Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marisa A P, Baptista"'
Autor:
Marco R. Rink, Marisa A. P. Baptista, Felix J. Flomm, Thomas Hennig, Adam W. Whisnant, Natalia Wolf, Jürgen Seibel, Lars Dölken, Jens B. Bosse
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Fluorogenic aptamers are an alternative to established methodology for real-time imaging of RNA transport and dynamics. We developed Broccoli-aptamer concatemers ranging from 4 to 128 substrate-binding site repeats and characterized their behavior fu
Externí odkaz:
https://doaj.org/article/21840b55e9c4416483655d04ba35b5a6
Autor:
Mariana M. S. Oliveira, Roberta D’Aulerio, Tracer Yong, Minghui He, Marisa A. P. Baptista, Susanne Nylén, Lisa S. Westerberg
Publikováno v:
British Journal of Cancer. 128:982-991
Background Dendritic cell (DC) vaccines for cancer therapy offer the possibility to let the patient’s own immune system kill cancer cells. However, DC vaccines have shown less efficacy than expected due to failure to induce cancer cell killing and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95482702622bb473971d63d249fd7e6c
https://doi.org/10.1038/s41416-022-02135-4
https://doi.org/10.1038/s41416-022-02135-4
Autor:
Nikolai V. Kuznetsov, Bader Almuzzaini, Joanna S. Kritikou, Marisa A. P. Baptista, Mariana M. S. Oliveira, Marton Keszei, Scott B. Snapper, Piergiorgio Percipalle, Lisa S. Westerberg
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-18 (2017)
Abstract Background The Wiskott–Aldrich syndrome protein (WASp) family of actin-nucleating factors are present in the cytoplasm and in the nucleus. The role of nuclear WASp for T cell development remains incompletely defined. Methods We performed W
Externí odkaz:
https://doaj.org/article/0361830f057d4d0aa6483dff822ab402
Autor:
Marisa A. P. Baptista, Marton Keszei, Mariana Oliveira, Karen K. S. Sunahara, John Andersson, Carin I. M. Dahlberg, Austen J. Worth, Agne Liedén, I-Chun Kuo, Robert P. A. Wallin, Scott B. Snapper, Liv Eidsmo, Annika Scheynius, Mikael C. I. Karlsson, Gerben Bouma, Siobhan O. Burns, Mattias N. E. Forsell, Adrian J. Thrasher, Susanne Nylén, Lisa S. Westerberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Wiskott–Aldrich syndrome (WAS) is a severe X-linked primary immunodeficiency syndrome. Here, the authors show that loss of WAS gene in dendritic cells results in increased activity of Rac2, increase of phagosomal pH, and more efficient cross-presen
Externí odkaz:
https://doaj.org/article/b30cb5531b534a4c9f3e0c5bebf69da8
Autor:
Thomas Hennig, Marco Michalski, Andrzej J Rutkowski, Lara Djakovic, Adam W Whisnant, Marie-Sophie Friedl, Bhaskar Anand Jha, Marisa A P Baptista, Anne L'Hernault, Florian Erhard, Lars Dölken, Caroline C Friedel
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006954 (2018)
Lytic herpes simplex virus 1 (HSV-1) infection triggers disruption of transcription termination (DoTT) of most cellular genes, resulting in extensive intergenic transcription. Similarly, cellular stress responses lead to gene-specific transcription d
Externí odkaz:
https://doaj.org/article/0b734ce74d4b448b8f8c6a89158cb1cf
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
We sought to identify genes necessary to induce cytoskeletal change in B cells. Using gene expression microarray, we compared B cells stimulated with interleukin-4 (IL-4) and anti-CD40 antibodies that induce B cell spreading, cell motility, tight agg
Externí odkaz:
https://doaj.org/article/1031b4ffff70428283bc588be3caf0e8
Autor:
Karen K. S. Sunahara, Fernanda P. B. Nunes, Marisa A. P. Baptista, Carina Strell, Paulina Sannomiya, Lisa S. Westerberg, Joilson O. Martins
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 6, Pp 2017-2026 (2014)
Background/Aims: Diabetes mellitus (DM) is characterized by hyperglycemia, associated to a lack or inefficiency of the insulin to regulate glucose metabolism. DM is also marked by alterations in a diversity of cellular processes that need to be furth
Externí odkaz:
https://doaj.org/article/bbb356bb06064add8e86c09b7c9a4552
Autor:
Julien Record, David P. Lane, Minghui He, Wenxia Song, Jaime James, Scott B. Snapper, Carin I. M. Dahlberg, Chiara Geyer, Peter Vandenberghe, Paul Drescher, Sonia Lain, Marisa A. P. Baptista, Lisa S. Westerberg, Katrin Pütsep, Amlan Biswas, Hannah Wurzer, Meike Thiemann, Hanna Brauner, Marton Keszei, Laura Köcher, Joanna S. Kritikou
Publikováno v:
J Clin Invest
Congenital neutropenia is characterized by low absolute neutrophil numbers in blood, leading to recurrent bacterial infections, and patients often require life-long granulocyte CSF (G-CSF) support. X-linked neutropenia (XLN) is caused by gain-of-func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d309e21692f7c99b7c5346bff3ac4d2
https://lirias.kuleuven.be/handle/123456789/627139
https://lirias.kuleuven.be/handle/123456789/627139
Autor:
Stefano Volpi, Carin I. M. Dahlberg, Luigi D. Notarangelo, Jolan E. Walter, Scott B. Snapper, Magda-Liz Torres, Mikael C. I. Karlsson, Lisa S. Westerberg, Sven H. Petersen, Marisa A. P. Baptista, Emilie K. Grasset, Marton Keszei
Publikováno v:
Journal of Autoimmunity. 62:81-92
Humoral immunodeficiency caused by mutations in the Wiskott-Aldrich syndrome protein (WASp) is associated with failure to respond to common pathogens and high frequency of autoimmunity. Here we addressed the question how deficiency in WASp and the ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46ab66b1839923a5e3f68b8e2a40262
https://doi.org/10.1016/j.jaut.2015.06.003
https://doi.org/10.1016/j.jaut.2015.06.003
Autor:
Michel J. Massaad, Raif S. Geha, Carin I. M. Dahlberg, Eva Severinson, Natalija Gerasimcik, Lisa S. Westerberg, Marisa A. P. Baptista
Publikováno v:
The Journal of Immunology. 194:4750-4758
The Rho GTPase Cdc42 coordinates regulation of the actin and the microtubule cytoskeleton by binding and activating the Wiskott–Aldrich syndrome protein. We sought to define the role of intrinsic expression of Cdc42 by mature B cells in their activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883592f5fe3747c0f7c3808ab967c06a
https://doi.org/10.4049/jimmunol.1401634
https://doi.org/10.4049/jimmunol.1401634