Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Marion Muhly Reinholz"'
Autor:
Mariana Shumliakivska, Guillermo Luxán, Inga Hemmerling, Marina Scheller, Xue Li, Carsten Müller-Tidow, Bianca Schuhmacher, Zhengwu Sun, Andreas Dendorfer, Alisa Debes, Simone-Franziska Glaser, Marion Muhly-Reinholz, Klara Kirschbaum, Jedrzej Hoffmann, Eike Nagel, Valentina O. Puntmann, Sebastian Cremer, Florian Leuschner, Wesley Tyler Abplanalp, David John, Andreas M. Zeiher, Stefanie Dimmeler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Hematopoietic mutations in epigenetic regulators like DNA methyltransferase 3 alpha (DNMT3A), play a pivotal role in driving clonal hematopoiesis of indeterminate potential (CHIP), and are associated with unfavorable outcomes in patients suf
Externí odkaz:
https://doaj.org/article/20a09696ec974f6db501fff88d7fff78
Autor:
Jedrzej Hoffmann, Guillermo Luxán, Wesley Tyler Abplanalp, Simone-Franziska Glaser, Tina Rasper, Ariane Fischer, Marion Muhly-Reinholz, Michael Potente, Birgit Assmus, David John, Andreas Michael Zeiher, Stefanie Dimmeler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Hematopoiesis influences the progression of cardiovascular disease, yet the influence of cardiovascular disease on the bone vasculature is unknown. Hoffmann, Luxán, Abplanalp et al. describe the response of the bone cell composition to myocardial in
Externí odkaz:
https://doaj.org/article/398da0beec4046aba06db75788ef5a98
Autor:
Lukas S. Tombor, David John, Simone F. Glaser, Guillermo Luxán, Elvira Forte, Milena Furtado, Nadia Rosenthal, Nina Baumgarten, Marcel H. Schulz, Janina Wittig, Eva-Maria Rogg, Yosif Manavski, Ariane Fischer, Marion Muhly-Reinholz, Kathrin Klee, Mario Looso, Carmen Selignow, Till Acker, Sofia-Iris Bibli, Ingrid Fleming, Ralph Patrick, Richard P. Harvey, Wesley T. Abplanalp, Stefanie Dimmeler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Endothelial cells play a critical role in the adaptation of tissues to injury and show a remarkable plasticity. Here the authors show, using single cell sequencing, that endothelial cells acquire a transient mesenchymal state associated with metaboli
Externí odkaz:
https://doaj.org/article/1006b6d795e44cc8b2756328c762cb7b
Autor:
Mariana Shumliakivska, Guillermo Luxán, Inga Hemmerling, Wesley Tyler Abplanalp, Xue Li, Marina Scheller, Carsten Müller-Tidow, Florian Leuschner, Bianca Schuhmacher, Alisa Debes, Simone-Franziska Glaser, Marion Muhly Reinholz, Klara Kirschbaum, Jedrzej Hoffmann, Eike Nagel, Valentina O. Puntmann, David John, Sebastian Cremer, Andreas M. Zeiher, Stefanie Dimmeler
Hematopoietic mutations in epigenetic regulators like DNA methyltransferase 3 alpha (DNMT3A) drive clonal hematopoiesis of indeterminate potential (CHIP) and are associated with adverse prognosis in patients with heart failure (HF). The interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8310eae50b004417fcee625b308391df
https://doi.org/10.1101/2023.01.07.521766
https://doi.org/10.1101/2023.01.07.521766
Autor:
Guillermo Luxán, Marion Muhly-Reinholz, Simone F. Glaser, Johannes Trebing, Christoph Reich, Jan Haas, Farbod Sedaghat-Hamedani, Benjamin Meder, Stefanie Dimmeler
Cardiac homeostasis relies on the appropriate provision of nutrients and functional specialization of local endothelial cells. Previously we reported in this journal that the endothelial Eph-ephrin signalling, in particular the ligand EphB4, is requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0afe2c8d0dd2c31cac5337ddf23f5a71
https://doi.org/10.1101/2022.12.16.22283442
https://doi.org/10.1101/2022.12.16.22283442
Autor:
Julian U. G. Wagner, Lukas Tombor, Pedro Felipe Malacarne, Lisa-Maria Kettenhausen, Josefine Panthel, Maria Cipca, Kathrin A. Stilz, Ariane Fischer, Marion Muhly-Reinholz, Wesley T. Abplanalp, David John, Giulia K. Buchmann, Stephan Angendohr, Ehsan Amin, Katharina Scherschel, Nikolaj Klöcker, Malte Kelm, Dominik Schüttler, Sebastian Clauss, Stefan Guenther, Thomas Boettger, Thomas Braun, Christian Bär, Eleonora Nardini, Selma Osmanagic-Myers, Christian Meyer, Andreas M. Zeiher, Ralf P. Brandes, Guillermo Luxán, Stefanie Dimmeler
Aging is a major risk factor for impaired cardiovascular health. The aging myocardium is characterized by electrophysiological dysfunctions such as a reduced heart rate variability. These alterations can be intrinsic within cardiomyocytes, but might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37a05188cdbda288f09c07dba5011bf
https://doi.org/10.1101/2022.07.29.501999
https://doi.org/10.1101/2022.07.29.501999
Autor:
Konstantin Mayer, Reinhold Schmidt, Marion Muhly-Reinholz, Tina Bögeholz, Stephanie Gokorsch, Friedrich Grimminger, Werner Seeger
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 6, Pp 944-951 (2002)
Severe endothelial abnormalities are a prominent feature in sepsis with cytokines such as tumor necrosis factor (TNF)α being implicated in the pathogenesis. As mimic to inflammation, human umbilical vascular endothelial cells (HUVEC) were incubated
Externí odkaz:
https://doaj.org/article/07b15dd62ef248458da6c880195fe711
Autor:
Simone-Franziska Glaser, Till Acker, Milena B. Furtado, Elvira Forte, Nadia A. Rosenthal, Yosif Manavski, Marion Muhly-Reinholz, Lukas Tombor, Ariane Fischer, David John, Richard P. Harvey, A Abplanalp, Guillermo Luxán, Mario Looso, S Dimmeler
Publikováno v:
European Heart Journal. 41
After myocardial infarct (MI), followed by ischemia and scar formation, interstitial cells play key roles in the adaptation to injury. Endothelial cells (ECs), for instance, can clonally expand, migrate into the infarct area and facilitate crucial fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0490eafed602c099575a1a4675cf0c83
https://doi.org/10.1093/ehjci/ehaa946.3736
https://doi.org/10.1093/ehjci/ehaa946.3736
Autor:
Birgit Assmus, Ariane Fischer, S Dimmeler, Jörg Hoffmann, Andreas M. Zeiher, Marion Muhly-Reinholz, Guillermo Luxán, Tina Rasper, Wesley Abplanalp
Publikováno v:
European Heart Journal. 41
Introduction The interface between heart and bone emerges as a key trigger of post-infarction inflammation and progression of chronic heart failure (CHF). However, our knowledge on the underlying mechanisms of this interaction is incomplete. Bone vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96403a313f881f92172e64de82050939
https://doi.org/10.1093/ehjci/ehaa946.0874
https://doi.org/10.1093/ehjci/ehaa946.0874
Autor:
David John, Marion Muhly-Reinholz, Simone-Franziska Glaser, Andreas M. Zeiher, Stefanie Dimmeler, Jedrzej Hoffmann, Wesley Abplanalp, Birgit Assmus, Ariane Fischer, Guillermo Luxán, Tina Rasper
SummaryBone vasculature provides protection and signals necessary to control stem cell quiescence and renewal1. Specifically, type H capillaries, which highly express Endomucin, constitute the endothelial niche supporting a microenvironment of osteop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8b938625c647eaaa676b7cb446bab1
https://doi.org/10.1101/2020.05.29.123711
https://doi.org/10.1101/2020.05.29.123711