Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marion S. Schmidt-Zachmann"'
Publikováno v:
Experimental cell research. 402(1)
As epigenetic regulators are frequently dysregulated in acute myeloid leukemia (AML) we determined expression levels of the JmjC-protein NO66 in AML cell lines and sub fractions of healthy human hematopoietic cells. NO66 is absent in the AML cell lin
Publikováno v:
Journal of Cell Science
Journal of Cell Science, Company of Biologists, 2007, 120, pp.1412-1422
Journal of Cell Science, Company of Biologists, 2007, 120, pp.1412-1422
Given the prominence and the biological importance of the nucleus it is remarkable how little is still known about structure-forming proteins in the nuclear interior. The karyoskeletal protein NO145 has been identified as a major constituent of a fil
Autor:
Haruhiko Koseki, Yoko Mizutani-Koseki, Toshihisa Komori, Kyoichi Isono, Marion S. Schmidt-Zachmann
Publikováno v:
Genes & Development. 19:536-541
Polycomb group (PcG) proteins are responsible for the stable repression of homeotic (Hox) genes by forming multimeric protein complexes. We show (1) physical interaction between components of the U2 small nuclear ribonucleoprotein particle (U2 snRNP)
Publikováno v:
European Journal of Cell Biology. 84:279-294
The nucleolus is the most prominent intranuclear structure of almost all protein-synthesizing cells. It compromises a well-defined functional compartmentalization and a high complexity of molecular constituents. Here, we report on the identification
Autor:
V.M.Haridasan Namboodiri, Ildikó V. Akey, Marion S. Schmidt-Zachmann, Christopher W. Akey, James F. Head
Publikováno v:
Structure. 12:2149-2160
Xenopus NO38 is an abundant nucleolar chaperone and a member of the nucleoplasmin (Np) family. Here, we report high-resolution crystal structures of the N-terminal domain of NO38, as a pentamer and a decamer. As expected, NO38 shares the Np family fo
Autor:
Jens Eilbracht, Hans Heid, Michaela Hergt, Martina Schnölzer, Marion S. Schmidt-Zachmann, Michaela Reichenzeller, Werner W. Franke, Michael Stöhr
Publikováno v:
Molecular Biology of the Cell. 15:1816-1832
It has recently become clear that the nucleolus, the most prominent nuclear subcompartment, harbors diverse functions beyond its classic role in ribosome biogenesis. To gain insight into nucleolar functions, we have purified amplified nucleoli from X
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3849-3854
SF3b 155 is an essential spliceosomal protein, highly conserved during evolution. It has been identified as a subunit of splicing factor SF3b, which, together with a second multimeric complex termed SF3a, interacts specifically with the 12S U2 snRNP
Publikováno v:
Journal of Cell Science. 110:1051-1062
Using a specific monoclonal antibody (mAb AND-1/23-5-14) we have identified, cDNA-cloned and characterized a novel DNA-binding protein of the clawed toad, Xenopus laevis, that is accumulated in the nucleoplasm of oocytes and various other cells. This
Autor:
Atsushi Yamamoto, Marion S. Schmidt-Zachmann, Armin Thalhammer, Ming Yang, Gail M. Preston, James S. O. McCullagh, Alexander Wolf, Chia Hua Ho, Phebee Liu-Yi, Adam P. Hardy, Zhihong Zhang, Peter J. Ratcliffe, Adam Zayer, Carol V. Robinson, Tianshu Feng, Benedikt M. Kessler, Nikita D. Loik, Mathew L. Coleman, Rok Sekirnik, Timothy D. W. Claridge, Muhammad Mukram Mohamed Mackeen, Refaat B. Hamed, Miao Jiang, Matthew E. Cockman, Rasheduzzaman Chowdhury, Christoph Loenarz, Christopher J. Schofield, David C. Trudgian, Nicolas Granatino, Wei Ge, Yuliya Gordiyenko, Lingzhi Gong
Publikováno v:
Nature chemical biology. 8(12)
The finding that oxygenase-catalyzed protein hydroxylation regulates animal transcription raises questions as to whether the translation machinery and prokaryotic proteins are analogously modified. Escherichia coli ycfD is a growth-regulating 2-oxogl
Publikováno v:
Journal of Cell Science. 108:257-263
Primary transcripts in eukaryotic cells undergo several processing steps within the nucleus, and resulting mature RNA molecules are selectively exported to the cytoplasm. Nucleo-cytoplasmic mRNA transport is an active process that likely involves RNA