Blocking negative effects of senescence in human skin fibroblasts with a plant extract

Autor: Ingo Lämmermann, Lucia Terlecki-Zaniewicz, Regina Weinmüllner, Markus Schosserer, Hanna Dellago, André Dargen de Matos Branco, Dominik Autheried, Benjamin Sevcnikar, Lisa Kleissl, Irina Berlin, Frédérique Morizot, Francois Lejeune, Nicola Fuzzati, Sandra Forestier, Alix Toribio, Anaïs Tromeur, Lionel Weinberg, Juan Carlos Higareda Almaraz, Marcel Scheideler, Marion Rietveld, Abdoel El Ghalbzouri, Erwin Tschachler, Florian Gruber, Johannes Grillari

Publikováno v: npj Aging and Mechanisms of Disease, Vol 4, Iss 1, Pp 1-10 (2018)

Skin aging: Plant extract blocks negative effects of senescence A plant extract from the goldenrod (Solidago virgaurea) ameliorates the negative influence of senescent cells, which accumulate in the skin with aging and create a tissue environment tha

Externí odkaz: https://doaj.org/article/1e51e56bcd8c4ecab59c13e58909e43a

Human papillary and reticular fibroblasts show distinct functions on tumor behavior in 3D-organotypic cultures mimicking melanoma and HNSCC

Autor: Shidi Wu, Marion Rietveld, Marieke Hogervorst, Frank de Gruijl, Sjoerd van der Burg, Maarten Vermeer, Remco van Doorn, Marij Welters, Abdoelwaheb El Ghalbzouri

Publikováno v: International Journal of Molecular Sciences, 23(19). MDPI
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11651

Human dermis can be morphologically divided into the upper papillary and lower reticular dermis. Previously, we demonstrated that papillary (PFs) and reticular (RFs) fibroblasts show distinct morphology and gene expression profiles. Moreover, they di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::170585e670d36372c8916559486bad09
https://hdl.handle.net/1887/3513356

The effect of TGFβRI inhibition on fibroblast heterogeneity in hypertrophic scar 2D in vitro models

Autor: Jacoba J. Out-Luiting, Rajiv S. Raktoe, Remco van Doorn, Paul P. M. van Zuijlen, Abdoelwaheb El Ghalbzouri, Marianna Kruithof-de Julio, Marion Rietveld

Publikováno v: Burns, 47(7), 1563-1575. Elsevier Limited
Raktoe, R S, Rietveld, M H, Out-Luiting, J J, Kruithof-de Julio, M, van Zuijlen, P P M, van Doorn, R & el Ghalbzouri, A 2021, ' The effect of TGFβRI inhibition on fibroblast heterogeneity in hypertrophic scar 2D in vitro models ', Burns, vol. 47, no. 7, pp. 1563-1575 . https://doi.org/10.1016/j.burns.2021.01.004
Raktoe, Rajiv S; Rietveld, Marion H; Out-Luiting, Jacoba J; Kruithof-de Julio, Marianna; van Zuijlen, Paul P M; van Doorn, Remco; El Ghalbzouri, Abdoelwaheb (2021). The effect of TGFβRI inhibition on fibroblast heterogeneity in hypertrophic scar 2D in vitro models. Burns, 47(7), pp. 1563-1575. Elsevier 10.1016/j.burns.2021.01.004

In burn patients, wound healing is often accompanied by hypertrophic scarring (HTS), resulting in both functional and aesthetic problems. HTSs are characterized by abundant presence of myofibroblasts (MFs) residing in the dermis. HTS development and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48cb5bbc394653670ef819899909a0d

Eradication of meticillin-resistant Staphylococcus aureus from human skin by the novel LL-37-derived peptide P10 in four pharmaceutical ointments

Autor: Marion Rietveld, Jan W. Drijfhout, Alwin E. Adriaans, Peter H. Nibbering, Kirsten J. M. Schimmel, Robert A. Cordfunke, Suzan Commandeur, Sarah Zwart, Abdoelwaheb El Ghalbzouri, Elisabeth M. Haisma, Anikó Göblyös, Bep Ravensbergen, Jan den Hartigh, Remko van Leeuwen

Publikováno v: International Journal of Antimicrobial Agents, 54(5), 610-618. ELSEVIER

Skin bacterial colonization/infection is a frequent cause of morbidity in patients with chronic wounds and allergic/inflammatory skin diseases. This study aimed to develop a novel approach to eradicate meticillin-resistant Staphylococcus aureus (MRSA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1d989a7219782a5a850e344b063d61
http://hdl.handle.net/1887/122411

Differential effect of extracellular matrix derived from papillary and reticular fibroblasts on epidermal development in vitro

Autor: Gaelle Saintigny, David Janson, Christian Mahé, Abdoelwaheb El Ghalbzouri, Marion Rietveld

Publikováno v: European Journal of Dermatology, 27(3), 237-246

Papillary and reticular fibroblasts have different effects on keratinocyte proliferation and differentiation. The aim of this study was to investigate whether these effects are caused by differential secretion of soluble factors or by differential ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711051fb6403fefe6a095dfccb801900
https://hdl.handle.net/1887/115804