Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marion Soto"'
Autor:
André Kleinridders, Heather A. Ferris, Michelle L. Reyzer, Michaela Rath, Marion Soto, M. Lisa Manier, Jeffrey Spraggins, Zhihong Yang, Robert C. Stanton, Richard M. Caprioli, C. Ronald Kahn
Publikováno v:
Molecular Metabolism, Vol 12, Iss , Pp 113-121 (2018)
Objective: Glucose is the major energy substrate of the brain and crucial for normal brain function. In diabetes, the brain is subject to episodes of hypo- and hyperglycemia resulting in acute outcomes ranging from confusion to seizures, while chroni
Externí odkaz:
https://doaj.org/article/e3b3bf9b3ec147769c0344d2c9e1cbb6
Autor:
Shiho Fujisaka, Julian Avila-Pacheco, Marion Soto, Aleksandar Kostic, Jonathan M. Dreyfuss, Hui Pan, Siegfried Ussar, Emrah Altindis, Ning Li, Lynn Bry, Clary B. Clish, C. Ronald Kahn
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 3072-3086 (2018)
Summary: Diet, genetics, and the gut microbiome are determinants of metabolic status, in part through production of metabolites by the gut microbiota. To understand the mechanisms linking these factors, we performed LC-MS-based metabolomic analysis o
Externí odkaz:
https://doaj.org/article/60ccf368e5734442a9a4679d88badbcc
Autor:
Wilfrid Mazier, Katy Le Corf, Ccori Martinez, Héloïse Tudela, Déborah Kissi, Camille Kropp, Chrislain Coubard, Marion Soto, Frédéric Elustondo, Georges Rawadi, Sandrine P. Claus
Publikováno v:
Cells, Vol 10, Iss 4, p 823 (2021)
Obesity is associated with gut microbiota dysbiosis, characterized by a high Firmicutes/Bacteroidetes ratio. Gut-dwelling bacteria of the Christensenellaceae family have been proposed to act as keystones of the human gut ecosystem and to prevent adip
Externí odkaz:
https://doaj.org/article/49d113ac22db489e817fc04cebdc3f1c
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6379-6384
Previous studies have shown that insulin and IGF-1 signaling in the brain, especially the hypothalamus, is important for regulation of systemic metabolism. Here, we develop mice in which we have specifically inactivated both insulin receptors (IRs) a
Autor:
Khyati Girdhar, Marion Soto, Qian Huang, Lucie Orliaguet, Carly Cederquist, Bharathi Sundaresh, Jiang Hu, Maximilian Figura, Amol Raisingani, Emanuel E. Canfora, Ercument Dirice, Shiho Fujisaka, Gijs H. Goossens, Ellen E. Blaak, Rohit N. Kulkarni, C. Ronald Kahn, Emrah Altindis
Publikováno v:
Diabetes
Diabetes, 71(5), 945-960. American Diabetes Association
Diabetes, 71(5), 945-960. American Diabetes Association
Growing evidence indicates an important link between gut microbiota, obesity, and metabolic syndrome. Alterations in exocrine pancreatic function are also widely present in patients with diabetes and obesity. To examine this interaction, C57BL/6J mic
Autor:
Héloïse Tudela, Georges Rawadi, Marion Soto, Frédéric Elustondo, Wilfrid Mazier, Sandrine P. Claus, Chrislain Coubard, Camille Kropp, Ccori Martinez, Katy Le Corf, Déborah Kissi
Publikováno v:
Cells, Vol 10, Iss 823, p 823 (2021)
Cells
Volume 10
Issue 4
Cells
Volume 10
Issue 4
Obesity is associated with gut microbiota dysbiosis, characterized by a high Firmicutes/Bacteroidetes ratio. Gut-dwelling bacteria of the Christensenellaceae family have been proposed to act as keystones of the human gut ecosystem and to prevent adip
Autor:
Kevin Bullock, C. Ronald Kahn, Shiho Fujisaka, Clémence Herzog, Clary B. Clish, Julian A. Pacheco, Marion Soto
Publikováno v:
Molecular Psychiatry
Obesity and diabetes in humans are associated with increased rates of anxiety and depression. To understand the role of the gut microbiome and brain insulin resistance in these disorders, we evaluated behaviors and insulin action in brain of mice wit
Autor:
Marion Soto, Michelle L. Reyzer, Michaela Rath, Richard M. Caprioli, Jeffrey M. Spraggins, M. Lisa Manier, André Kleinridders, Robert Stanton, Heather A. Ferris, C. Ronald Kahn, Zhihong Yang
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 12, Iss, Pp 113-121 (2018)
Molecular Metabolism, Vol 12, Iss, Pp 113-121 (2018)
Objective Glucose is the major energy substrate of the brain and crucial for normal brain function. In diabetes, the brain is subject to episodes of hypo- and hyperglycemia resulting in acute outcomes ranging from confusion to seizures, while chronic
Autor:
C. Ronald Kahn, Julian Avila-Pacheco, Hui Pan, Jonathan M. Dreyfuss, Marion Soto, Shiho Fujisaka, Lynn Bry, Siegfried Ussar, Ning Li, Aleksandar Kostic, Clary B. Clish, Emrah Altindis
Publikováno v:
Cell Reports, Vol 22, Iss 11, Pp 3072-3086 (2018)
Cell Rep. 22, 3072-3086 (2018)
Cell Rep. 22, 3072-3086 (2018)
Summary: Diet, genetics, and the gut microbiome are determinants of metabolic status, in part through production of metabolites by the gut microbiota. To understand the mechanisms linking these factors, we performed LC-MS-based metabolomic analysis o
Autor:
Marion Soto, Lucie Orliaguet, Michelle L. Reyzer, C. Ronald Kahn, Richard M. Caprioli, M. Lisa Manier
Publikováno v:
Proceedings of the National Academy of Sciences. 115:810-815
Mice subjected to cold or caloric deprivation can reduce body temperature and metabolic rate and enter a state of torpor. Here we show that administration of pyruvate, an energy-rich metabolic intermediate, can induce torpor in mice with diet-induced