Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Marion Tschernutter"'
Autor:
Anastasios Georgiadis, Marion Tschernutter, James W B Bainbridge, Kamaljit S Balaggan, Freya Mowat, Emma L West, Peter M G Munro, Adrian J Thrasher, Karl Matter, Maria S Balda, Robin R Ali
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0295782 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0015730.].
Externí odkaz:
https://doaj.org/article/a61a5b69821d4c4198e2f27c773c2a28
Autor:
Patrick Weber, Martin Thonhofer, Summer Averill, Gideon J. Davies, Andres Gonzalez Santana, Philipp Müller, Seyed A. Nasseri, Wendy A. Offen, Bettina M. Pabst, Eduard Paschke, Michael Schalli, Ana Torvisco, Marion Tschernutter, Christina Tysoe, Werner Windischhofer, Stephen G. Withers, Andreas Wolfsgruber, Tanja M. Wrodnigg, Arnold E. Stütz
Publikováno v:
Molecules, Vol 25, Iss 17, p 4025 (2020)
Glycosidase inhibitors have shown great potential as pharmacological chaperones for lysosomal storage diseases. In light of this, a series of new cyclopentanoid β-galactosidase inhibitors were prepared and their inhibitory and pharmacological chaper
Externí odkaz:
https://doaj.org/article/25403e0b400e40b799edabad23624a55
Autor:
Patrick Weber, Seyed A. Nasseri, Bettina M. Pabst, Ana Torvisco, Philipp Müller, Eduard Paschke, Marion Tschernutter, Werner Windischhofer, Stephen G. Withers, Tanja M. Wrodnigg, Arnold E. Stütz
Publikováno v:
Molecules, Vol 23, Iss 3, p 708 (2018)
From 1,2;3,4-di-O-isopropylidene-d-galactopyranose, a preliminary series of highly functionalized amino(hydroxymethyl)cyclopentanes was easily available. These amine-containing basic carbasugars featuring the d-galacto configuration are potent inhibi
Externí odkaz:
https://doaj.org/article/a27bac4e4727409bbaf742aa4e0e9f59
Autor:
Anastasios Georgiadis, Marion Tschernutter, James W B Bainbridge, Kamaljit S Balaggan, Freya Mowat, Emma L West, Peter M G Munro, Adrian J Thrasher, Karl Matter, Maria S Balda, Robin R Ali
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15730 (2010)
Cell-cell adhesion regulates the development and function of epithelia by providing mechanical support and by guiding cell proliferation and differentiation. The tight junction (TJ) protein zonula occludens (ZO)-1 regulates cell proliferation and gen
Externí odkaz:
https://doaj.org/article/ed7db6a99f1a47a485feca3e3b103677
Autor:
Michael Schalli, Seyed A. Nasseri, Werner Windischhofer, Ana Torvisco, Christina Tysoe, Wendy A. Offen, Stephen G. Withers, Patrick Weber, Philipp Müller, Marion Tschernutter, Summer Averill, Eduard Paschke, Andreas Wolfsgruber, Martin Thonhofer, Bettina M. Pabst, Arnold E. Stütz, Tanja M. Wrodnigg, Gideon J. Davies, Andrés G. Santana
Publikováno v:
Molecules
Molecules, Vol 25, Iss 4025, p 4025 (2020)
Volume 25
Issue 17
Molecules, Vol 25, Iss 4025, p 4025 (2020)
Volume 25
Issue 17
Glycosidase inhibitors have shown great potential as pharmacological chaperones for lysosomal storage diseases. In light of this, a series of new cyclopentanoid &beta
galactosidase inhibitors were prepared and their inhibitory and pharmacologica
galactosidase inhibitors were prepared and their inhibitory and pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a21aebf7315b8edceb182918f2e34f2
https://eprints.whiterose.ac.uk/167565/1/molecules_25_04025_v3.pdf
https://eprints.whiterose.ac.uk/167565/1/molecules_25_04025_v3.pdf
Autor:
Werner Windischhofer, Patrick Weber, Christina Tysoe, Marion Tschernutter, Martin Thonhofer, Bettina M. Pabst, Arnold E. Stütz, Eduard Paschke, Stephen G. Withers, Michael Schalli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:3431-3435
N-Functionalized amino(hydroxymethyl)cyclopentanetriols are potent inhibitors of β-d-galactosidases and, for the first time, could be shown to act as pharmacological chaperones for GM1-gangliosidosis-associated lysosomal acid β-galactosidase thus r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed27a0aed1953c4da5db501097ba30ba
https://doi.org/10.1016/j.bmcl.2017.05.086
https://doi.org/10.1016/j.bmcl.2017.05.086
Autor:
René Lebl, Bettina M. Pabst, Marion Tschernutter, Stephen G. Withers, Arnold E. Stütz, Patrick Weber, Eduard Paschke, Michael Schalli, Werner Windischhofer, Martin Thonhofer, Christina Tysoe
Publikováno v:
Carbohydrate Research. 442:31-40
By Morita-Baylis-Hillman reaction of 2,3-O-isopropylidene-D-glyceraldehyde with α,β-unsaturated carbonyl as well as hetero analogous carbonyl compounds such as acrylonitrile, suitable precursors of isofagomine and of 4-epi-isofagomine are available
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7d7402ced2e510646f59daf22ad93c
https://doi.org/10.1016/j.carres.2017.03.003
https://doi.org/10.1016/j.carres.2017.03.003
Autor:
Christina Tysoe, Stephen G. Withers, Werner Windischhofer, Roland Fischer, Michael Schalli, Martin Thonhofer, Eduard Paschke, Bettina M. Pabst, Tanja Rappitsch, Marion Tschernutter, Arnold E. Stütz
Publikováno v:
Carbohydrate Research. :15-22
From 1,2;3,4-di-O-isopropylidene-α-D-galactopyranose, a series of highly functionalized (hydroxymethyl)cyclopentanes was easily available. In line with reports by Reymond and Jager on similar structures, these amine containing basic carbasugars are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998661ff92ab5acdf19688c29b09da0c
https://doi.org/10.1016/j.carres.2017.03.009
https://doi.org/10.1016/j.carres.2017.03.009
Autor:
Michael, Schalli, Patrick, Weber, Christina, Tysoe, Bettina M, Pabst, Martin, Thonhofer, Eduard, Paschke, Arnold E, Stütz, Marion, Tschernutter, Werner, Windischhofer, Stephen G, Withers
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(15)
N-Functionalized amino(hydroxymethyl)cyclopentanetriols are potent inhibitors of β-d-galactosidases and, for the first time, could be shown to act as pharmacological chaperones for G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ed4dbd3162f1f4fd92a5e58c9b4bc4d
https://pubmed.ncbi.nlm.nih.gov/28600215
https://pubmed.ncbi.nlm.nih.gov/28600215
N-Substituted 5-amino-1-hydroxymethyl-cyclopentanetriols: A new family of activity promotors for a G
Autor:
Michael, Schalli, Christina, Tysoe, Roland, Fischer, Bettina M, Pabst, Martin, Thonhofer, Eduard, Paschke, Tanja, Rappitsch, Arnold E, Stütz, Marion, Tschernutter, Werner, Windischhofer, Stephen G, Withers
Publikováno v:
Carbohydrate research.
From 1,2;3,4-di-O-isopropylidene-α-D-galactopyranose, a series of highly functionalized (hydroxymethyl)cyclopentanes was easily available. In line with reports by Reymond and Jäger on similar structures, these amine containing basic carbasugars are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::72cc1c169945566b0f0d9aff6b56c373
https://pubmed.ncbi.nlm.nih.gov/28319682
https://pubmed.ncbi.nlm.nih.gov/28319682