Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Marisa Brini"'
Autor:
Giulia Dematteis, Laura Tapella, Claudio Casali, Maria Talmon, Elisa Tonelli, Simone Reano, Adele Ariotti, Emanuela Pessolano, Justyna Malecka, Gabriela Chrostek, Gabrielė Kulkovienė, Danielius Umbrasas, Carla Distasi, Mariagrazia Grilli, Graham Ladds, Nicoletta Filigheddu, Luigia Grazia Fresu, Katsuhiko Mikoshiba, Carlos Matute, Paula Ramos-Gonzalez, Aiste Jekabsone, Tito Calì, Marisa Brini, Marco Biggiogera, Fabio Cavaliere, Riccardo Miggiano, Armando A. Genazzani, Dmitry Lim
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract IP3 receptor (IP3R)-mediated Ca2+ transfer at the mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) drives mitochondrial Ca2+ uptake and oxidative metabolism and is linked to different pathologies, including Parkinson’s disease
Externí odkaz:
https://doaj.org/article/ae705db1dd34467e896aab04041a0d1f
Autor:
Flavia Giamogante, Lucia Barazzuol, Francesca Maiorca, Elena Poggio, Alessandra Esposito, Anna Masato, Gennaro Napolitano, Alessio Vagnoni, Tito Calì, Marisa Brini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Mitochondrial and lysosomal activities are crucial to maintain cellular homeostasis: optimal coordination is achieved at their membrane contact sites where distinct protein machineries regulate organelle network dynamics, ions and metabolite
Externí odkaz:
https://doaj.org/article/5f2baa85ecbe4b12a99f116659747b47
Autor:
Elena Poggio, Francesca Vallese, Andreas J. W. Hartel, Travis J. Morgenstern, Scott A. Kanner, Oliver Rauh, Flavia Giamogante, Lucia Barazzuol, Kenneth L. Shepard, Henry M. Colecraft, Oliver Biggs Clarke, Marisa Brini, Tito Calì
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-13 (2023)
Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous recovery to serious illness and death. On March 2020, a global COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/6f24462f2be0478e821b38710e7c6258
Autor:
Francesca Vallese, Lorenzo Maso, Flavia Giamogante, Elena Poggio, Lucia Barazzuol, Andrea Salmaso, Raffaele Lopreiato, Laura Cendron, Lorella Navazio, Ginevra Zanni, Yvonne Weber, Tatjana Kovacevic-Preradovic, Boris Keren, Alessandra Torraco, Rosalba Carrozzo, Francesco Peretto, Caterina Peggion, Stefania Ferro, Oriano Marin, Giuseppe Zanotti, Tito Calì, Marisa Brini, Ernesto Carafoli
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-14 (2022)
Abstract Calcium concentration must be finely tuned in all eukaryotic cells to ensure the correct performance of its signalling function. Neuronal activity is exquisitely dependent on the control of Ca2+ homeostasis: its alterations ultimately play a
Externí odkaz:
https://doaj.org/article/f8d8e2b2d085473b97ba00579a8eca6a
Autor:
Laura Tapella, Giulia Dematteis, Marianna Moro, Beatrice Pistolato, Elisa Tonelli, Virginia Vita Vanella, Daniele Giustina, Aleida La Forgia, Elena Restelli, Elettra Barberis, Tito Cali, Marisa Brini, Salvatore Villani, Erika Del Grosso, Mariagrazia Grilli, Marcello Manfredi, Marco Corazzari, Ambra A. Grolla, Armando A. Genazzani, Dmitry Lim
Publikováno v:
Cell Death and Disease, Vol 13, Iss 10, Pp 1-16 (2022)
Abstract Deregulation of protein synthesis and ER stress/unfolded protein response (ER stress/UPR) have been reported in astrocytes. However, the relationships between protein synthesis deregulation and ER stress/UPR, as well as their role in the alt
Externí odkaz:
https://doaj.org/article/1066a2fb20314a06a672b12873373bd4
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 240 (2024)
Neurodegenerative diseases (NDs) encompass an assorted array of disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, each characterised by distinct clinical manifestations and underlying pathological mech
Externí odkaz:
https://doaj.org/article/96e290fabeab4f8dba4a7d9fd8a5deb3
Publikováno v:
Contact, Vol 5 (2022)
To maintain cellular homeostasis and to coordinate the proper response to a specific stimulus, information must be integrated throughout the cell in a well-organized network, in which organelles are the crucial nodes and membrane contact sites are th
Externí odkaz:
https://doaj.org/article/45f92bada1804659baca440afadea96d
Autor:
Francesca Vallese, Cristina Catoni, Domenico Cieri, Lucia Barazzuol, Omar Ramirez, Valentina Calore, Massimo Bonora, Flavia Giamogante, Paolo Pinton, Marisa Brini, Tito Calì
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The authors have previously reported split-GFP-based contact site sensors (SPLICS) to document endoplasmic reticulum/mitochondria contact sites. Here they extend this work and develop a range of improved SPLICS sensors to detect single and multiple o
Externí odkaz:
https://doaj.org/article/605e86eacf834bb7bdf8a03fe68ceb5e
Publikováno v:
Cells, Vol 11, Iss 10, p 1643 (2022)
The study of organelle contact sites has received a great impulse due to increased interest in the understanding of their involvement in many disease conditions. Split-GFP-based contact sites (SPLICS) reporters emerged as essential tools to easily de
Externí odkaz:
https://doaj.org/article/658382a25dbf48b5a3cbbdb029c60dcd
Autor:
Ilaria Caputo, Brasilina Caroccia, Ilaria Frasson, Elena Poggio, Stefania Zamberlan, Margherita Morpurgo, Teresa M. Seccia, Tito Calì, Marisa Brini, Sara N. Richter, Gian Paolo Rossi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 5125 (2022)
Blockers of the renin-angiotensin system (RAS) have been reported to increase the angiotensin converting enzyme (ACE)2, the cellular receptor of SARS-CoV-2, and thus the risk and course of COVID-19. Therefore, we investigated if angiotensin (Ang) II
Externí odkaz:
https://doaj.org/article/e6c61b54e3534205a84eddd90ec744db