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pro vyhledávání: '"Marion Weismann"'
Autor:
Mark Knapp, Marion Weismann, Xiaohua Xin, Zhang Yanchen, Ed Iwanowicz, Allan S. Wagman, Charles Voliva, Sabina Pecchi, Frazier Kelly, Matthew Burger, Hanne Merrit, Joelle Verhagen, Zhi-Jie Ni, Keith B. Pfister, Thomas Hendrickson, Bartulis Sarah, Simon Ng, Joshua Haznedar, Aaron Smith, Gordana Atallah
Publikováno v:
ACS medicinal chemistry letters. 2(1)
Phospoinositide-3-kinases (PI3K) are important oncology targets due to the deregulation of this signaling pathway in a wide variety of human cancers. A series of 2-morpholino, 4-substituted, 6-(3-hydroxyphenyl) pyrimidines have been reported as poten