Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Marisa S. Klein-Gitelman"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study investigates the prevalence of dyslipidemia and its association with disease activity in children with Juvenile Dermatomyositis (JDM). A retrospective chart review of 142 JDM patients who had fasting lipid profiles was conducted.
Externí odkaz:
https://doaj.org/article/d845f689a1964068aff779cfe5edb16d
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Juvenile Dermatomyositis (JDM) is a rare autoimmune disease characterized by skin and muscle inflammation. The loss of nail fold capillary end row loops (ERL) is evidence of small vessel involvement in JDM. This study aimed to exa
Externí odkaz:
https://doaj.org/article/c7acdad65fcb49b994bbb98c1899a0b7
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background We lack a reliable indicator of disease activity in Juvenile Dermatomyositis (JDM), a rare disease. The goal of this study is to identify the association of nailfold capillary End Row Loop (ERL) loss with disease damage in childre
Externí odkaz:
https://doaj.org/article/4b585883cc3243d48e7bdefe626cf7bf
Autor:
Amer Khojah, Lauren M. Pachman, Ameera Bukhari, Chi Trinh, Gabrielle Morgan, Surya Pandey, I. Caroline Le Poole, Marisa S. Klein-Gitelman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7126 (2024)
Juvenile Dermatomyositis (JDM) is the most common inflammatory myopathy in pediatrics. This study evaluates the role of Natural Killer (NK) cells in Juvenile Dermatomyositis (JDM) pathophysiology. The study included 133 untreated JDM children with an
Externí odkaz:
https://doaj.org/article/def0db7fa6364fde97d305ad9f9bd3d4
Autor:
Ameera Bukhari, Amer Khojah, Wilfredo Marin, Andrey Khramtsov, Galina Khramtsova, Christopher Costin, Gabrielle Morgan, Prathyaya Ramesh, Marisa S. Klein-Gitelman, I. Caroline Le Poole, Lauren M. Pachman
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10553 (2023)
Otoferlin mRNA expression is increased in JDM patients’ PBMCs and muscle compared to healthy controls. This study aims to evaluate the role of otoferlin in JDM disease pathophysiology and its association with disease activity in untreated children
Externí odkaz:
https://doaj.org/article/fee98d5fa15a414f9455ee8190f840ea
Autor:
Amer M. Khojah, Michael L. Miller, Marisa S. Klein-Gitelman, Megan L. Curran, Victoria Hans, Lauren M. Pachman, Ramsay L. Fuleihan
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 17, Iss 1, Pp 1-7 (2019)
Abstract Background Despite the increased use of rituximab in treating pediatric patients with autoimmune diseases in the last decade, there are limited data on rituximab safety in those subjects who have a developing immune system. The objective of
Externí odkaz:
https://doaj.org/article/a5c06d67af524dcc955000d6f0860a48
Autor:
Jessica L. Turnier, Ndate Fall, Sherry Thornton, David Witte, Michael R. Bennett, Simone Appenzeller, Marisa S. Klein-Gitelman, Alexei A. Grom, Hermine I. Brunner
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background Improved, noninvasive biomarkers are needed to accurately detect lupus nephritis (LN) activity. The purpose of this study was to evaluate five S100 proteins (S100A4, S100A6, S100A8/9, and S100A12) in both serum and urine as potent
Externí odkaz:
https://doaj.org/article/f30f67eed9284777beeaa2f31678ec99
Autor:
Jennifer Faerber, Andrea M. Knight, Zuleyha Cidav, Sarah Shapiro, Hannah Katcoff, Marisa S. Klein-Gitelman, David S. Mandell, Joyce C. Chang, Alaina M. Davis
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE. To examine glucocorticoid-sparing immunomodulatory medication use in youth with systemic lupus erythematosus (SLE) during their first year of care. METHODS. We conducted a retrospective cohort study using administrative claims for 2000 to
Autor:
Alaina M. Davis, Joyce C. Chang, David S. Mandell, Zuleyha Cidav, Andrea M. Knight, Marisa S. Klein-Gitelman
Publikováno v:
Arthritis Care & Research. 73:30-38
OBJECTIVE Youth with systemic lupus erythematosus (SLE) experience high rates of psychiatric comorbidities, which may affect medication adherence. We undertook this study to examine the association between psychiatric disorders and hydroxychloroquine
Autor:
Patricia Costa-Reis, Kelly Maurer, Michelle A Petri, Daniella Levy Erez, Xue Zhao, Walter Faig, Jon Burnham, Kathleen O'Neil, Marisa S Klein-Gitelman, Emily von Scheven, Laura Eve Schanberg, Kathleen E Sullivan
Publikováno v:
Lupus sciencemedicine. 9(1)
ObjectiveLupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury. An unmet need is a biomarke