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Autor:
Sonja Zweegman, Gert J. Ossenkoppele, Pauline A. Merle, A H Loonen, Marisa Westers, Pino J. Poddighe, Hans Wessels, Shama L. Bhola, Marielle J. Wondergem
Publikováno v:
Poddighe, P J, Wessels, H, Merle, P, Westers, T M, Bhola, S L, Loonen, A, Zweegman, S, Ossenkoppele, G J & Wondergem, M J 2014, ' Genomic amplification of MYC as double minutes in a patient with APL-like leukemia ', Molecular cytogenetics, vol. 7, 67 . https://doi.org/10.1186/s13039-014-0067-6
Molecular cytogenetics, 7:67. BioMed Central
Molecular Cytogenetics
Molecular cytogenetics, 7:67. BioMed Central
Molecular Cytogenetics
Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) characterized by a PML-RARA fusion due to a translocation t(15;17). Its sensitivity to treatment with all-trans retinoic acid (ATRA), which causes differentiat