Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marisa, Cressatti"'
Autor:
Marisa Cressatti, Hyman M. Schipper
Publikováno v:
NeuroSci, Vol 3, Iss 2, Pp 284-299 (2022)
α-Synuclein is a key driver of the pathogenesis of Parkinson disease (PD). Heme oxygenase-1 (HO-1), a stress protein that catalyzes the conversion of heme to biliverdin, carbon monoxide and free ferrous iron, is elevated in PD-affected neural tissue
Externí odkaz:
https://doaj.org/article/9a0ade33d33340b7aff6c9b643907b20
Autor:
Julia M Galindez, Lamin Juwara, Marisa Cressatti, Mervyn Gornitsky, Ana M Velly, Hyman M Schipper
Publikováno v:
Journal of Central Nervous System Disease, Vol 13 (2021)
Background: Parkinson disease (PD) is the second most common neurodegenerative disease, affecting 2% of the population over 65 years of age. PD diagnosis is based on clinical examination and can only be confirmed during autopsy. In 2018, we reported
Externí odkaz:
https://doaj.org/article/010d77be932d4ffcac229b233dc9fc0c
Autor:
Carmela Galindez, Marisa Cressatti, Adrienne Liberman, Wei Song, Ariana Z Turk, Adam Smart, Ayda Tavitian, Hyman M. Schipper
Publikováno v:
Antioxidants & Redox Signaling. 32:1259-1272
Aims: In this original research communication, we assess the impact of shifting the window of glial HMOX1 overexpression in mice from early-to-midlife to mid-to-late life, resulting in two disparate conditions modeling schizophrenia (SCZ) and Parkins
Autor:
Julia M Galindez, Ana M. Velly, Mervyn Gornistky, Hyman M. Schipper, Olivia Canie, Marisa Cressatti, Lamin Juwara, Sara Marier, Eva S. Nkurunziza
Publikováno v:
Movement Disorders. 35:468-477
Background Parkinson's disease (PD) is the most common movement disorder among adults, affecting 2% of the world population older than 65 years of age. No diagnostic biomarker for routine use in clinical settings currently exists. Dysregulation of mi
Autor:
Mervyn Gornitsky, Ana M. Velly, Marisa Cressatti, Hyman M. Schipper, Julia M Galindez, Lamin Juwara
Publikováno v:
Journal of Central Nervous System Disease, Vol 13 (2021)
Journal of Central Nervous System Disease
Journal of Central Nervous System Disease
Background: Parkinson disease (PD) is the second most common neurodegenerative disease, affecting 2% of the population over 65 years of age. PD diagnosis is based on clinical examination and can only be confirmed during autopsy. In 2018, we reported
Autor:
Julia M Galindez, Mervyn Gornitsky, Ana M. Velly, Hyman M. Schipper, Shaun Eintracht, Marisa Cressatti, Lamin Juwara, Natalie Orlovetskie, Adrienne Liberman
Publikováno v:
Journal of neurochemistryREFERENCES. 157(6)
Heme oxygenase-1 (HO-1), a highly inducible stress protein that degrades heme to biliverdin, carbon monoxide, and free ferrous iron, is increased in blood and other biofluids of subjects with various systemic and neurological disorders. HO-1 does not
Publikováno v:
Progress in Neurobiology. 172:40-70
Under stressful conditions, cellular heme catabolism to carbon monoxide, iron and biliverdin is mediated by the 32 kDa enzyme, heme oxygenase-1 (HO-1). A wide range of pro-oxidant and inflammatory stimuli act on diverse consensus sequences within the
Autor:
Vimal Kothari, Ana M. Velly, Wei Song, Mervyn Gornitsky, Hyman M. Schipper, Adrienne Liberman, Marisa Cressatti
Publikováno v:
Movement Disorders. 33:583-591
Background and hypothesis To date, there are no chemical analytes, including biochemical indices of oxidative stress, metabolites of α-synuclein protein, and differential protein expression patterns on proteomic profiling, for use in clinics as a di
Autor:
Wei Song, Marisa Cressatti, Ayda Tavitian, Adrienne Liberman, Carmela Galindez, Hyman M. Schipper
Publikováno v:
Free Radical Biology and Medicine. 110:162-175
Schizophrenia is a neuropsychiatric disorder that features neural oxidative stress and glutathione (GSH) deficits. Oxidative stress is augmented in brain tissue of GFAP.HMOX1 transgenic mice which exhibit schizophrenia-relevant characteristics. The w
Autor:
Ayda, Tavitian, Marisa, Cressatti, Wei, Song, Ariana Z, Turk, Carmela, Galindez, Adam, Smart, Adrienne, Liberman, Hyman M, Schipper
Publikováno v:
Antioxidantsredox signaling. 32(17)