Výsledky vyhledávání - "Marion Watson"

Akademický článek

The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to severe psoriatic arthritis: the 3-arm parallel group SPEED randomized controlled trial

Autor: Marion Watson, William Tillett, Deepak Jadon, M. Sofia Massa, Anne Francis, Nicola Gullick, Ines Rombach, Yvonne Sinomati, Laura Tucker, Laura C. Coates

Publikováno v: Therapeutic Advances in Musculoskeletal Disease, Vol 16 (2024)

Objectives: The aim of the Severe Psoriatic arthritis – Early intervEntion to control Disease trial is to compare outcomes in psoriatic arthritis (PsA) patients with poor prognostic factors treated with standard step-up conventional synthetic disea

Externí odkaz: https://doaj.org/article/b7a2d5ac25cd48628cb36bc010fad689

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Akademický článek

Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial

Autor: Ioana R. Marian, Megan Goff, Jennifer A. E. Williams, Malvika Gulati, Mae Chester-Jones, Anne Francis, Marion Watson, Tonia L. Vincent, Sue Woollacott, Charles Mackworth-Young, Victoria Glover, Dominic Furniss, Matthew Gardiner, Sarah E. Lamb, Katy Vincent, Vicki S. Barber, Joanna Black, Susan J. Dutton, Fiona E. Watt

Publikováno v: Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-14 (2021)

Abstract Background Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. Whilst the relationship between sex hormones and

Externí odkaz: https://doaj.org/article/814a33c795b04098be6e8c16fca98923

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Akademický článek

Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis—study protocol for the MONITOR-PsA study, a trials within cohorts study design

Autor: Ines Rombach, William Tillett, Deepak Jadon, Laura Tucker, Marion Watson, Anne Francis, Yvonne Sinomati, Lucy Eldridge, Melina Dritsaki, Susan J. Dutton, Hussein Al-Mossawi, Nicola Gullick, Ben Thompson, Laura C. Coates

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-14 (2021)

Abstract Background The Tight Control of psoriatic arthritis (TICOPA) trial confirmed improved clinical outcomes with a treat to target (T2T) strategy in psoriatic arthritis (PsA). This consisted of 4-weekly review and escalation of ‘step up’ the

Externí odkaz: https://doaj.org/article/2b7b494ab1954a9d8c6ad4ce0e851af0

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Akademický článek

Clinical effectiveness of symptomatic therapy compared with standard step-up care for the treatment of low-impact psoriatic oligoarthritis: the two-arm parallel group randomised POISE feasibility study

Autor: Ines Rombach, Laura Tucker, William Tillett, Deepak Jadon, Marion Watson, Anne Francis, Yvonne Sinomati, Susan J Dutton, Laura C Coates

Publikováno v: Therapeutic Advances in Musculoskeletal Disease, Vol 14 (2022)

Introduction: In psoriatic arthritis (PsA), treatment recommendations support first-line use of disease-modifying antirheumatic drugs (DMARDs). There are few treatment strategy trials, and no previous studies have investigated tailored treatment choi

Externí odkaz: https://doaj.org/article/07ecc6a02f3640e795491f1a591f6c99

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Hand Osteoarthritis: investigating Pain Effects of estrogen-containing therapy (HOPE-e): a protocol for a feasibility randomised placebo-controlled trial

Autor: Mae Chester-Jones, Matthew D Gardiner, Sue Woollacott, Charles Mackworth-Young, Katy Vincent, Dominic Furniss, Marion Watson, Victoria Glover, Malvika Gulati, Susan J Dutton, Anne Francis, Sarah E Lamb, Joanna Black, Fiona E. Watt, Ioana R Marian, Megan Goff, Jennifer A E Williams, Tonia L. Vincent, Vicki S Barber

Publikováno v: Pilot and Feasibility Studies
Pilot and Feasibility Studies, Vol 7, Iss 1, Pp 1-14 (2021)

Background Hand osteoarthritis (OA) is a common condition, causing pain, stiffness and reduced quality of life. Incidence is higher amongst women, particularly around the age of the menopause. Whilst the relationship between sex hormones and OA has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1422249e9e0087baaf8f4d437e0c122d
https://doi.org/10.1186/s40814-021-00869-1

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Autor: Yvonne Sinomati, Deepak R. Jadon, Ines Rombach, Melina Dritsaki, William Tillett, Lucy Eldridge, Nicola J. Gullick, Hussein Al-Mossawi, Ben Thompson, Laura C. Coates, Marion Watson, Laura J. Tucker, Susan J Dutton, Anne Francis

Publikováno v: Trials
Trials, Vol 22, Iss 1, Pp 1-14 (2021)

Background The Tight Control of psoriatic arthritis (TICOPA) trial confirmed improved clinical outcomes with a treat to target (T2T) strategy in psoriatic arthritis (PsA). This consisted of 4-weekly review and escalation of ‘step up’ therapy (sin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b191e413114a1d76c9ccb764f3f8e6

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Extremity CT and ultrasound in the assessment of ankle injuries: occult fractures and ligament injuries

Autor: Marion Watson, David J. Wilson, Stuart A. Bullock, Georgina Allen

Publikováno v: Br J Radiol

Objective: To assess the rates of fractures and ligament injuries in patients with an acute ankle injury and a normal radiographic examination, and to consider the most appropriate examination protocol. Methods: Patients with an acute ankle injury wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e49b08c6a0aee7bab8bc889a6073cf
https://pubmed.ncbi.nlm.nih.gov/31742428

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Predicting poor outcome from simple ankle injuries: a prospective cohort study

Autor: Georgina M Allen, David J. Wilson, Marion Watson, Stuart A. Bullock

Publikováno v: The British Journal of Radiology. 91:20170213

Sprained ankles are common and when there are no signs or evidence of a fracture, conventional management is conservative. At present, there are no clinical markers to identify those that may develop persisting instability and disability that would r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f1e295c950abd1420977afcbeef136
https://doi.org/10.1259/bjr.20170213

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Meta-Analysis of the Association of the Taq1A Polymorphism with the Risk of Alcohol Dependency: A HuGE Gene-Disease Association Review

Autor: Simon Gates, David Ball, David R. Foxcroft, Marion Watson, Lesley Smith

Publikováno v: American Journal of Epidemiology. 167:125-138

The human dopamine 2 receptor Taq1A allele has been implicated as a vulnerability factor for alcohol dependence in a number of studies and reviews. To determine whether this allele is associated with alcoholism, the authors conducted a Human Genome E

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8b5205b4d46cda932e8550ce80eaa8
https://doi.org/10.1093/aje/kwm281

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Changes in shoulder muscle size and activity following treatment for breast cancer

Autor: Reza Oskrochi, Simon Ostlere, Elaine Sugden, Marion Watson, Rosamund Weatherall, Ragavan Srinanaganathan, Delva Shamley

Publikováno v: Breast Cancer Research and Treatment. 106:19-27

Morbidity of the shoulder after breast cancer is a well-known phenomenon. MRI studies have shown muscle morbidity in cervical cancer and prostate cancer. In breast cancer clinical observations and patient reports include muscle morbidity in a number

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebb8f780c0123b2152bc48d755ca69d
https://doi.org/10.1007/s10549-006-9466-7

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