109(7)
Patients vary in their responses to drug therapy, and some of that variability is genetically determined. This review outlines general approaches used to identify genetic variation that influences drug response. Examples from specific therapeutic are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603e9b7e94a8be47cd586d43d1741f6c
https://pubmed.ncbi.nlm.nih.gov/21921273
https://pubmed.ncbi.nlm.nih.gov/21921273
Autor:
Marisa Wong, Medina
Publikováno v:
Discovery medicine. 9(49)
Statins are a class of cholesterol lowering drugs that inhibit 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR), the enzyme which catalyzes the rate limiting step of cholesterol biosynthesis. Although numerous trials have demonstrated statin e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eded5fb5bd5865c8c17bad87254e2c9f
https://pubmed.ncbi.nlm.nih.gov/20587337
https://pubmed.ncbi.nlm.nih.gov/20587337