Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marion Rohmer"'
Autor:
Jens Weingarten, Melanie Laßek, Benjamin F. Mueller, Marion Rohmer, Dominic Baeumlisberger, Benedikt Beckert, Jens Ade, Patricia Gogesch, Amparo Acker-Palmer, Michael Karas, Walter Volknandt
Publikováno v:
Proteomes, Vol 3, Iss 2, Pp 74-88 (2015)
Neurotransmitter release as well as structural and functional dynamics at the presynaptic active zone (PAZ) comprising synaptic vesicles attached to the presynaptic plasma membrane are mediated and controlled by its proteinaceous components. Here we
Externí odkaz:
https://doaj.org/article/b8d1293d2bdc4cdf8fbe0dc83f95f3e0
Autor:
Melanie Laßek, Jens Weingarten, Martin Wegner, Benjamin F Mueller, Marion Rohmer, Dominic Baeumlisberger, Tabiwang N Arrey, Meike Hick, Jörg Ackermann, Amparo Acker-Palmer, Ina Koch, Ulrike Müller, Michael Karas, Walter Volknandt
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004832 (2016)
The hallmarks of Alzheimer's disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of hi
Externí odkaz:
https://doaj.org/article/12eaa764d02a488986ca2d8a8ced81be
Autor:
Melanie Laßek, Jens Weingarten, Marion Rohmer, Ilaria Lunger, Simone Dudek, Walter Volknandt, Benjamin F. Mueller, Michael Karas, Patricia Gogesch, Dominic Baeumlisberger
Publikováno v:
Molecular and Cellular Neuroscience. 59:106-118
Neurotransmitter release as well as the structural and functional dynamics of the presynaptic active zone is controlled by proteinaceous components. Here we describe for the first time an experimental approach for the isolation of the presynaptic act
Publikováno v:
International Journal of Mass Spectrometry. :37-44
Although less specific proteases have been established in proteomics, resulting peptides are often disadvantaged in mass spectrometric analysis compared to tryptic peptides. This is due to the high number of theoretically possible peptides as well as
Autor:
Marion Rohmer, Wolf D. Lehmann, Dominic Baeumlisberger, Martin E. Boehm, Michael Karas, Anna Konopka
Publikováno v:
Analytical and Bioanalytical Chemistry. 404:1079-1087
Stable isotope dilution-based quantitative proteomics with intact labeled proteins as internal standards in combination with a bottom-up approach, i.e., with quantification on the peptide level, is an established method. To explore the technical prec
Publikováno v:
International Journal of Mass Spectrometry. 305:199-208
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry is a highly appreciated method in oligosaccharide analysis due to its high sensitivity and ease of use. As underivatized oligosaccharides suffer from low ionization efficien
Autor:
Jörg Ackermann, Ulrike Müller, Michael Karas, Martin Wegner, Jens Weingarten, Meike Hick, Amparo Acker-Palmer, Marion Rohmer, Dominic Baeumlisberger, Ina Koch, Walter Volknandt, Tabiwang N. Arrey, Benjamin F. Mueller, Melanie Laßek
Publikováno v:
PLoS Computational Biology
PLoS Comput Biol
PLoS Computational Biology, Vol 12, Iss 4, p e1004832 (2016)
PLoS Comput Biol
PLoS Computational Biology, Vol 12, Iss 4, p e1004832 (2016)
The hallmarks of Alzheimer’s disease (AD) are characterized by cognitive decline and behavioral changes. The most prominent brain region affected by the progression of AD is the hippocampal formation. The pathogenesis involves a successive loss of
Autor:
Marion Rohmer, Tabiwang N. Arrey, Dominic Baeumlisberger, Michael Karas, Sandra Bornemann, Jan Gorka, Dimitrios G. Papasotiriou, Ute Bahr
Publikováno v:
Analytical biochemistry. 424(2)
Detergents are frequently used for the solubilization of membrane proteins during and after purification steps. Unfortunately some of these detergents impair chromatographic separations and mass spectrometry (MS) analysis. Perfusion reversed-phase hi
Autor:
Guenes Barka, Tabiwang N. Arrey, Dominic Baeumlisberger, Marion Rohmer, Ute Bahr, Benjamin F. Mueller, Michael Karas, Tobias Beckhaus
Publikováno v:
Journal of proteome research. 10(6)
The beneficial effect of high mass accuracy in mass spectrometry is especially pronounced when using less specific enzymes as the number of theoretically possible peptides increases dramatically without any cleavage specificity defined. Together with
Autor:
Dominic Baeumlisberger, Michael Karas, Benjamin Rietschel, Dimitrios G. Papasotiriou, Marion Rohmer, Tabiwang N. Arrey, Tobias Beckhaus, Benjamin F. Mueller
Publikováno v:
Proteomics. 10(21)
The applicability of the less specific protease elastase for the identification of membrane and cytosolic proteins has already been demonstrated. MALDI as ionization technique particularly favors the detection of basic and to a lesser extent of weakl