Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marion Scharte"'
Autor:
Henning D. Stubbe, Martin Lettau, Daniel L. Traber, Fritz Daudel, Matthias Lange, Martin Westphal, Marion Scharte, Hans-Georg Bone, Hugo Van Aken
Publikováno v:
Shock. 26:615-619
Besides providing effective analgesia, thoracic epidural anesthesia (TEA) has been shown to decrease perioperative morbidity and mortality. Because of its vasodilatory properties in association with the sympathetic blockade, however, TEA may potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38eaa85d2afe567918f44e8946440af
https://doi.org/10.1097/01.shk.0000228799.25797.fb
https://doi.org/10.1097/01.shk.0000228799.25797.fb
Autor:
Mitchell P. Fink, Marion Scharte
Publikováno v:
Critical Care Medicine. 31:S651-S657
Reduction in red blood cell mass, as well as structural and functional alterations of erythrocytes, occurs in critical illness. This review discusses these changes in red blood cell physiology, emphasizing the pathogenesis of anemia in intensive care
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b6d537bb84d8ca393fa477b5b19224
https://doi.org/10.1097/01.ccm.0000098036.90796.ed
https://doi.org/10.1097/01.ccm.0000098036.90796.ed
Publikováno v:
Intensive Care Medicine. 29:989-994
The nuclear enzyme Poly(ADP-Ribose)-Polymerase (PARP) has been hypothesized as playing a major role in various forms of inflammation. PARP activation is induced by DNA strand breakage and can result in intracellular energy depletion and, ultimately,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236c5e2fd7044d4b968429fd09ee409e
https://doi.org/10.1007/s00134-003-1738-7
https://doi.org/10.1007/s00134-003-1738-7
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 284:G373-G384
Cellular adaptation to hypoxia depends, in part, on the transcription factor hypoxia-inducible factor-1 (HIF-1). Normoxic cells exposed to an inflammatory milieu often manifest phenotypic changes, such as increased glycolysis, that are reminiscent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa0742b13ae9e5b21a93d87c5af7899
https://doi.org/10.1152/ajpgi.00076.2002
https://doi.org/10.1152/ajpgi.00076.2002
Publikováno v:
European journal of public health. 23(3)
Background: Adverse effects of single parenthood on children’s health have been reported before. Socio-economic difficulties are discussed as mediating factors. As child health also depends on environmental conditions, we investigated the impact of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5a0595784315312ed4df25798104a9
https://pubmed.ncbi.nlm.nih.gov/22683774
https://pubmed.ncbi.nlm.nih.gov/22683774
Autor:
Kerstin Jurk, Beate E. Kehrel, Hugo Van Aken, Alexander Zarbock, Marion Scharte, Kai Singbartl
Publikováno v:
FEBS letters. 580(27)
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that mediates the adaptive response to hypoxia. Increasing evidence suggests a crucial role for HIF-1 in immune reactions. Here we investigated the effect of the Th2 type cytokines IL-4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928e0f0f8c3f36c3cb88583e711550d6
https://pubmed.ncbi.nlm.nih.gov/17097641
https://pubmed.ncbi.nlm.nih.gov/17097641
Autor:
Takashi Uchiyama, Mitchell P. Fink, Zakaria S. Tawadrous, Russell L. Delude, Xianonan Han, Marion Scharte
Publikováno v:
The Journal of surgical research. 135(2)
Background Cellular adaptation to hypoxia is mediated in part by the transcription factor hypoxia-inducible factor 1 (HIF-1). Accumulating data suggest that pro-inflammatory mediators can up-regulate HIF-1α protein expression and HIF-1 DNA-binding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174d05634c30f359ed4faf8e0d4419a0
https://pubmed.ncbi.nlm.nih.gov/16930621
https://pubmed.ncbi.nlm.nih.gov/16930621
Publikováno v:
European journal of anaesthesiology. 23(2)
The enzyme haeme oxygenase-1 is highly inducible by oxidative agents. Its product carbon monoxide is thought to exert anti-inflammatory properties. We recently showed, that critically ill patients produce higher amounts of carbon monoxide compared to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bdaebf874a9a01016b2be43d3969469
https://pubmed.ncbi.nlm.nih.gov/16426465
https://pubmed.ncbi.nlm.nih.gov/16426465
Publikováno v:
Critical care medicine. 29(9)
OBJECTIVE Hypotension, vasodilation, and vasoplegia are characteristic signs of septic shock. The vasoconstrictive response to catecholamines typically is reduced. A decreased vasopressive effect of catecholamines can be observed in the late phase of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7e5e522252d32e904cd5dc0d42cc22
https://pubmed.ncbi.nlm.nih.gov/11546979
https://pubmed.ncbi.nlm.nih.gov/11546979
Autor:
Jörg Meyer, Hideo A. Baba, Hans-Georg Bone, C. Schulzki, Marion Scharte, Hugo Van Aken, Christiane Goeters
Publikováno v:
The Journal of nutrition. 131(5)
The possible beneficial effect of supplemental glutamine (Gln) in critically ill patients has been suggested to be mediated by the induction of the cytoprotective heat shock proteins (HSP)32 and HSP72. There is evidence that HSP72 and HSP32 have oppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429d66b5f706140288b348e60aa506f6
https://pubmed.ncbi.nlm.nih.gov/11340095
https://pubmed.ncbi.nlm.nih.gov/11340095