Role of mucosal-associated invariant T cells dynamics in pathogenesis of Sjögren syndrome

Autor: Jeanne Chauffier, Henri Berger de Gallardo, Mathieu F. Chevalier, Aïcha Kante, Marion Lambert, Xavier Cabrol, Elisa Aldersons, Stéphane Mouly, Karine Champion, Blanca Amador-Borrero, Ruxandra Burlacu, William Bigot, Homa Adle-Biassete, Rachid Kaci, Aurélie Selvanadin, Martine Cohen-Solal, Amélie Coudert, Sophie Caillat-Zucman, Damien Sène, Cloé Comarmond

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract Sjögren syndrome (SS) is an autoimmune disease characterized by chronic inflammatory infiltrates in the salivary and lacrimal glands. Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T-cells, predominantly found in mu

Externí odkaz: https://doaj.org/article/d0613dd8a50d409b92e34d52f65555fc

Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.

Autor: Stéphanie Dupuy, Marion Lambert, David Zucman, Siméon-Pierre Choukem, Sara Tognarelli, Cécile Pages, Céleste Lebbé, Sophie Caillat-Zucman

Publikováno v: PLoS Pathogens, Vol 8, Iss 1, p e1002486 (2012)

The contribution of innate immunity to immunosurveillance of the oncogenic Human Herpes Virus 8 (HHV8) has not been studied in depth. We investigated NK cell phenotype and function in 70 HHV8-infected subjects, either asymptomatic carriers or having

Externí odkaz: https://doaj.org/article/2850ba062cde4bb2920887b55ac8a325

Immune landscape after allo-HSCT: TIGIT- and CD161-expressing CD4 T cells are associated with subsequent leukemia relapse

Autor: Viviane Gournay, Nicolas Vallet, Vivien Peux, Kristi Vera, Jennifer Bordenave, Marion Lambert, Aurélien Corneau, David Michonneau, Régis Peffault de Latour, Sophie Caillat-Zucman, Gérard Socié, Mathieu F. Chevalier

Publikováno v: Blood
Blood, American Society of Hematology, In press, ⟨10.1182/blood.2022015522⟩

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the most effective treatment for selected patients with acute myeloid leukemia (AML) and relies on a “graft-versus-leukemia” effect (GVL) where donor T lymphocytes mediate control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf71c0df8cc0a276d3757aed4c6af6b7
https://doi.org/10.1182/blood.2022015522

Modeling of cold mix asphalt evolutive behaviour based on nonlinear viscoelastic spectral decomposition

Autor: Frédéric Dubois, Vincent Gaudefroy, Francois Chaignon, Marion Lambert, Anne Millien, Jean-Michel Piau, Christophe Petit

Publikováno v: Construction and Building Materials. 173:403-410

Given a political context in which energy and environmental stakes have become increasingly dominant, road engineering practices have favoured saving energy and protecting the environment. Among these practices, the use of cold mixes treated with bit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbbdb314f2d2aa7b1e4fb5c5c5c535e8
https://doi.org/10.1016/j.conbuildmat.2018.03.207

Ontogeny of human mucosal-associated invariant T cells and related T cell subsets

Autor: Jean-Sébastien Diana, Michel Peuchmaur, Jean-Hugues Dalle, Valérie Biran, Saba Azarnoush, Marie Tourret, Véronique Houdouin, Liana Ghazarian, Thomas Schmitz, Ghada Ben Youssef, Yvonne K. Mburu, Marion Lambert, Olivier Lantz, Sophie Caillat-Zucman, Marion Salou, Anne-Laure Virlouvet, Stanislas Mondot

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine 2 (215), 459-479. (2018)
Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2018, 215 (2), pp.459-479. ⟨10.1084/jem.20171739⟩

There are very few human MAIT cells in cord blood. Ben Youssef et al. show that they slowly expand during childhood and point to a critical role of the TCRαβ repertoire in determining their unique ability to recognize MR1-restricted microbial antig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f2ce3f1a156e3153d6e09335cf9e97
https://pubmed.ncbi.nlm.nih.gov/29339446