Výsledky vyhledávání - "Marion Piquemal"

Correlations Between Mutant Huntingtin Aggregates and Behavioral Changes in R6/1 Mice

Autor: Syndelle Arnaud, Marion Piquemal, Maurice Garret, Yoon H. Cho, Cristiana Pistono, Divyangana Rakesh, Elodie Poinama, Magali Cabanas, Jean-Louis Guillou

Publikováno v: Journal of Huntington's Disease. 9:33-45

BACKGROUND Huntington's disease (HD) is a neurodegenerative disorder caused by the expansion of the trinucleotide CAG in the HD gene. While the presence of nuclear aggregates of mutant huntingtin (mHtt) in neurons is a hallmark of HD, the reason behi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee88fa645e5b7ed65c13a4ef7b8c017f
https://doi.org/10.3233/jhd-190352

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Chlorzoxazone, A BKCa Channel Agonist, Rescues The Pathological Phenotypes Of Williams-Beuren Syndrome In A Preclinical Model

Autor: Marion Piquemal, Noura Abdulkarim-Abdalla, Paula Ortiz-Romero, Valerie Lemaire-Mayo, Wim E. Crusio, Eric Louette, Victoria Campuzano, Susanna Pietropaolo

Williams-Beuren syndrome (WBS) is a rare developmental disorder caused by the deletion of a 1.5 Mb region in chromosome 7 (7q11.23). WBS has been recently modelled by a mutant mouse line having a complete deletion (CD) of the equivalent locus on mous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546e0182c8beb66c26b0723e856076bd
https://hal.archives-ouvertes.fr/hal-03393773/document

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Autophagy is used as a survival program in unfertilized sea urchin eggs that are destined to die by apoptosis after inactivation of MAPK1/3 (ERK2/1)

Autor: Ludivine Houel-Renault, Marion Piquemal, Laetitia Philippe, Brigitte Ciapa

Publikováno v: Autophagy. 9:1527-1539

A high MAPK1/3 (also known as ERK2/1, respectively) activity, preventing spontaneous activation, is essential to maintain cell cycle arrest of mature oocytes of mammals, frogs or invertebrates such as starfish. Mature oocytes would undergo a "suicide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c4f65d9fa7ed20587bf98088684b98
https://doi.org/10.4161/auto.25712

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Different routes lead to apoptosis in unfertilized sea urchin eggs

Autor: Lucie Tosca, Marion Piquemal, Laetitia Philippe, Wen Ling Zhang, Brigitte Ciapa

Publikováno v: Apoptosis
Apoptosis, Springer Verlag, 2014, 19 (3), pp.436-50. ⟨10.1007/s10495-013-0950-3⟩

Results obtained in various species, from mammals to invertebrates, show that arrest in the cell cycle of mature oocytes is due to a high ERK activity. Apoptosis is stimulated in these oocytes if fertilization does not occur. Our previous data sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c9be664f85373525c6eaaeedf2597a
https://hal.archives-ouvertes.fr/hal-01101287

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