Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Marion Laudette"'
Autor:
Mathieu Cinato, Linda Andersson, Azra Miljanovic, Marion Laudette, Oksana Kunduzova, Jan Borén, Malin C. Levin
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 209 (2024)
Oxidative stress is the imbalance between the production of reactive oxygen species (ROS) and antioxidants in a cell. In the heart, oxidative stress may deteriorate calcium handling, cause arrhythmia, and enhance maladaptive cardiac remodeling by the
Externí odkaz:
https://doaj.org/article/14b1bc5a21f348e8a4c9441215a3f3cd
Autor:
Marianne Mazevet, Anissa Belhadef, Maxance Ribeiro, Delphine Dayde, Anna Llach, Marion Laudette, Tiphaine Belleville, Philippe Mateo, Mélanie Gressette, Florence Lefebvre, Ju Chen, Christilla Bachelot-Loza, Catherine Rucker-Martin, Frank Lezoualch, Bertrand Crozatier, Jean-Pierre Benitah, Marie-Catherine Vozenin, Rodolphe Fischmeister, Ana-Maria Gomez, Christophe Lemaire, Eric Morel
Publikováno v:
eLife, Vol 12 (2023)
Anthracyclines, such as doxorubicin (Dox), are widely used chemotherapeutic agents for the treatment of solid tumors and hematologic malignancies. However, they frequently induce cardiotoxicity leading to dilated cardiomyopathy and heart failure. Thi
Externí odkaz:
https://doaj.org/article/cdffeb33bb6c47cd87e41bc7a93230d4
Autor:
Marion Laudette, Yannis Sainte-Marie, Grégoire Cousin, Dorian Bergonnier, Ismahane Belhabib, Stéphanie Brun, Karina Formoso, Loubna Laib, Florence Tortosa, Camille Bergoglio, Bertrand Marcheix, Jan Borén, Olivier Lairez, Jérémy Fauconnier, Alexandre Lucas, Jeanne Mialet-Perez, Cédric Moro, Frank Lezoualc’h
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-14 (2021)
Abstract Cyclic adenosine monophosphate (cAMP) is a master regulator of mitochondrial metabolism but its precise mechanism of action yet remains unclear. Here, we found that a dietary saturated fatty acid (FA), palmitate increased intracellular cAMP
Externí odkaz:
https://doaj.org/article/097d49210f5941459368a2114f15c98f
Publikováno v:
Cells, Vol 10, Iss 1, p 154 (2021)
β-adrenergic receptors (β-ARs) play a major role in the physiological regulation of cardiac function through signaling routes tightly controlled by G protein-coupled receptor kinases (GRKs). Although the acute stimulation of β-ARs and the subseque
Externí odkaz:
https://doaj.org/article/80e03ad485b2417da5cde443c791e518
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 9 (2018)
Evidence collected over the last ten years indicates that Epac and cAMP scaffold proteins play a critical role in integrating and transducing multiple signaling pathways at the basis of cardiac and lung physiopathology. Some of the deleterious effect
Externí odkaz:
https://doaj.org/article/dc5480c1f7be4844a702105fd2337706
Autor:
Marion Laudette, Malin Lindbom, Muhammad Arif, Mathieu Cinato, Mario Ruiz, Stephen Doran, Azra Miljanovic, Mikael Rutberg, Linda Andersson, Martina Klevstig, Marcus Henricsson, Per-Olof Bergh, Entela Bollano, Nay Aung, J Gustav Smith, Marc Pilon, Tuulia Hyötyläinen, Matej Orešič, Rosie Perkins, Adil Mardinoglu, Malin C Levin, Jan Borén
Publikováno v:
Cardiovascular Research.
Aims Pro-protein convertase subtilisin-kexin type 9 (PCSK9), which is expressed mainly in the liver and at low levels in the heart, regulates cholesterol levels by directing low-density lipoprotein receptors to degradation. Studies to determine the r
Autor:
Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Christina Drevinge, Marion Laudette, Entela Bollano, Marcus Henricsson, Johan Tolö, Marcos Bauza Thorbrügge, Max Levin, Malin Lindbom, Martina Klevstig, Per Fogelstrand, Linda Andersson, Charlotta Olofsson, Jan Borén, Malin Levin
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:143-144
Autor:
Stephen Doran, Per Fogelstrand, Martina Klevstig, Matias Ekstrand, Muhammad Arif, Martin Adiels, Adil Mardinoglu, Elmir Omerovic, Linda Andersson, Marion Laudette, Ismena Mardani, Malin Lindbom, Lisanna Sinisalu, Mathieu Cinato, Matej Orešič, Ara Koh, Malin Levin, Jan Borén, Åsa Tivesten, Anders Jeppsson, Richard L. Proia, Tuulia Hyötyläinen, Azra Miljanovic, Johannes Wikström, Entela Bollano, Max Levin, Marcus Henricsson, Martin O. Bergo, Karl Swärd
Publikováno v:
European Heart Journal
Aims Cardiac injury and remodelling are associated with the rearrangement of cardiac lipids. Glycosphingolipids are membrane lipids that are important for cellular structure and function, and cardiac dysfunction is a characteristic of rare monogenic
Autor:
Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Christina Drevinge, Marion Laudette, Entela Bollano, Marcus Henricsson, Johan Tolö, Marcos Bauza Thorbrügge, Max Levin, Malin Lindbom, Muhammad Arif, Pal Pacher, Linda Andersson, Charlotta S Olofsson, Jan Borén, Malin C Levin
Publikováno v:
Life Science Alliance. 6:e202201690
The adult heart develops hypertrophy to reduce ventricular wall stress and maintain cardiac function in response to an increased workload. Although pathological hypertrophy generally progresses to heart failure, physiological hypertrophy may be cardi
Autor:
Mélanie Gressette, Christophe Lemaire, Florence Lefebvre, A.M. Gomez, Mazevet M, B Crozatier, Philippe Mateo, Belleville T, D. Dayde, Marie-Catherine Vozenin, Eric Morel, Marion Laudette, Bachelot-Loza C, Llach A, Jingyao Chen, Catherine Rucker-Martin, Rodolphe Fischmeister, Maxance Ribeiro, A. Belhadef, Jean-Pierre Benitah, Frank Lezoualc'h
Rationale: The widely used chemotherapeutic agent Doxorubicin (Dox) induces cardiotoxicity leading to dilated cardiomyopathy and heart failure. This cardiotoxicity has been related to ROS generation, DNA intercalation, bioenergetic distress and cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971109331ada3c8e635c88b648b1417a
https://doi.org/10.1101/2021.06.16.448655
https://doi.org/10.1101/2021.06.16.448655