Výsledky vyhledávání - "Marisa Harton"

Akademický článek

A pilot metabolomics study of tuberculosis immune reconstitution inflammatory syndrome

Autor: Carlos A.M. Silva, Barbara Graham, Kristofor Webb, Laura Vari Ashton, Marisa Harton, Annie F. Luetkemeyer, Samantha Bokatzian, Reem Almubarak, Sebabrata Mahapatra, Laura Hovind, Michelle A. Kendall, Diane Havlir, John T. Belisle, Mary Ann De Groote

Publikováno v: International Journal of Infectious Diseases, Vol 84, Iss , Pp 30-38 (2019)

Background: Diagnosis of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is challenging and new tools are needed for early diagnosis as well as to understand the biochemical events that underlie the pathology

Externí odkaz: https://doaj.org/article/79e18c5515ff412bb2f93e3b43ada4a9

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A pilot metabolomics study of tuberculosis immune reconstitution inflammatory syndrome

Autor: Sebabrata Mahapatra, Kristofor J. Webb, Reem Almubarak, Samantha Bokatzian, John T. Belisle, Diane V. Havlir, Anne F Luetkemeyer, Michelle A. Kendall, Laura Hovind, Barbara Graham, Carlos A.M. Silva, Marisa Harton, Laura V. Ashton, Mary Ann De Groote

Publikováno v: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
International Journal of Infectious Diseases, Vol 84, Iss, Pp 30-38 (2019)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e7ead286ac8c88d5f97888b1d7cd30
https://doi.org/10.1016/j.ijid.2019.04.015

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Identification and functional analysis of a galactosyltransferase capable of cholesterol glycolipid formation in the Lyme disease spirochete Borrelia burgdorferi

Autor: M. Nurul Islam, Maria Marques, Marisa Harton, Forgivemore Magunda, Petronella R. Hove, Mary Jackson, John T. Belisle

Publikováno v: PLoS ONE, Vol 16, Iss 6, p e0252214 (2021)
PLoS ONE

Borrelia burgdorferi (Bb), the etiological agent of Lyme disease, produces a series of simple glycolipids where diacylglycerol and cholesterol serve as the precursor. The cholesterol-based glycolipids, cholesteryl 6-O-acyl-β-D-galactopyranoside (ACG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450ff9e9518fa6fe417f2c0df82db0c1
https://doaj.org/article/26852f9c24c741649595ebc6826f8f82

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Immunoproteomic analysis of Borrelia miyamotoi for the identification of serodiagnostic antigens

Autor: Nicole E. Breuner, Maria Marques, John T. Belisle, Robert D. Gilmore, Gary P. Wormser, Emma K. Harris, Marisa Harton, Claudia R. Molins

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports

The tick-borne spirochete, Borrelia miyamotoi, is an emerging pathogen of public health significance. Current B. miyamotoi serodiagnostic testing depends on reactivity against GlpQ which is not highly sensitive on acute phase serum samples. Additiona

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b707439f842219960a2de01d3c39fbc
https://doi.org/10.1038/s41598-019-53248-5

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Francisella tularensis LVS Surface and Membrane Proteins as Targets of Effective Post-Exposure Immunization for Tularemia

Autor: Catharine M. Bosio, Jeffrey C. Chandler, Claudia R. Molins, Marisa Harton, Darragh G. Heaslip, Rebecca Anderson, Marjorie D. Sutherland, John T. Belisle

Publikováno v: Journal of Proteome Research

Francisella tularensis causes disease (tularemia) in a large number of mammals, including man. We previously demonstrated enhanced efficacy of conventional antibiotic therapy for tularemia by postexposure passive transfer of immune sera developed aga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fa1f0f634ce6cebfae2d74e657545d
https://doi.org/10.1021/pr500628k

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Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis

Autor: Edward D. Chan, Marisa Harton, Gopinath S. Palanisamy, Marcela Henao Tamayo, Diane J. Ordway, Megan L. Caraway, Crystal A. Shanley, Ian M. Orme, Randall J. Basaraba, Shaobin Shang

Publikováno v: Tuberculosis. 91:378-385

There is increasing evidence that clinical isolates of Mycobacterium tuberculosis that belong to the W-Beijing genotype of newly emerging strains are often of very high virulence when tested in small animal models, including the mouse and guinea pig.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef4334183e4b8e887fe99e749ad7b41
https://doi.org/10.1016/j.tube.2011.06.001

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Immune Response toMycobacterium tuberculosisand Identification of Molecular Markers of Disease

Autor: Marcela Henao-Tamayo, Mercedes Gonzalez-Juarrero, Diane J. Ordway, Randall J. Basaraba, Richard A. Slayden, William H. Hanneman, Marisa Harton, Luke C. Kingry, Ian M. Orme

Publikováno v: American Journal of Respiratory Cell and Molecular Biology. 40:398-409

The complex molecular events that occur within the host during the establishment of a Mycobacterium tuberculosis infection are poorly defined, thus preventing identification of predictive markers of disease progression and state. To identify such mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e87fae538958ada13b45cbda1bffc6
https://doi.org/10.1165/rcmb.2008-0248oc

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XCL1 (lymphotactin) chemokine produced by activated CD8 T cells during the chronic stage of infection withMycobacterium tuberculosisnegatively affects production of IFN-γ by CD4 T cells and participates in granuloma stability

Autor: Marcela Henao-Tamayo, Mercedes Gonzalez Juarrero, Ian M. Orme, Joaquin Sanchez-Campillo, John S. Spencer, Marisa Harton, David M. Higgins, Diane J. Ordway

Publikováno v: Journal of Leukocyte Biology. 82:1221-1229

CD8 T cell immune responses are known not to be essential during the initial stages of infection with Mycobacterium tuberculosis (Mtb), but their presence becomes important as the chronic infection ensues. The basis of this is still not clear. In pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7437e7bea5d7ea2d06093586d1ca945d
https://doi.org/10.1189/jlb.0607426

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The Hypervirulent Mycobacterium tuberculosis Strain HN878 Induces a Potent TH1 Response followed by Rapid Down-Regulation

Autor: Diane J. Ordway, Ian M. Orme, Marcela Henao-Tamayo, Randall J. Basaraba, Marisa Harton, Crystal A. Shanley, JoLynn Troudt, Gopinath S. Palanisamy

Publikováno v: ResearcherID

The HN878 strain of Mycobacterium tuberculosis is regarded as “hypervirulent” due to its rapid growth and reduced survival of infected mice when compared with other clinical isolates. This property has been ascribed due to an early increase in ty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd84482897262bfbeea131b084d809e
https://doi.org/10.4049/jimmunol.179.1.522

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Interleukin-10 production by lung macrophages in CBA xid mutant mice infected with Mycobacterium tuberculosis

Autor: Mercedes Gonzalez Juarrero, Ana Paula Junqueira-Kipnis, Marisa Harton, Randall J. Basaraba, Marcela Henao Tamayo, André Kipnis, Ian M. Orme

Publikováno v: Immunology. 115:246-252

Summary Mice on the CBA inbred strain background expressing the well characterized mutation designated xid in the cytoplasmic signalling enzyme Bruton’s protein kinase have been previously noted to illustrate shifts in T helper type 1 (Th1)/Th2 imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100434b25e89c9d69f7e2b1f4c8de9f0
https://doi.org/10.1111/j.1365-2567.2005.02136.x

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