Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marion V. Guérin"'
Publikováno v:
Cancers, Vol 14, Iss 14, p 3546 (2022)
The essential roles endorsed by macrophages and monocytes are well established in response to infections, where they contribute to launching the differentiation of specific T-lymphocytes for long-term protection. This knowledge is the result of dynam
Externí odkaz:
https://doaj.org/article/60f79b06f3564c7a9f44a92e0d9c26f7
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
It is well established that tumor-associated macrophages (TAM) found in most advanced tumors have a pro-tumoral role. In this context, TAM limit the activity of tumor-infiltrating lymphocytes (TIL), and a number of mechanisms have been described incl
Externí odkaz:
https://doaj.org/article/30a5c11d07104f99aa26b824b76d60d3
Autor:
Julia M. Weiss, Marion V. Guérin, Fabienne Regnier, Gilles Renault, Isabelle Galy-Fauroux, Lene Vimeux, Vincent Feuillet, Elisa Peranzoni, Maxime Thoreau, Alain Trautmann, Nadège Bercovici
Publikováno v:
OncoImmunology, Vol 6, Iss 10 (2017)
Regressing tumors are usually associated with a large immune infiltrate, but the molecular and cellular interactions that govern a successful anti-tumor immunity remain elusive. Here, we have triggered type I Interferon (IFN) signaling in a breast tu
Externí odkaz:
https://doaj.org/article/4ac923f415d746199290f548e5b954c5
Publikováno v:
Cancers. 14(14)
The essential roles endorsed by macrophages and monocytes are well established in response to infections, where they contribute to launching the differentiation of specific T-lymphocytes for long-term protection. This knowledge is the result of dynam
Autor:
Fabienne Regnier, Alain Trautmann, Grégoire Altan-Bonnet, Lene Vimeux, Marion V. Guérin, Julia Miriam Weiss, Vincent Feuillet, Nadège Bercovici, Emmanuel Donnadieu
Publikováno v:
Live Talks.
Background Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce a strong production of IFNα/β and the rejection of transplanted primary tumors. However, the efficacy of such therapeutic
Autor:
Fabienne Régnier, Diane Damotte, Jean Lemoine, Hanane Ouakrim, Marco Alifano, Emmanuel Donnadieu, Jérôme Biton, Marion V. Guérin, Audrey Lupo, Elisa Peranzoni, Nadège Bercovici, Lene Vimeux, Sarah Barrin, Chahrazade Kantari-Mimoun, Vincent Feuillet
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (17), pp.E4041-E4050. ⟨10.1073/pnas.1720948115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (17), pp.E4041-E4050. ⟨10.1073/pnas.1720948115⟩
Significance Cancer immunotherapy is a promising therapeutic intervention. However, complete and durable responses are seen in only a fraction of cancer patients. A key factor that limits therapeutic success is the lack of T cells in tumor cell regio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048f24a9f2b8aedcc4744a33373d59ba
https://hal.sorbonne-universite.fr/hal-01791995
https://hal.sorbonne-universite.fr/hal-01791995
Autor:
Marion V. Guerin, Fabienne Regnier, Vincent Feuillet, Lene Vimeux, Julia M. Weiss, Georges Bismuth, Gregoire Altan-Bonnet, Thomas Guilbert, Maxime Thoreau, Veronica Finisguerra, Emmanuel Donnadieu, Alain Trautmann, Nadège Bercovici
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Interferons have been shown to mediate tumour rejection. Here, in a spontaneous mouse model of breast cancer, the authors show that this is disrupted owing to high levels of TGFβ produced in the tumour.
Externí odkaz:
https://doaj.org/article/4998cfedc6d240aeaec2f8249ea1a3ed