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of 9
pro vyhledávání: '"Marisa Egan"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Enterohemorrhagic and enteropathogenic Escherichia coli are gastrointestinal pathogens that disrupt the intestinal microvilli to form attaching and effacing (A/E) lesions on infected cells and cause diarrhea. This pathomorphological trait is encoded
Externí odkaz:
https://doaj.org/article/c584682067bb43bfacbf0c01e17b4616
Autor:
Marisa Egan, Hui Wang, Annie I. Chen, Biao Kan, Jun Zhu, Ming Liu, Guijuan Hao, Xiaoman Yang, Mark Goulian, Haijian Zhou
Publikováno v:
Antimicrob Agents Chemother
Colistin is a drug of last resort for the treatment of many multidrug-resistant Gram-negative bacteria, including carbapenem-resistant Klebsiella pneumoniae (CRKP). However, bacteria readily acquire resistance to this antibiotic via lipopolysaccharid
Autor:
Mary Marino, Brian Critelli, Shantanu Bhatt, Chirag Upreti, Marisa Egan, Daniel Kalman, Sean P. Cleary
Publikováno v:
Microbial pathogenesis. 135
The diarrheic bacterium Escherichia albertii is a recent addition to the attaching and effacing (A/E) morphotype of pathogens. A/E pathogens cause disease by tightly attaching to intestinal cells, destroying their actin-rich microvilli, and triggerin
Autor:
Shantanu, Bhatt, Marisa, Egan, Brian, Critelli, Andrew, Kouse, Daniel, Kalman, Chirag, Upreti
Publikováno v:
Infection and immunity. 87(1)
The diarrheic attaching and effacing (A/E) pathogen Escherichia albertii was first isolated from infants in Bangladesh in 1991, although the bacterium was initially classified as Hafnia alvei. Subsequent genetic and biochemical interrogation of these
Autor:
Filippa G. Bagnasco, Melinda Harrison, Garrett Finn, David Dunbar, Machika Kaku, Rahat M. Aziz, Rodney A. King, Marisa Egan, Nitish S. Chimalakonda, Hannah M. Kolev, Daniel R. Evans, Allen W. Karstens, Christopher M. McDaniel, Lee E. Hughes, Megan L. Archambault, Marie C. Pizzorno, Jennifer E. Menninger, Robert C. Benjamin, Emily M. Lehmann, Karen K. Klyczek, Jakob R. Yankauskas, Hannah McDonald, Amelia M. Schick, Josephine E. Minick, Deborah Jacobs-Sera, Jade Connor, Megan C. Hartwell, Kayla M. Robinson, Haley Broomell, Kaitlyn E. Wathen, Kelly C. Lynch, Julia Y. Lee-Soety, Victoria A. Rose, Emily L. Stowe, Vassie C. Ware, Daniel S. Thomas, Bobby L. Gaffney, Shawn C. London, Daniel A. Russell, Kathryn M. Hyduchak, Jonathan L. Weinstein, Yasmene M. Warrad, Christine Zhang, Zachary T. Vonberg, Sarah Ball, Lorianna Vanderveen, Christopher J. Blasi, Corrina Tender, Morgan P. Silva, Katelyn M. Pruett, Claire A. Rinehart, Trevor Cross, Allison R. Thompson, Jeremy W. Sieker, Carter N. Lantz, Carlos A. Guerrero Bustamante, Katherine Borst, Jessica A. Dahlke, William Casazza, Cassandra T. Ott, Sarah K. Pellerino, Kelly E. Garrigan, J. Alfred Bonilla, Zachary S. Brynell, Morgan E. Lamey, Aswathi E. Jacob, Kate Allen, Emma A. Sweet, Francis E. Mele, Sierra N. Miller, Dylan Chudoff, Ashley B. Bue, Julia Schlossman, Graham F. Hatfull, Margaret A. Kenna, Kevin Hong Chen, Conner B. Brown, Christopher R. Fratus, Quynh D. Vo, Martha Nkangabwa, Mary A. Braun, Sydney O. Burke, Natalie Barrett, Bryan C. Gibbon, Courtney T. Nabua, Catherine M. Mageeney, William J. Pinamont, Stephanie E. Simon, Porter T. Swartz, Milan Dolan, Rohan Varma, Temiloluwa O. Lawson, Ross T. Pirnie, Kevin J. Mathew, Caroline K. Napoli, Rebecca A. Garlena, Jessica E. Medrano, Bethany M. Deaton, Welkin H. Pope, Chrystal Thomas, Michael A. Goedde, Amal Farooq, Gabbi Rickstrew, Hannah L. Vaught, A. Javier Lopez, Noah A. Stueven, Amanda L. Kobokovich, Tamarah L. Adair, Elizabeth A. Oates, Jacqueline F. Wyper, Elizabeth Kriese, Victoria M. Schneider, Susheel K. Khetarpal, Emily L. Heckman, Abby K. Fahnestock, Emilee J. Plautz, Travis N. Mavrich, Amanda K. Staples, Jonathan S. Lapin, Danielle M. DeNigris, Katrina Terry, In Young Lee, Sai A. Konde, Chloe A. Sells, Jennifer Huang, Marissa M. Silvi, Tetyana Martynyuk, Katherine C. DeRuff, Isabelle L. Steed, Kyra N. Curtis, Sarah J. Degroote, Scott M. Lee, Patrick A. Rimple, C. Joel McManus, Abigail T. Sweetman, Julia A. Cautela, Patricia Afram
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180517 (2017)
PLoS ONE
PLoS ONE
The vast bacteriophage population harbors an immense reservoir of genetic information. Almost 2000 phage genomes have been sequenced from phages infecting hosts in the phylum Actinobacteria, and analysis of these genomes reveals substantial diversity
Autor:
Thomas Buerkert, Christian Xander, Sarah Muche, Shantanu Bhatt, Jasmine Ramirez, Jamie Palmer, Elisabeth Mason, Jihad El-Fenej, Marisa Egan, Valerie Jenkins, Elizabeth Storm
Publikováno v:
Pathogens and disease. 75(1)
Enteropathogenic Escherichia coli (EPEC) is a significant cause of infantile diarrhea and death in developing countries. The pathogenicity island locus of enterocyte effacement (LEE) is essential for EPEC to cause diarrhea. Besides EPEC, the LEE is a
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 6 (2016)
Enterohemorrhagic and enteropathogenic Escherichia coli are gastrointestinal pathogens that disrupt the intestinal microvilli to form attaching and effacing (A/E) lesions on infected cells and cause diarrhea. This pathomorphological trait is encoded
Publikováno v:
Gene & Translational Bioinformatics.
The causal link between a pathogen’s gene and virulence can be established by fulfilling Molecular Koch’s Postulates, which, in turn, requires the engineering of targeted mutations in the predicted gene of interest. Within the past decade, the pa
Publikováno v:
Biological Procedures
Background The ability to introduce site-specific mutations in bacterial pathogens is essential towards understanding their molecular mechanisms of pathogenicity. This has been greatly facilitated by the genetic engineering technique of recombineerin