Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Marisa Klopper"'
Autor:
Christian C. Otum, Emmanuel Rivière, Monique Barnard, Johannes Loubser, Monique J. Williams, Elizabeth M. Streicher, Annelies Van Rie, Robin M. Warren, Marisa Klopper
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Molecular detection of bedaquiline resistant tuberculosis is challenging as only a small proportion of mutations in candidate bedaquiline resistance genes have been statistically associated with phenotypic resistance. We introduced two mutat
Externí odkaz:
https://doaj.org/article/ae71f361f4b04dd4ba76f7495f679496
Autor:
Marisa Klopper, Tim Hermanus Heupink, Grant Hill-Cawthorne, Elizabeth Maria Streicher, Anzaan Dippenaar, Margaretha de Vos, Abdallah Musa Abdallah, Jason Limberis, Matthias Merker, Scott Burns, Stefan Niemann, Keertan Dheda, James Posey, Arnab Pain, Robin Mark Warren
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Atypical Beijing genotype Mycobacterium tuberculosis strains are widespread in South Africa and have acquired resistance to up to 13 drugs on multiple occasions. It is puzzling that these strains have retained fitness and transmis
Externí odkaz:
https://doaj.org/article/94b53d5408b144e69d8124dbfc6439ad
Autor:
Violet N Chihota, Antoinette Niehaus, Elizabeth M Streicher, Xia Wang, Samantha L Sampson, Peter Mason, Gunilla Källenius, Sayoki G Mfinanga, Marnomorney Pillay, Marisa Klopper, Webster Kasongo, Marcel A Behr, Nicolaas C Gey van Pittius, Paul D van Helden, David Couvin, Nalin Rastogi, Robin M Warren
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0200632 (2018)
OBJECTIVE:To investigate the distribution of Mycobacterium tuberculosis genotypes across Africa. METHODS:The SITVIT2 global repository and PUBMED were searched for spoligotype and published genotype data respectively, of M. tuberculosis from Africa.
Externí odkaz:
https://doaj.org/article/34c5093264e9418c983b4caa213bfdab
Autor:
Marisa Klopper, Robin Mark Warren, Cindy Hayes, Nicolaas Claudius Gey van Pittius, Elizabeth Maria Streicher, Borna Müller, Frederick Adriaan Sirgel, Mamisa Chabula-Nxiweni, Ebrahim Hoosain, Gerrit Coetzee, Paul David van Helden, Thomas Calldo Victor, André Phillip Trollip
Publikováno v:
Emerging Infectious Diseases, Vol 19, Iss 3, Pp 449-455 (2013)
Factors driving the increase in drug-resistant tuberculosis (TB) in the Eastern Cape Province, South Africa, are not understood. A convenience sample of 309 drug-susceptible and 342 multidrug-resistant (MDR) TB isolates, collected July 2008–July 20
Externí odkaz:
https://doaj.org/article/752f256ee912498094a22ee579b6b62a
Autor:
Frederick A Sirgel, Robin M Warren, Erik C Böttger, Marisa Klopper, Thomas C Victor, Paul D van Helden
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134190 (2015)
Externí odkaz:
https://doaj.org/article/c69fbd20c64f4b7b89cbd6ec533f0f36
Autor:
Frederick A Sirgel, Robin M Warren, Erik C Böttger, Marisa Klopper, Thomas C Victor, Paul D van Helden
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59414 (2013)
Genetically related Mycobacterium tuberculosis strains with alterations at codon 516 in the rpoB gene were observed amongst a substantial number of patients with drug resistant tuberculosis in the Eastern Cape Province (ECP) of South Africa. Mutation
Externí odkaz:
https://doaj.org/article/733f26b1d9164bffab43b5b2f421118d
Autor:
Borna Müller, Violet N Chihota, Manormoney Pillay, Marisa Klopper, Elizabeth M Streicher, Gerrit Coetzee, Andre Trollip, Cindy Hayes, Marlein E Bosman, Nicolaas C Gey van Pittius, Thomas C Victor, Sebastien Gagneux, Paul D van Helden, Robin M Warren
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70919 (2013)
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 incl
Externí odkaz:
https://doaj.org/article/6f539d71c1d946788e46497b52f06ab8
Autor:
Madhurananda Pahar, Marisa Klopper, Byron Reeve, Rob Warren, Grant Theron, Andreas Diacon, Thomas Niesler
Publikováno v:
2022 International Conference on Electrical, Computer and Energy Technologies (ICECET).
We present a deep learning based automatic cough classifier which can discriminate tuberculosis (TB) coughs from COVID-19 coughs and healthy coughs. Both TB and COVID-19 are respiratory diseases, contagious, have cough as a predominant symptom and cl
Publikováno v:
Computers in Biology and Medicine
We present an experimental investigation into the effectiveness of transfer learning and bottleneck feature extraction in detecting COVID-19 from audio recordings of cough, breath and speech. This type of screening is non-contact, does not require sp
Publikováno v:
International journal of tuberculosis and lung disease