Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Marion T. Conn"'
Autor:
Marion T. Conn, George M. Rodgers
Publikováno v:
Blood. 75:895-901
Elevated blood levels of homocysteine are associated with atherosclerosis and thrombotic disease. We previously reported that treatment of cultured endothelial cells with homocysteine increased endogenous factor V activity by activation of the cofact
Autor:
Marion T. Conn, Jie Tang, Kyle Mortara, Anjali Katrekar, Joseph J. Buggy, Ashley M. Smith, Jiansheng Wu, Doug Jeffery, Jun Sampang, Lee Honigberg, James M. Clark, Steve R. Williams
Publikováno v:
The Journal of biological chemistry. 281(16)
Stimulation of mature T cells activates a downstream signaling cascade involving temporally and spatially regulated phosphorylation and dephosphorylation events mediated by protein-tyrosine kinases and phosphatases, respectively. PTPN22 (Lyp), a non-
Autor:
Marion T. Conn, Brian E. Schultz, Jie Tang, Shawn Misialek, Ram Tahilramani, Lance Wong, Jiansheng Wu
Publikováno v:
Biochemistry. 43(34)
Histone deacetylase (HDAC) enzymes modulate gene expression through the deacetylation of acetylated lysine residues on histone proteins. They operate in biological systems as part of multiprotein corepressor complexes. To understand the reactivity of
Autor:
Annette Lee, Randall K. Saiki, Veronica Garcia, Christopher I. Amos, Monica Chang, Franak Batliwalla, Michael F. Seldin, Kristin G. Ardlie, Lee Honigberg, Marion T. Conn, Peter K. Gregersen, Douglas A. Jeffery, Daniel L. Kastner, Steven J. Schrodi, Ann B. Begovich, Lindsey A. Criswell, Victoria E.H. Carlton, John J. Sninsky, Sheng Yung P Chang, Ashley M. Smith, Joseph J. Catanese, Anand P. Chokkalingam, Elaine F. Remmers, Jill M. Spoerke, Linda B. McAllister, Heather C. Alexander, Qiqing Huang, Diane U. Leong
Publikováno v:
The American Journal of Human Genetics. (2):330-337
Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting approximately 1% of the adult population worldwide, with an estimated heritability of 60%. To identify genes involved in RA susceptibility, we investigated the associ