Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Marion Rensinghoff"'
Autor:
Srinivasa Rao, Bandi, Christian, Brandts, Marion, Rensinghoff, Rebekka, Grundler, Lara, Tickenbrock, Gabriele, Köhler, Justus, Duyster, Wolfgang E, Berdel, Carsten, Müller-Tidow, Hubert, Serve, Bülent, Sargin, Martin, Wolf
Publikováno v:
Blood. 114(19)
Somatic mutations of Kit have been found in leukemias and gastrointestinal stromal tumors. The proto-oncogene c-Cbl negatively regulates Kit and Flt3 by its E3 ligase activity and acts as a scaffold. We recently identified the first c-Cbl mutation in
Autor:
Carsten Müller-Tidow, Chunaram Choudhary, Ivan Dikic, Bülent Sargin, Benjamin August, Mirko H. H. Schmidt, Hubert Serve, Lara Tickenbrock, Joachim Schwäble, Rebekka Grundler, Marion Rensinghoff, Wolfgang E. Berdel, Srinivasa Rao Bandi, Christine Thiessen, Christian Brandts, Justus Duyster, Steffen Koschmieder, Nicola Crosetto
Publikováno v:
Blood. 110(3)
In acute myeloid leukemia (AML), mutational activation of the receptor tyrosine kinase (RTK) Flt3 is frequently involved in leukemic transformation. However, little is known about a possible role of highly expressed wild-type Flt3 in AML. The proto-o
Autor:
Lara Tickenbrock, Marion Rensinghoff, Carsten Müller-Tidow, Rebekka Grundler, Wolfgang E. Berdel, Justus Duyster, Srinivasa Rao Bandi, Hubert Serve, Christian Brandts
Publikováno v:
Blood. 114:3970-3970
Abstract 3970 Poster Board III-906 Purpose The Cbl proto-oncogene products have emerged as important components of the signal transduction cascades downstream of both non-receptor and receptor tyrosine kinases (RTKs). By regulation of receptor traffi
Autor:
Rebekka Grundler, Carsten Müller-Tidow, Marion Rensinghoff, Christian Brandts, Hubert Serve, Justus Duyster, Lara Tickenbrock, Srinivasa Rao Bandi, Wolfgang E. Berdel, Gabriele Köhler
Publikováno v:
Blood. 114:3973-3973
Abstract 3973 Poster Board III-909 Purpose Somatic mutations of Kit have been found in leukemias and gastrointestinal stromal tumors. The proto-oncogene c-Cbl negatively regulates Kit and Flt3 by its E3 ligase activity and acts as a scaffold for seve
Autor:
Wolfgang E. Berdel, Srinivasa Rao Bandi, Pavan Nagaruri Gonchi, Benjamin August, Bülent Sargin, Chunaram Choudhary, Carsten Müller-Tidow, Hubert Serve, Marion Rensinghoff
Publikováno v:
Blood. 110:2198-2198
The Cbl proto-oncogene products have emerged as important components of the signal transduction cascades downstream of both non-receptor and receptor tyrosine kinases (RTKs). By regulation of receptor trafficking and degradation, they have been shown