Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marion Rubis"'
Autor:
Angélina Acier, Magali Godard, Fanny Gassiot, Pascal Finetti, Marion Rubis, Jonathan Nowak, François Bertucci, Juan L. Iovanna, Richard Tomasini, Pascaline Lécorché, Guillaume Jacquot, Michel Khrestchatisky, Jamal Temsamani, Cédric Malicet, Sophie Vasseur, Fabienne Guillaumond
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Acier et al. investigated a peptide cargo system, the Fc(A680)-VH4127, that targets PDAC through the LDLR cell-surface receptor. The Fc(A680)-VH4127 was found to specifically target spontaneous pancreatic tumors in KICmice, as well as metastatic panc
Externí odkaz:
https://doaj.org/article/5ab9785210c145ccb6dcb8b2d12b4fdb
Autor:
Marjorie Adjuto-Saccone, Philippe Soubeyran, Julie Garcia, Stéphane Audebert, Luc Camoin, Marion Rubis, Julie Roques, Bernard Binétruy, Juan Lucio Iovanna, Roselyne Tournaire
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-15 (2021)
Abstract Endothelial–mesenchymal transition (EndMT) is an important source of cancer-associated fibroblasts (CAFs), which facilitates tumour progression. PDAC is characterised by abundant CAFs and tumour necrosis factor-α (TNF-α). Here, we show t
Externí odkaz:
https://doaj.org/article/3aa8e654cca2441fad193adeb9b1e12e
Autor:
Yousra Mohamed Abd-El-Halim, Abdessamad El Kaoutari, Françoise Silvy, Marion Rubis, Martin Bigonnet, Julie Roques, Jérôme Cros, Rémy Nicolle, Juan Iovanna, Nelson Dusetti, Eric Mas
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103541- (2021)
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an important heterogeneity, reflected by different clinical outcomes and chemoresistance. During carcinogenesis, tumor cells display aberrant glycosylated structures, synthetized
Externí odkaz:
https://doaj.org/article/6bdc66b51d9a458a9e97509acbe65ac8
Autor:
Rémy Nicolle, Yuna Blum, Pauline Duconseil, Charles Vanbrugghe, Nicolas Brandone, Flora Poizat, Julie Roques, Martin Bigonnet, Odile Gayet, Marion Rubis, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Aurélien de Reyniès, Marc Giovannini, Philippe Grandval, Stephane Garcia, Cindy Canivet, Jérôme Cros, Barbara Bournet, Vincent Moutardier, Marine Gilabert, Juan Iovanna, Nelson Dusetti, Louis Buscail
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102858- (2020)
Background: A significant gap in pancreatic ductal adenocarcinoma (PDAC) patient's care is the lack of molecular parameters characterizing tumours and allowing a personalized treatment. Methods: Patient-derived xenografts (PDX) were obtained from 76
Externí odkaz:
https://doaj.org/article/8918a4bc9a304a27b1233f14ef9164aa
Autor:
Rémy Nicolle, Yuna Blum, Laetitia Marisa, Celine Loncle, Odile Gayet, Vincent Moutardier, Olivier Turrini, Marc Giovannini, Benjamin Bian, Martin Bigonnet, Marion Rubis, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Pauline Duconseil, Mohamed Gasmi, Mehdi Ouaissi, Aurélie Maignan, Gwen Lomberk, Jean-Marie Boher, Jacques Ewald, Erwan Bories, Jonathan Garnier, Anthony Goncalves, Flora Poizat, Jean-Luc Raoul, Veronique Secq, Stephane Garcia, Philippe Grandval, Marine Barraud-Blanc, Emmanuelle Norguet, Marine Gilabert, Jean-Robert Delpero, Julie Roques, Ezequiel Calvo, Fabienne Guillaumond, Sophie Vasseur, Raul Urrutia, Aurélien de Reyniès, Nelson Dusetti, Juan Iovanna
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2458-2470 (2017)
Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine stromal cells computationally. We obtained 29 pancreatic ductal adenocarcinoma (PDAC) xenog
Externí odkaz:
https://doaj.org/article/1cd281d48e1a47c3af7a5a5caffb63ca
Autor:
Orianne Olivares, Jared R. Mayers, Victoire Gouirand, Margaret E. Torrence, Tristan Gicquel, Laurence Borge, Sophie Lac, Julie Roques, Marie-Noëlle Lavaut, Patrice Berthezène, Marion Rubis, Veronique Secq, Stéphane Garcia, Vincent Moutardier, Dominique Lombardo, Juan Lucio Iovanna, Richard Tomasini, Fabienne Guillaumond, Matthew G. Vander Heiden, Sophie Vasseur
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Cancer cells adapt their metabolism to survive limited nutrient availability. Here, the authors show that in conditions of limited glucose or glutamine availability, pancreatic ductal adenocarcinoma cells can use collagen-derived proline to foster th
Externí odkaz:
https://doaj.org/article/6a73d2e74efe45e79489251d11428d7b
Autor:
Benjamin Bian, Martin Bigonnet, Odile Gayet, Celine Loncle, Aurélie Maignan, Marine Gilabert, Vincent Moutardier, Stephane Garcia, Olivier Turrini, Jean‐Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Mehdi Ouaissi, Veronique Secq, Flora Poizat, Rémy Nicolle, Yuna Blum, Laetitia Marisa, Marion Rubis, Jean‐Luc Raoul, James E Bradner, Jun Qi, Gwen Lomberk, Raul Urrutia, Andres Saul, Nelson Dusetti, Juan Iovanna
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 4, Pp 482-497 (2017)
Abstract c‐MYC controls more than 15% of genes responsible for proliferation, differentiation, and cellular metabolism in pancreatic as well as other cancers making this transcription factor a prime target for treating patients. The transcriptome o
Externí odkaz:
https://doaj.org/article/9515095c62b544a4b91a053e07db531f
A Transcriptomic-Based Tool to Predict Gemcitabine Sensitivity in Advanced Pancreatic Adenocarcinoma
Autor:
Nicolas Fraunhoffer, Brice Chanez, Carlos Teyssedou, Juan L. Iovanna, Emmanuel Mitry, Nelson J. Dusetti, Martin Bigonnet, Claire Bongrain, Emilie Lermite, Patrick Pessaux, Fabio Giannone, Marie-Pierre Chenard, Sophie Michalak, Rémy Nicolle, Marion Rubis, Flora Poizat, Marc Giovannini, Fabrice Caillol, Philippe Rochigneux
Publikováno v:
Gastroenterology.
research support, non-u.s. gov't letter 2023 Mar 2022 12 07 imported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5d2cc273f9ff88d707e57169874f58
https://pubmed.ncbi.nlm.nih.gov/36496056
https://pubmed.ncbi.nlm.nih.gov/36496056
Autor:
Victoire Gouirand, Tristan Gicquel, Evan C Lien, Emilie Jaune‐Pons, Quentin Da Costa, Pascal Finetti, Elodie Metay, Camille Duluc, Jared R Mayers, Stephane Audebert, Luc Camoin, Laurence Borge, Marion Rubis, Julie Leca, Jeremy Nigri, François Bertucci, Nelson Dusetti, Juan Lucio Iovanna, Richard Tomasini, Ghislain Bidaut, Fabienne Guillaumond, Matthew G Vander Heiden, Sophie Vasseur
Publikováno v:
EMBO Journal
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
The EMBO journal, vol 41, iss 9
EMBO J
EMBO Journal, 2022, ⟨10.15252/embj.2021110466⟩
The EMBO journal, vol 41, iss 9
EMBO J
Pancreatic ductal adenocarcinoma (PDA) tumor cells are deprived of oxygen and nutrients and therefore must adapt their metabolism to ensure proliferation. In some physiological states, cells rely on ketone bodies to satisfy their metabolic needs, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402d390310382a7d2b9d332eef585cf9
https://hal-amu.archives-ouvertes.fr/hal-03623502
https://hal-amu.archives-ouvertes.fr/hal-03623502
Autor:
Maria Rita Emma, Antonella Cusimano, Karen Blyth, Maurizio Soresi, Melchiorre Cervello, Angela Listi, Daniela Cabibi, Christopher L. Pin, Sergiu Coslet, Rossana Porcasi, Gianni Pantuso, Marion Rubis, Giuseppa Augello, Juan L. Iovanna, Maria Teresa Borrello, Lydia Giannitrapani, Giuseppe Montalto
Publikováno v:
Paediatrics Publications
The FASEB journal (Online) 35 (2021): e21395. doi:10.1096/fj.202002413RR
info:cnr-pdr/source/autori:Teresa Borrello M; Rita Emma M; Listi A; Rubis M; Coslet S; Augello G; Cusimano A; Cabibi D; Porcasi R; Giannitrapani L; Soresi M; Pantuso G; Blyth K; Montalto G; Pin C; Cervello M; Iovanna J;/titolo:NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response/doi:10.1096%2Ffj.202002413RR/rivista:The FASEB journal (Online)/anno:2021/pagina_da:e21395/pagina_a:/intervallo_pagine:e21395/volume:35
The FASEB journal (Online) 35 (2021): e21395. doi:10.1096/fj.202002413RR
info:cnr-pdr/source/autori:Teresa Borrello M; Rita Emma M; Listi A; Rubis M; Coslet S; Augello G; Cusimano A; Cabibi D; Porcasi R; Giannitrapani L; Soresi M; Pantuso G; Blyth K; Montalto G; Pin C; Cervello M; Iovanna J;/titolo:NUPR1 protects liver from lipotoxic injury by improving the endoplasmic reticulum stress response/doi:10.1096%2Ffj.202002413RR/rivista:The FASEB journal (Online)/anno:2021/pagina_da:e21395/pagina_a:/intervallo_pagine:e21395/volume:35
Background and AimsNon-alcoholic fatty liver disease and related hepatic syndromes affect up to one third of the adult population. The molecular mechanisms underlying NAFL etiology remain elusive. Nuclear Protein 1 (NUPR1) expression increases upon c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd733e9719455f742cc0ef85de4759e
https://ir.lib.uwo.ca/paedpub/570
https://ir.lib.uwo.ca/paedpub/570